Results 61 to 70 of about 87,409 (279)

Bir Boyutlu Doğrusal Olmayan Bir Isı İletimi Probleminin Varyasyonel İterasyon Yönetimi İle Analizi [PDF]

, 2008
Konferans Bildirisi -- Teorik ve Uygulamalı Mekanik Türk Milli Komitesi, 2008Conference Paper -- Theoretical and Applied Mechanical Turkish National Committee, 2008Bu çalışmada durgun halde, doğrusal olmayan, bir boyutlu bir ısı iletimi problemi ...
Atay, Mehmet Tarık, Coşkun, Safa Bozkurt   +1 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Modified variational iteration method for analytical solutions of nonlinear oscillators

Journal of Low Frequency Noise, Vibration and Active Control, 2019
The second-order nonlinear oscillators have rich dynamics. We proposed a novel analytical method based on both variational iteration method and Adomian method. The variational iteration method is used to establish an equivalent integral system.
Wei He, Hua Kong, Yan-Mei Qin
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A New Efficient Method for solving Helmholtz and Coupled Helmholtz Equations Involving Local Fractional Operators

مجلة علوم ذي قار, 2019
In this manuscript, we apply a new technique, namely local fractional Laplace variational iteration method (LFVITM) on Helmholtz and coupled Helmholtz equations to obtain the analytical approximate solutions.
Hassan Kamil Jassim, Hasan Ali Naser, Alaa Kleef Jiheel   +2 more
doaj   +4 more sources

Solving Variational Inequalities with Monotone Operators on Domains Given by Linear Minimization Oracles [PDF]

, 2014
The standard algorithms for solving large-scale convex-concave saddle point problems, or, more generally, variational inequalities with monotone operators, are proximal type algorithms which at every iteration need to compute a prox-mapping, that is, to ...
Juditsky, Anatoli, Nemirovski, Arkadi
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

A view of Estimation of Distribution Algorithms through the lens of Expectation-Maximization

, 2020
We show that a large class of Estimation of Distribution Algorithms, including, but not limited to, Covariance Matrix Adaption, can be written as a Monte Carlo Expectation-Maximization algorithm, and as exact EM in the limit of infinite samples.
Brookes, David H., Busia, Akosua, Fannjiang, Clara, Listgarten, Jennifer, Murphy, Kevin   +4 more
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source