Results 121 to 130 of about 6,588,469 (297)

Endodontic Treatment Of Upper First Premolar With 3 Canals- Case Report

open access: yesJournal of Rawalpindi Medical College
A comprehensive understanding of the root structure is important for the successful outcome of endodontic procedures. Lack of knowledge of the anatomic variations in root canal morphology can contribute to the failure of root canal therapy.
Dania Khan   +5 more
doaj   +1 more source

Dilemmas and controversies in the interpretation of laboratory results [PDF]

open access: yesJournal of Medical Biochemistry, 2008
Concentration of many substances in blood is a good indicator of the physiologic state of a patient. It is usual that results obtained represent the real concentration of tested substances in a patient, that is, represent his physiological state.
Popović Danica, Popović Mirko
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

CLIMATE CHARACTERISTICS ALONG THE BULGARIAN BLACK SEA COAST FROM 1970 TO 2009 [PDF]

open access: yesAerul şi Apa: Componente ale Mediului, 2013
For the regime of meteorological elements in Bulgaria influence have air masses coming from Atlantic Ocean, Mediterranean and Black Sea, and from mainland Europe.
VENETA IVANOVA TODOROVA
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Christian ethic of inclusive leadership within diastratic diversity: employing liminality as an analytical tool.

open access: yesKoers : Bulletin for Christian Scholarship, 2018
This article discerns the ingredients leadership ought to employ when it functions within the plurifactorial dimensions of the sociological, economic, political, cultural, religious and class  diversity.
Jennifer SLATER
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Generalized quasi-variational hemi-variational inequalities

open access: yesApplied Mathematics Letters, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Home - About - Disclaimer - Privacy