Results 61 to 70 of about 66,227 (316)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Hybrid Steepest-Descent Methods for Triple Hierarchical Variational Inequalities
Journal of Function Spaces, 2015 We introduce and analyze a relaxed iterative algorithm by combining Korpelevich’s extragradient method, hybrid steepest-descent method, and Mann’s iteration method.
L. C. Ceng +3 more
doaj +1 more source
Sensitivity analysis and parameter estimation for distributed hydrological modeling: potential of variational methods [PDF]
, 2009 Variational methods are widely used for the analysis and control of computationally intensive spatially distributed systems. In particular, the adjoint state method enables a very efficient calculation of the derivatives of an objective function ...
Dartus, Denis +8 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Relative Entropy and Variational Properties of Generalized Gibbsian Measures [PDF]
, 2004 We study the relative entropy density for generalized Gibbs measures. We first show its existence and obtain a familiar expression in terms of entropy and relative energy for a class of “almost Gibbsian measures” (almost sure continuity of conditional ...
Ny, Arnaud Le, +12 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
An Optimal Control Problem Governed by a Kirchhoff-Type Variational Inequality
Journal of Applied Mathematics, 2020 This paper is concerned with an optimal control problem governed by a Kirchhoff-type variational inequality. The existence of multiplicity solutions for the Kirchhoff-type variational inequality is established by using some nonlinear analysis techniques ...
Chengfu Wang, Pengcheng Wu, Yuying Zhou
doaj +1 more source
A variational approach to the shock structure problem [PDF]
Theoretical and Applied Mechanics, 2005 A variational approach to the shock structure problem is proposed. The set of governing equations, consisted of n first-order ordinary differential equations accompanied with 2n boundary conditions at ±∞, is put into variational form by means of least ...
Simić Srboljub S.
doaj +1 more source
Total Differential Photometric Mesh Refinement with Self-Adapted Mesh Denoising
Photonics, 2022 Variational mesh refinement is a crucial step in multiview 3D reconstruction. Existing algorithms either focus on recovering mesh details or focus on suppressing noise. Approaches with consideration of both are lacking.
Yingjie Qu +4 more
doaj +1 more source
Fractional variational problems with the Riesz-Caputo derivative
, 2012 In this paper we investigate optimality conditions for fractional variational problems, with a Lagrangian depending on the Riesz-Caputo derivative. First we prove a generalized Euler-Lagrange equation for the case when the interval of integration of the ...
Almeida, R. +2 more
core +1 more source