Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Editorial: Breeding for intercropping, volume II. [PDF]
Hohmann P, Weih M, Rubiales D.
europepmc +1 more source
Assortment Variety: Attribute versus Product-Based [PDF]
Retailers need to decide on the content and structure of their product assortments, and thereby on the degree of variety that they offer to their customers.This paper compares measures of assortment variety and relates them to underlying variety ...
Herpen, H.W.I. van, Pieters, R.
core
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
<i>When</i>, <i>How</i>, and <i>If</i> Intelligence Testing Matters for Academic Achievement. [PDF]
Frey MC, Niileksela CR.
europepmc +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Effect of Order of Testing on Intraocular Pressure and Tear Production Measurement in Dogs. [PDF]
Keenen KR, Keenen D, Adkins E.
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Lightweight CNN and transformer detectors for real-time single-fruit date-variety recognition on edge GPU hardware. [PDF]
Miski A, Alshangiti M.
europepmc +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source

