Results 61 to 70 of about 328,225 (327)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Numerical Solution of the Inverse Problem of Determining an Unknown Source Term in a Heat Equation

open access: yesJournal of Applied Mathematics, 2012
This paper investigates the inverse problem of determining a heat source in the parabolic heat equation using the usual conditions. Firstly, the problem is reduced to an equivalent problem which is easy to handle using variational iteration method ...
Xiuming Li, Suping Qian
doaj   +1 more source

Total Differential Photometric Mesh Refinement with Self-Adapted Mesh Denoising

open access: yesPhotonics, 2022
Variational mesh refinement is a crucial step in multiview 3D reconstruction. Existing algorithms either focus on recovering mesh details or focus on suppressing noise. Approaches with consideration of both are lacking.
Yingjie Qu   +4 more
doaj   +1 more source

Proof of the Variational Principle for a Pair Hamiltonian Boson Model

open access: yes, 2006
We give a two parameter variational formula for the grand-canonical pressure of the Pair Boson Hamiltonian model.
Pulé, Joseph V., Zagrebnov, Valentin
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

On the Variational Problems without Having Desired Variational Symmetries

open access: yesJournal of Mathematics, 2013
We will have an attempt to present a method for constructing variational problems without having a desired one-parameter transformation group as a variational symmetry.
Mehdi Nadjafikhah   +2 more
doaj   +1 more source

A variational approach to the shock structure problem [PDF]

open access: yesTheoretical and Applied Mechanics, 2005
A variational approach to the shock structure problem is proposed. The set of governing equations, consisted of n first-order ordinary differential equations accompanied with 2n boundary conditions at ±∞, is put into variational form by means of least ...
Simić Srboljub S.
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Revised Variational Iteration Method for Solving Systems of Nonlinear Fractional-Order Differential Equations

open access: yesAbstract and Applied Analysis, 2013
A modification of the variational iteration method (VIM) for solving systems of nonlinear fractional-order differential equations is proposed. The fractional derivatives are described in the Caputo sense.
C. Ünlü, H. Jafari, D. Baleanu
doaj   +1 more source

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