Results 131 to 140 of about 108,481 (312)

Challenges in Genomic Variant Interpretation Within Pakistani Populations due to Genomic Healthcare Inequalities

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Accurate classification of genomic variants is crucial to ensure correct diagnosis, genetic counseling, and clinical management of monogenic inherited disorders. Variant interpretation can be hindered in populations that are significantly underrepresented in large reference genomic databases, leading to genomic healthcare inequalities. Despite
Zantasha Khalid   +16 more
wiley   +1 more source

A Systematic Review of Adverse Childhood Experiences and Epigenetic Age Acceleration in Later Adult Life Measured With Second and Third‐Generation Epigenetic Clocks

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT We examined the relationship between adverse childhood experiences (ACEs) and epigenetic age acceleration (EAA) in adulthood as measured by second and third generation epigenetic clocks by performing a systematic review of the literature. The electronic databases MEDLINE and EMBASE were searched on 17 July 2023.
Matthew Green   +2 more
wiley   +1 more source

Molecular Profiling of Genes Associated With Methylphenidate Pathway Therapy and Discovery of New Variants in Amazonian Amerindian Populations

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In Attention Deficit Hyperactivity Disorder (ADHD), methylphenidate is one of the most widely used drugs, in which patient response significantly impacts prognosis. This study aimed to characterize the molecular profile of 10 genes associated with methylphenidate therapy.
Aline Pasquini Santos   +14 more
wiley   +1 more source

Community music, identity and belonging among Dutchies in Australia: Comparing assimilation to multiculturalism

open access: yesAustralian Journal of Social Issues, EarlyView.
Abstract This article discusses variations in the experiences of Dutch identity and belonging to a music‐making group in the Dutch migrant community in Melbourne, Australia. It answers the research question “Which variations of ‘Dutch identity’ are there for the participants and how does music‐making relate to this?”. Feelings of identity and belonging
Karien Dekker   +2 more
wiley   +1 more source

Caring Futures: Australian Attitudes About the Desirability of Care Work

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Amid increasing public and policy attention on the care and support sector, which millions of Australians rely upon for essential services, care workers continue to advocate for better pay and fairer conditions. This article draws on the concepts of recognition, value and social distribution from feminist ethics of care scholarship to explore ...
Laura Davy   +3 more
wiley   +1 more source

Approximation of an Inertial Iteration Method for a Set-Valued Quasi Variational Inequality

open access: yesIraqi Journal for Computer Science and Mathematics
In this article, a projection type two step inertial iterative scheme for investigating set-valued quasi variational inequality in real Banach spaces is designed. We manifest the existence result and verified by an illustrative example.
Mohammad Akram
doaj   +1 more source

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