Results 71 to 80 of about 66,227 (316)

Reissner's Mixed Variational Theorem toward MITC finite elements for multilayered plates [PDF]

open access: yes, 2013
In this paper, we analyze a two dimensional model of multilayered plates for which the main interest is to study the mechanical and physical properties, that may change in the thickness direction.
Maria Cinefra   +15 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Numerical Solution of the Inverse Problem of Determining an Unknown Source Term in a Heat Equation

open access: yesJournal of Applied Mathematics, 2012
This paper investigates the inverse problem of determining a heat source in the parabolic heat equation using the usual conditions. Firstly, the problem is reduced to an equivalent problem which is easy to handle using variational iteration method ...
Xiuming Li, Suping Qian
doaj   +1 more source

Variational Bayesian multinomial probit regression with Gaussian process priors [PDF]

open access: yes, 2006
It is well known in the statistics literature that augmenting binary and polychotomous response models with Gaussian latent variables enables exact Bayesian analysis via Gibbs sampling from the parameter posterior.
Rogers, S., Girolami, M.
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

On the Variational Problems without Having Desired Variational Symmetries

open access: yesJournal of Mathematics, 2013
We will have an attempt to present a method for constructing variational problems without having a desired one-parameter transformation group as a variational symmetry.
Mehdi Nadjafikhah   +2 more
doaj   +1 more source

On analysis error covariances in variational data assimilation

open access: yes, 2008
The problem of variational data assimilation for a nonlinear evolution model is formulated as an optimal control problem to find the initial condition function (analysis).
Shutyaev, V.   +5 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Variational model of scoliosis [PDF]

open access: yesTheoretical and Applied Mechanics, 2018
Scoliosis, being one of the most widespread spinal diseases among children, has been studied extensively throughout the history of medicine, yet there is no clear understanding of its initiating factors and the mechanogenesis of the monomorphic three ...
Popov Igor   +4 more
doaj   +1 more source

On optimal solution error covariances in variational data assimilation problems

open access: yes, 2010
The problem of variational data assimilation for a nonlinear evolution model is formulated as an optimal control problem to find unknown parameters such as distributed model coefficients or boundary conditions. The equation for the optimal solution error
Le Dimet, F.X.   +6 more
core   +1 more source

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