Results 141 to 150 of about 30,977,271 (369)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Multiplicity of solutions for a quasilinear problem with supercritical growth

open access: yesElectronic Journal of Differential Equations, 2006
The multiplicity and concentration of positive solutions are established for the equation $$ -epsilon^{p}Delta_{p}u+V(z)|u|^{p-2}u=|u|^{q-2}u +lambda|u|^{s-2}u quadhbox{in }mathbb{R}^N, $$ where ...
Giovany M. Figueiredo
doaj  

The Variational Iteration Method for Solving Asymmetric System of PDEs [PDF]

open access: yesarXiv, 2018
We propose a method to obtain iterative schemes guarantee unique solutions for systems of partial differential equations that are not symmetric with respect to the time by generalizing He variational iteration method and using Banach fixed point theorem.
arxiv  

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

Computation of dimensionless propagation parameters of LP11 mode of double clad fibers

open access: yesResults in Optics, 2023
A scalar variational approximation is proposed to calculate the propagation constant and the normalised dispersion parameter of LP11 mode of double clad fibers. Single and two parameter variational approximations have been proposed in this work.
Piusa Pratikshya Pradhan   +3 more
doaj  

GLAM: Global-Local Variation Awareness in Mamba-based World Model [PDF]

open access: yesarXiv
Mimicking the real interaction trajectory in the inference of the world model has been shown to improve the sample efficiency of model-based reinforcement learning (MBRL) algorithms. Many methods directly use known state sequences for reasoning. However, this approach fails to enhance the quality of reasoning by capturing the subtle variation between ...
arxiv  

Sensitivity Analysis of the Orthoglide, a 3-DOF Translational Parallel Kinematic Machine [PDF]

open access: yesJournal of Mechanical Design 128 (2006) 392-402, 2007
This paper presents a sensitivity analysis of the Orthoglide, a 3-DOF translational Parallel Kinematic Machine. Two complementary methods are developed to analyze its sensitivity to its dimensional and angular variations. First, a linkage kinematic analysis method is used to have a rough idea of the influence of the dimensional variations on the ...
arxiv  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Local Fractional Laplace Variational Iteration Method for Fractal Vehicular Traffic Flow

open access: yesAdvances in Mathematical Physics, 2014
We discuss the line partial differential equations arising in fractal vehicular traffic flow. The nondifferentiable approximate solutions are obtained by using the local fractional Laplace variational iteration method, which is the coupling method of ...
Yang Li   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy