Results 141 to 150 of about 30,977,271 (369)
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Multiplicity of solutions for a quasilinear problem with supercritical growth
The multiplicity and concentration of positive solutions are established for the equation $$ -epsilon^{p}Delta_{p}u+V(z)|u|^{p-2}u=|u|^{q-2}u +lambda|u|^{s-2}u quadhbox{in }mathbb{R}^N, $$ where ...
Giovany M. Figueiredo
doaj
The Variational Iteration Method for Solving Asymmetric System of PDEs [PDF]
We propose a method to obtain iterative schemes guarantee unique solutions for systems of partial differential equations that are not symmetric with respect to the time by generalizing He variational iteration method and using Banach fixed point theorem.
arxiv
Germline variants in CDKN2A wild‐type melanoma prone families
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen+5 more
wiley +1 more source
Computation of dimensionless propagation parameters of LP11 mode of double clad fibers
A scalar variational approximation is proposed to calculate the propagation constant and the normalised dispersion parameter of LP11 mode of double clad fibers. Single and two parameter variational approximations have been proposed in this work.
Piusa Pratikshya Pradhan+3 more
doaj
GLAM: Global-Local Variation Awareness in Mamba-based World Model [PDF]
Mimicking the real interaction trajectory in the inference of the world model has been shown to improve the sample efficiency of model-based reinforcement learning (MBRL) algorithms. Many methods directly use known state sequences for reasoning. However, this approach fails to enhance the quality of reasoning by capturing the subtle variation between ...
arxiv
Sensitivity Analysis of the Orthoglide, a 3-DOF Translational Parallel Kinematic Machine [PDF]
This paper presents a sensitivity analysis of the Orthoglide, a 3-DOF translational Parallel Kinematic Machine. Two complementary methods are developed to analyze its sensitivity to its dimensional and angular variations. First, a linkage kinematic analysis method is used to have a rough idea of the influence of the dimensional variations on the ...
arxiv
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Local Fractional Laplace Variational Iteration Method for Fractal Vehicular Traffic Flow
We discuss the line partial differential equations arising in fractal vehicular traffic flow. The nondifferentiable approximate solutions are obtained by using the local fractional Laplace variational iteration method, which is the coupling method of ...
Yang Li+3 more
doaj +1 more source