Results 51 to 60 of about 768,167 (340)

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

The variational Adomian decomposition method for solving nonlinear two- dimensional Volterra-Fredholm integro-differential equation

open access: yesJournal of King Saud University: Science, 2019
This paper outlines the coupling of variational iteration method (VIM) with Adomian decomposition method (ADM) for solving nonlinear mixed Volterra-Fredholm integro-diffierential equation (V-FIDE), this method is called variational Adomian decomposition ...
F.A. Hendi, M.M. Al-Qarni
doaj  

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Seismic tomography using variational inference methods [PDF]

open access: yes, 2019
Seismic tomography is a methodology to image the interior of solid or fluid media, and is often used to map properties in the subsurface of the Earth. In order to better interpret the resulting images it is important to assess imaging uncertainties.
arxiv   +1 more source

On the Variational Problems without Having Desired Variational Symmetries

open access: yesJournal of Mathematics, 2013
We will have an attempt to present a method for constructing variational problems without having a desired one-parameter transformation group as a variational symmetry.
Mehdi Nadjafikhah   +2 more
doaj   +1 more source

Variational methods for phononic calculations [PDF]

open access: yesWave Motion, 2016
Three fundamental variational principles used for solving elastodynamic eigenvalue problems are studied within the context of elastic wave propagation in periodic composites (phononics). We study the convergence of the eigenvalue problems resulting from the displacement Rayleigh quotient, the stress Rayleigh quotient and the mixed quotient.
Yan Lu, Ankit Srivastava
openaire   +3 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Variational Bayesian Algorithms for Maneuvering Target Tracking with Nonlinear Measurements in Sensor Networks

open access: yesEntropy, 2023
The variational Bayesian method solves nonlinear estimation problems by iteratively computing the integral of the marginal density. Many researchers have demonstrated the fact its performance depends on the linear approximation in the computation of the ...
Yumei Hu   +5 more
doaj   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

A variational approach to the shock structure problem [PDF]

open access: yesTheoretical and Applied Mechanics, 2005
A variational approach to the shock structure problem is proposed. The set of governing equations, consisted of n first-order ordinary differential equations accompanied with 2n boundary conditions at ±∞, is put into variational form by means of least ...
Simić Srboljub S.
doaj   +1 more source

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