Results 71 to 80 of about 217,756 (210)

Review Article: Fibrosis Reversal in Metabolic Dysfunction‐Associated Steatohepatitis—The Promise of Emerging Therapeutics

Alimentary Pharmacology &Therapeutics, EarlyView.
Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub, Tsubasa Tsutsumi, Mary E. Rinella   +2 more
wiley   +1 more source

Risk factors for Variceal Bleeding

, 1999
Variceal bleeding is the most serious complication of portal hypertension.  It is seen in 50-60% of patients with cirrhosis.  The mortality in patients wo develop gastroesophageal variceal bleeding is approximately one third.
Arnaout, Angel
core   +1 more source

National Consensus on Management of Non-Variceal Upper Gastrointestinal Tract Bleeding in Indonesia

Acta Medica Indonesiana, 2016
he Indonesian Society of Gastroenterology has compiled a national consensus guideline for the management of non-variceal upper gastrointestinal bleeding (NVUGIB).
The Indonesian Society of Gastroenterolo The Indonesian Society of Gastroenterology
doaj   +2 more sources

Transjugular intrahepatic portosystemic stent shunt placement and embolization for hemorrhage associated with rupture of anorectal varices

Journal of International Medical Research, 2018
Portal hypertension can lead to ectopic varices, which occur most frequently in the rectum. Rectal variceal bleeding in patients with portal hypertension is rare but can be life-threatening if not diagnosed and treated in a timely manner.
Xiuyan Wu, Wei Xuan, Lei Song
doaj   +1 more source

Pruritus Is Frequent and Persistent and Impacts Quality of Life Among Patients With Primary Sclerosing Cholangitis

Alimentary Pharmacology &Therapeutics, EarlyView.
Among 200 patients with primary sclerosing cholangitis, 38% reported moderate to severe pruritus in the past 6 months. During 6 months of follow up, pruritus severity fluctuated significantly. Pruritus severity was linked to worse colitis activity and lower quality of life.
Richard Dean, Maryam Yazdanfar, Joseph Zepeda, Isha J. Patel, Cynthia Levy, Craig Lammert, Raghav Bordia, Duru Cosar, Katherine Specht, Daniel Pratt, Stuart C. Gordon, Lisa Forman, Fawzy Barry, Michael Li, Usha Gungabissoon, Megan M. McLaughlin, Christopher L. Bowlus   +16 more
wiley   +1 more source

Outcomes of patients with hepatocellular carcinoma presenting with variceal bleeding

, 2004
OBJECTIVE: Variceal bleeding is an important manifestation of hepatocellular carcinoma (HCC). However, little has been documented in the literature regarding the outcomes of HCC patients presenting with variceal bleeding.
Wong, J, Lang, BH, Fan, ST, Poon, RT
core   +1 more source

Baseline and Longitudinal Liver Stiffness Measurement Predict Outcomes in Primary Biliary Cholangitis: A Multicenter Study

Hepatology Research, EarlyView.
We conducted a multicenter cohort study analyzed 454 Japanese PBC patients. Baseline LSM ≥ 8.0 kPa was independently associated with adverse outcomes. ΔLSM/year ≥ 2.1 kPa was independently associated with adverse outcomes. ABSTRACT Background & Aims Liver stiffness measurement (LSM) using vibration‐controlled transient elastography (VCTE) is a ...
Yuki Yamashita, Takefumi Kimura, Kaede Fujita, Taiki Okumura, Takanobu Iwadare, Hiroyuki Kobayashi, Shun‐ichi Wakabayashi, Tomoo Yamazaki, Satoru Joshita, Takeji Umemura, Masanori Abe, Akinobu Takaki, Kazumichi Abe, Masaaki Takamura, Tadashi Namisaki, Yuki Kugiyama, Atsumasa Komori, Atsushi Tanaka   +17 more
wiley   +1 more source

Pre-emptive TIPS in high-risk acute variceal bleeding. An updated and revised individual patient data meta-analysis

Background and Aims: A previous individual patient data meta-analysis (IPD-MA) showed that compared with drugs+endoscopy, the placement of transjugular portosystemic shunt within 72 hours of admission (pre-emptive transjugular intrahepatic portosystemic ...
Primignani, Massimo, Li, Yingchun, Casanovas, Georgina, Nevens, Frederik, Mundi, Jose Luis, Appenrodt, Beate, Silva-Junior, Gilberto, Zhao, Jianbo, Nicoarǎ-Farcǎu, Oana, He, Chuangye, Ren, Weixin, Zhang, Chunqing, Ibañez-Samaniego, Luis, Jiang, Zaibo, Amitrano, Lucio, Genescà, Joan, Ferreira, Carlos Noronha, Krag, Aleksander, Jansen, Christian, García-Pagán, Juan C., Zhong, Jiawei, Palazon, Jose Maria, Zhuge, Yuzheng, Han, Guohong, Zhang, Ming, Mössner, Joachim, Buceta, Enrique, Ferlitsch, Arnulf, Ding, Pengxu, Wang, Guangchuan, Bureau, Christophe, Hernández-Gea, Virginia, Dunne, Philip D.J., Thabut, Dominique, Ruiz-Del-Arbol, Luis, Fan, Daiming, Caca, Karel, Pena, Elena, Procopet, Bogdan, Castellot, Ana, Dell'Era, Alessandra, Ma, Fuquan, Peng, Qifeng, Monescillo Francia, Alberto Fernando, Xue, Hui, Zhang, Wenguang, Bosch, Jaime, Llop, Elba, Dong, Junjiao, Di Pascoli, Marco, Sauerbruch, Tilman, Calleja, Jose Luis, Albillos, Agustin, Cañete, Nuria, Castellote, Jose, Hernández-Guerra, Manuel, Nicuesa Martínez, Javier, Casas, Meritxell, Robic, Marie Angèle, Romero-Gómez, Manuel, Masnou, Helena, Trebicka, Jonel, Alvarado, Edilmar, Sierra, Angel, Rudler, Marika, Angrisani, Debora, Guevara, Clemencia, Sanchez, Juan, Tantau, Marcel, Sun, Minhuang, Zuo, Luo, Hayes, Peter C., Torres, Ferran, Abraldes, Juan G., Vinel, Jean Pierre, Martinez-Lagares, Francisco, Barcelo, Rafael, Zhang, Kewei, Villanueva, Candid, Marrero, Jose Miguel, Luca, Angelo, Laleman, Wim, Conejo, Irene, Sun, Junhui, Cruz, Ana, Senzolo, Marco, Zhu, Xuan, Gluud, Lise L., Zipprich, Alexander, Catalina, Maria Vega, Rodrigues, Susana, Gronbaek, Henning, Jimenez, Elena, Rodríguez, Manuel, Sassatelli, Romano, Luo, Junyang, Lv, Yong, Penate, Monica, Giráldez, Álvaro, Guardascione, Maria Anna   +99 more
core   +1 more source

Recombinant ADAMTS13 Ameliorates Liver Injury and Improves Hepatic Microcirculation in a Murine Acute‐on‐Chronic Liver Failure Model

Hepatology Research, EarlyView.
ABSTRACT Aim The therapeutic significance of recombinant a disintegrin‐like and metalloprotease with thrombospondin type 1 motif 13 (rADAMTS13) in acute‐on‐chronic liver failure (ACLF) remains unclear. We aimed to investigate the therapeutic effects of rADAMTS13 in a murine model of ACLF‐like liver injury.
Jun‐ichi Hanatani, Norihisa Nishimura, Kosuke Kaji, Masayoshi Takami, Hiroyuki Masuda, Hiroaki Takaya, Koh Kitagawa, Shinya Sato, Tadashi Namisaki, Hitoshi Yoshiji   +9 more
wiley   +1 more source

Is Doppler Ultrasonography Useful in Assessing Risk of Variceal Bleeding? [PDF]

, 2000
Background/Aims : Prediction of variceal bleeding has been based on the large variceal size and the red color sign observed during endoscopy. By comparing the characteristic hemodynamic features of Doppler ultrasonography between liver cirrhosis patients
이동기
core