Results 51 to 60 of about 52,593 (299)

Some Proximal Methods for Solving Mixed Variational Inequalities

open access: yesAbstract and Applied Analysis, 2012
It is well known that the mixed variational inequalities are equivalent to the fixed point problem. We use this alternative equivalent formulation to suggest some new proximal point methods for solving the mixed variational inequalities.
Muhammad Aslam Noor, Zhenyu Huang
doaj   +1 more source

Infinitely many solutions for a Hénon-type system in hyperbolic space

open access: yesAdvances in Difference Equations, 2020
This paper is devoted to studying the semilinear elliptic system of Hénon type {−ΔBNu=K(d(x))Qu(u,v),−ΔBNv=K(d(x))Qv(u,v),u,v∈Hr1(BN),N≥3, $$ \textstyle\begin{cases} -\Delta _{\mathbb{B}^{N}}u= K(d(x))Q_{u}(u,v), \\ -\Delta _{\mathbb{B}^{N}}v= K(d(x))Q_ ...
Patrícia Leal da Cunha   +1 more
doaj   +1 more source

The Tseng’s extragradient method for semistrictly quasimonotone variational inequalities [PDF]

open access: bronze, 2022
Habib ur Rehman   +55 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Hybrid Steepest-Descent Methods for Triple Hierarchical Variational Inequalities

open access: yesJournal of Function Spaces, 2015
We introduce and analyze a relaxed iterative algorithm by combining Korpelevich’s extragradient method, hybrid steepest-descent method, and Mann’s iteration method.
L. C. Ceng   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

On a Variational Method for Stiff Differential Equations Arising from Chemistry Kinetics

open access: yesMathematics, 2019
For the approximation of stiff systems of ODEs arising from chemistry kinetics, implicit integrators emerge as good candidates. This paper proposes a variational approach for this type of systems.
Sergio Amat   +2 more
doaj   +1 more source

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