Results 51 to 60 of about 50,436 (310)

Infinitely many solutions for a Hénon-type system in hyperbolic space

open access: yesAdvances in Difference Equations, 2020
This paper is devoted to studying the semilinear elliptic system of Hénon type {−ΔBNu=K(d(x))Qu(u,v),−ΔBNv=K(d(x))Qv(u,v),u,v∈Hr1(BN),N≥3, $$ \textstyle\begin{cases} -\Delta _{\mathbb{B}^{N}}u= K(d(x))Q_{u}(u,v), \\ -\Delta _{\mathbb{B}^{N}}v= K(d(x))Q_ ...
Patrícia Leal da Cunha   +1 more
doaj   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

THE METHOD OF SYSTEMATIC VARIATIONS

open access: yesSoil Science, 1963
info:eu-repo/semantics ...
openaire   +3 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Some Proximal Methods for Solving Mixed Variational Inequalities

open access: yesAbstract and Applied Analysis, 2012
It is well known that the mixed variational inequalities are equivalent to the fixed point problem. We use this alternative equivalent formulation to suggest some new proximal point methods for solving the mixed variational inequalities.
Muhammad Aslam Noor, Zhenyu Huang
doaj   +1 more source

The Variate Difference Method

open access: yesSouthern Economic Journal, 1940
Commission's seal on t.-p. ; Bibliographical foot-notes. ; Mode of access: Internet.
Edgar Z. Palmer, Gerhard Tintner
openaire   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Hybrid Steepest-Descent Methods for Triple Hierarchical Variational Inequalities

open access: yesJournal of Function Spaces, 2015
We introduce and analyze a relaxed iterative algorithm by combining Korpelevich’s extragradient method, hybrid steepest-descent method, and Mann’s iteration method.
L. C. Ceng   +3 more
doaj   +1 more source

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