Results 81 to 90 of about 52,593 (299)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Quantifying the Stability of Coupled Genetic and Epigenetic Switches With Variational Methods. [PDF]
Front Genet, 2020 Sood A, Zhang B.
europepmc +1 more source
Cluster Variation Method as a Powerful Tool for Theoretical and Computational Materials Science
, 2022 Tetsuo Mohri
openalex +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Absolute Value Variational Inequalities and Dynamical Systems
International Journal of Analysis and Applications, 2020 In this paper, we consider the absolute value variational inequalities. We propose and analyze the projected dynamical system associated with absolute value variational inequalities by using the projection method.
Safeera Batool +2 more
doaj
A Total Variation Denoising Method Based on Median Filter and Phase Consistency [PDF]
, 2020 Shuo Huang, Suiren Wan
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Variational Networks: An Optimal Control Approach to Early Stopping Variational Methods for Image Restoration. [PDF]
J Math Imaging Vis, 2020 Effland A, Kobler E, Kunisch K, Pock T.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source