Results 101 to 110 of about 217,756 (210)

Long‐Term Safety and Efficacy of Obeticholic Acid in Patients With Primary Biliary Cholangitis: Final Results of the POISE Long‐Term Safety Extension

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 8, Page 1083-1096, October 2026.
In the POISE open‐label extension, patients with primary biliary cholangitis with inadequate response or intolerance to ursodeoxycholic acid received long‐term obeticholic acid (OCA) treatment. Findings demonstrated a safety profile consistent with the known characteristics of OCA, with no unexpected safety signals, while supporting sustained efficacy ...
Christopher L. Bowlus, Frederik Nevens, Kris V. Kowdley, Alan Bonder, Thomas Capozza, Jing Li, Radhika Nair, Michael Trauner, David E. Jones   +8 more
wiley   +1 more source

Noninvasive predictors of variceal bleeding after clearance of the hepatitis C virus by direct antiviral drugs

Egyptian Liver Journal
Background The introduction of direct-acting antiviral drugs (DAAs) could safely eliminate the hepatitis C virus (HCV). Steatosis and fibrosis regression after HCV treatment could occur with subsequent improvement in the portal pressure.
Sameh A. Lashen, Marwa I. Mohammed, Mariam M. Algeishy, Khaled Ali Abdel Aty, Mohammed H. Arafa, Hussein Mahmoud Saad, Walid I. Yousif   +6 more
doaj   +1 more source

Review article: Immunosuppression in Decompensated Autoimmune Hepatitis Cirrhosis ‐ To Suppress or Not to Suppress?

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 897-918, October 2026.
Individualized assessment identifies patients with decompensated autoimmune hepatitis cirrhosis who are likely to benefit from a time‐limited trial of immunosuppression versus those requiring immediate liver transplant evaluation. Early objective response monitoring (bilirubin, MELD‐Na and AST/ALT) guides continuation of immunosuppression, promotes ...
Pedro Robson Costa Passos, Valbert Oliveira Costa Filho, Guilherme Grossi Lopes Cançado   +2 more
wiley   +1 more source

Patients with conventional treatment for variceal bleeding (n = 71).

, 2015
Description of patients with variceal bleeding and conventional treatment: tabular description of patients average age, sex, prevalence of cirrhosis, etiology of cirrhosis, prevalence of previous bleeding episodes, distribution of varices, Paquet Grade ...
Thomas Seufferlein (232037), Lukas Perkhofer (758738), Martin Wagner (72668), Martin Müller (63583), Alexander Kleger (226596)   +4 more
core   +1 more source

Liver cirrhosis is associated with altered glucocorticoid metabolism related to disease severity

Journal of Internal Medicine, Volume 300, Issue 4, Page 513-527, October 2026.
Abstract Background Liver cirrhosis (LC) is frequently complicated by adrenal dysfunction; however, whether cirrhosis drives the coordinated, pathway‐specific reprogramming of cortisol metabolism remains unclear. Objectives We aimed to characterize axis‐specific alterations in cortisol metabolism in patients with LC, those with adrenal insufficiency ...
Soyeon Park, Min Jeong Park, Hye Won Yang, Jeayeon Park, Su Jong Yu, Seung Shin Park, Man‐Ho Choi, Eun Ju Cho, Jung Hee Kim   +8 more
wiley   +1 more source

Endoscopic variceal ligation vs. propranolol for prevention of first variceal bleeding: a randomized controlled trial

, 2005
Objectives Data in the literature regarding the role of endoscopic variceal ligation for the prevention of first variceal bleeding in cirrhotic patients are controversial.
Elefsiniotis, I, Goulas, S, Mavrogiannis, C, Galanis, P, Liatsos, C, Papanikolaou, IS, Psilopoulos, D, Sparos, L   +7 more
core   +1 more source

Prognostic Value of Liver Stiffness in Advanced Chronic Liver Disease After Hepatitis C Virus Eradication

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background & Aim Sustained‐virological‐response (SVR) after direct‐acting‐antiviral (DAA) therapy improves outcomes in patients with HCV‐related compensated‐advanced‐chronic‐liver‐disease (cACLD). However, it remains unclear whether absolute post‐SVR LSM or LSM reduction better predicts prognosis after SVR.
Federica Cerini, Mariagrazia Rumi, Jonas Schropp, Agostino Cosenza, Carmelo Selvaggio, Chiara Masellis, Annalisa Berzigotti   +6 more
wiley   +1 more source

Avaliação da necessidade de transfusão em pacientes submetidos à endoscopia digestiva alta por sangramento gastrointestinal superior. [PDF]

, 1994
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Braga, Márcia Regina Paim
core  

Equal efficacy of endoscopic variceal ligation and propranolol in preventing variceal bleeding in patients with noncirrhotic portal hypertension

, 2010
Background & Aims: Variceal bleeding increases morbidity and mortality among patients with noncirrhotic portal hypertension (NCPH). Blockers of β-adrenergic receptor signaling and endoscopic variceal ligation (EVL) have been used to prevent ...
Barjesh Chander Sharma, Smruti Ranjan Mishra, Sarin, Shiv Kumar, Jha, Sanjeev Kumar, Amit Agrawal, Sanjeev Kumar Jha, Gupta, Nitin, Sharma, Barjesh Chander, Shiv Kumar Sarin, Agrawal, Amit, Kumar, Ashish, Ashish Kumar, Nitin Gupta, Mishra, Smruti Ranjan   +13 more
core   +1 more source

Liver and Spleen Stiffness as Non‐Invasive Tools Assessing Liver Congestion in Patients With Budd‐Chiari Syndrome

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background and Aims Assessing liver congestion and portal hypertension (PHT) in Budd–Chiari syndrome (BCS) remains challenging. We evaluated liver and spleen stiffness measurements (LSM, SSM) obtained by transient elastography as non‐invasive tools for identifying clinically meaningful liver congestion in BCS.
Andreea Fodor, Marcos A. Thompson, Oana Nicoara‐Farcau, Ernesto Belmonte, Ángeles Garcia‐Criado, Anna Darnell, Valeria Pérez‐Campuzano, Pamela Vizcarra, Isabel Requejo, Ángeles Falga, Marina Veléz, Irene Fernandez, Adriana Sueiras, Sonia Torres, Jakub Gazda, Anna Baiges, Sarah Shalaby, Asunción Ojeda, Diego San Martin, Bogdan Procopet, Virginia Hernández‐Gea, Fanny Turon, Juan Carlos García‐Pagan   +22 more
wiley   +1 more source