Results 51 to 60 of about 6,816 (262)

Local Fractional Laplace Variational Iteration Method for Fractal Vehicular Traffic Flow

open access: yesAdvances in Mathematical Physics, 2014
We discuss the line partial differential equations arising in fractal vehicular traffic flow. The nondifferentiable approximate solutions are obtained by using the local fractional Laplace variational iteration method, which is the coupling method of ...
Yang Li   +3 more
doaj   +1 more source

Optimal control based on the variational iteration method

open access: yesComputers & Mathematics with Applications, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Samira Berkani   +2 more
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

On the Semi-analytical and Hybrid Methods for the Drinfeld-Sokolov-Wilson System Modelling Dispersive Water Waves

open access: yesCumhuriyet Science Journal
In this study, modified variational iteration method (MVIM), modified variational iteration Laplace transform method (MVILTM) and modified variational iteration Sumudu transform method (MVISTM) are used to examine the Drinfeld-Sokolov-Wilson (DSW) system.
Emre Aydın, İnci Çilingir Süngü
doaj   +1 more source

A variational iteration method for solving Troesch’s problem

open access: yesJournal of Computational and Applied Mathematics, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Modified variational iteration method for analytical solutions of nonlinear oscillators

open access: yesJournal of Low Frequency Noise, Vibration and Active Control, 2019
The second-order nonlinear oscillators have rich dynamics. We proposed a novel analytical method based on both variational iteration method and Adomian method. The variational iteration method is used to establish an equivalent integral system.
Wei He, Hua Kong, Yan-Mei Qin
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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