Results 71 to 80 of about 287,859 (234)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Designing rotationally invariant neural networks from PDEs and variational methods. [PDF]

open access: yesRes Math Sci, 2022
Alt T   +4 more
europepmc   +1 more source

Numerical variational methods applied to cylinder buckling

open access: yes, 2006
We review and compare different computational variational methods applied to a system of fourth order equations that arises as a model of cylinder buckling.
Horak, Jiri   +2 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Stability of solitary waves for a three-wave interaction model

open access: yesElectronic Journal of Differential Equations, 2014
In this article we consider the normalized one-dimensional three-wave interaction model $$\displaylines{ i\frac{\partial z_1}{\partial t}=- \frac{d^2z_1}{dx^2}- z_3{\bar z}_2\cr i\frac{\partial z_2}{\partial t}=- \frac{d^2z_2}{dx^2}- z_3{\bar z}_1 ...
Orlando Lopes
doaj  

Some Implicit Methods for Solving Harmonic Variational Inequalities

open access: yesInternational Journal of Analysis and Applications, 2016
In this paper, we use the auxiliary principle technique to suggest an implicit method for solving the harmonic variational inequalities. It is shown that the convergence of the proposed method only needs pseudo monotonicity of the operator, which is a ...
Muhammad Aslam Noor, Khalida Inayat Noor
doaj   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

On Solutions of Variational Inequality Problems via Iterative Methods

open access: yesAbstract and Applied Analysis, 2014
We investigate an algorithm for a common point of fixed points of a finite family of Lipschitz pseudocontractive mappings and solutions of a finite family of γ-inverse strongly accretive mappings.
Mohammed Ali Alghamdi   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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