Results 71 to 80 of about 150,922 (283)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A link between the maximum entropy approach and the variational entropy form
, 2010 The maximum entropy approach operating with quite general entropy measure and constraint is considered. It is demonstrated that for a conditional or parametrized probability distribution $f(x|\mu)$ there is a "universal" relation among the entropy rate ...
E. V. VAKARIN +2 more
core +1 more source
A generalized variational formulation
Journal of Mathematical Analysis and Applications, 1974 In 1971, B. Vujanovic [I] gave a variational formulation for a broad class of parabolic partial differential equations. Although the formulation was quite unconventional, he and his co-workers [2, 31 have shown that there are numerous applications to be made with excellent results.
Atanackovic, T.M., Jones, S.E.
openaire +2 more sources
Aspects of the Schwinger multichannel variational formulation [PDF]
Physical Review A, 1988 We present a discussion which should be helpful in clarifying some key steps in the formulation of a multichannel extension of Schwinger’s variational principle for electron-molecule collisions [K. Takatsuka and V. McKoy, Phys. Rev. A 30, 1734 (1984)].
Lima, M. A. P., McKoy, V.
openaire +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
IEEE AccessUse of magnetic scalar potential instead of magnetic vector potential can dramatically reduce the computational cost for 3D magnetic field analysis, but for most methods, the use of scalar potential was limited to current-free conditions.
Jong Oh Park, Jun Seong Lee, Il Han Park
doaj +1 more source
Standard finite elements for the numerical resolution of the elliptic Monge-Ampere equation: classical solutions [PDF]
, 2015 We propose a new variational formulation of the elliptic Monge-Ampere equation and show how classical Lagrange elements can be used for the numerical resolution of classical solutions of the equation.
Awanou, Gerard
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Abstract and Applied Analysis, 2012 The paper is concerned with the variational formulation of the oligopolistic market equilibrium problem in presence of both production and demand excesses.
Annamaria Barbagallo, Paolo Mauro
doaj +1 more source