Results 81 to 90 of about 12,052,174 (276)
Multilevel Monte Carlo methods for ensemble variational data assimilation [PDF]
Nonlinear Processes in GeophysicsEnsemble variational data assimilation relies on ensembles of forecasts to estimate the background error covariance matrix B. The ensemble can be provided by an ensemble of data assimilations (EDA), which runs independent perturbed data assimilation and ...
M. Destouches +10 more
doaj +1 more source
Designing rotationally invariant neural networks from PDEs and variational methods. [PDF]
Res Math Sci, 2022 Alt T +4 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
On Variational Fourier Particle Methods
Journal of Scientific ComputingAbstractIn this article we describe a unifying framework for variational electromagnetic particle schemes of spectral type, and we propose a novel spectral Particle-In-Cell (PIC) scheme that preserves a discrete Hamiltonian structure. Our work is based on a new abstract variational derivation of particle schemes which builds on a de Rham complex where ...
Martin Campos Pinto +3 more
openaire +4 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Stability of solitary waves for a three-wave interaction model
Electronic Journal of Differential Equations, 2014 In this article we consider the normalized one-dimensional three-wave interaction model $$\displaylines{ i\frac{\partial z_1}{\partial t}=- \frac{d^2z_1}{dx^2}- z_3{\bar z}_2\cr i\frac{\partial z_2}{\partial t}=- \frac{d^2z_2}{dx^2}- z_3{\bar z}_1 ...
Orlando Lopes
doaj
On Solutions of Variational Inequality Problems via Iterative Methods
Abstract and Applied Analysis, 2014 We investigate an algorithm for a common point of fixed points of a finite family of Lipschitz pseudocontractive mappings and solutions of a finite family of γ-inverse strongly accretive mappings.
Mohammed Ali Alghamdi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Multigrid Methods for Total Variation
Deanonymised version of the article submitted (and later accepted) to Scale-Space and Variational Methods (SSVM) 2025.
Felipe Guerra, Tuomo Valkonen
openaire +4 more sources