Results 161 to 170 of about 3,471,986 (360)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Genome-Wide Dissection of Selection on microRNA Target Genes Involved in Rice Flower Development

open access: yesPlants
Although genome-wide studies have identified a number of candidate regions evolving under selection in domesticated animals and cultivated plants, few attempts have been made, from the point of a definite biological process, to assess sequence variation ...
Fen Zhang, Li-Zhen Ling, Li-Zhi Gao
doaj   +1 more source

On Higher Syzygies of Projective Toric Varieties

open access: yes, 2006
Let A be an ample line bundle on a projective toric variety X of dimension n (≥ 2). It is known that the d-th tensor power A⊗d embedds X as a projectively normal variety in Pr := P(H0(X,L⊗d)) if d ≥ n − 1.
Shoetsu Ogata, Ogata, Shoetsu
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Developing Transferable Fourier Transform Mid-Infrared Spectroscopy Predictive Models for Buffalo Milk: A Spatio-Temporal Application Strategy Analysis Across Dairy Farms

open access: yesFoods
A robust model of buffalo milk based on Fourier Transform Mid-Infrared Spectroscopy (FT-MIRS) is lacking and is difficult to complete quickly. Therefore, this study used 614 milk samples from two buffalo farms from south and central China for FT-MIRS to ...
Han Jiang   +12 more
doaj   +1 more source

Curves in Hilbert modular varieties

open access: yes, 2016
We study curves in Hilbert modular varieties from the point of view of the Green-Gri\0ths-Lang conjecture claiming that entire curves in complex projective varieties of general type should be contained in a proper subvariety. Using holomorphic foliations
Rousseau, Erwan
core  

Performance of small grain varieties for forage in Alabama, 2004-05 [PDF]

open access: yes, 2005
Caption title: 2004 [sic: 2005] Alabama Performance Comparison of Small Grain Varieties for Forage. Cover title: Performance of small grain varieties for forage in Alabama, 2004-05. "July 2005.
Van Santen, Edzard, Glass, Kathryn M.
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

ON THE QUOTIENT VARIETY OF AN ABELIAN VARIETY [PDF]

open access: yesProceedings of the National Academy of Sciences, 1952
openaire   +2 more sources

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