Results 91 to 100 of about 5,187,501 (361)

Circulatory contributors to the phenotype in hereditary hemorrhagic telangiectasia [PDF]

open access: yes, 2015
Hereditary hemorrhagic telangiectasia (HHT) is mechanistically and therapeutically challenging, not only because of the molecular and cellular perturbations that generate vascular abnormalities, but also the modifications to circulatory physiology that ...
Shovlin, CL
core   +2 more sources

Progression of endothelial dysfunction, atherosclerosis, and arterial stiffness in stable kidney transplant patients: a pilot study. [PDF]

open access: yes, 2020
BACKGROUND: Kidney transplant patients suffer from vascular abnormalities and high cardiovascular event rates, despite initial improvements post-transplantation. The nature of the progression of vascular abnormalities in the longer term is unknown.
Banerjee, D   +5 more
core   +1 more source

Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms

open access: yesCanadian Journal of Cardiology, 2017
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
J. Petrie, T. Guzik, R. Touyz
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Soluble Epoxide Hydrolase Inhibitor AR9281 Decreases Blood Pressure, Ameliorates Renal Injury and Improves Vascular Function in Hypertension

open access: yesPharmaceuticals, 2009
Soluble epoxide hydrolase inhibitors (sEHIs) are demonstrating promise as potential pharmaceutical agents for the treatment of cardiovascular disease, diabetes, inflammation, and kidney disease. The present study determined the ability of a first-inclass
Sean Shaw   +2 more
doaj   +1 more source

Morphological and morphometrical aspects of intima and media of the common, external and internal iliac arteries in Chinchilla lanigera (Rodentia, Chinchillidae) bred in captivity

open access: yesThe European Zoological Journal, 2020
The paper approaches deal with fine differential morphological and morphometrical aspects of the structure of three main blood vessels in Chinchilla lanigera: the common iliac artery, the internal iliac artery and the external iliac artery.
C. O. Martonos   +5 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Overview on the Evolution of Laser Welding of Vascular and Nervous Tissues

open access: yesApplied Sciences, 2019
Laser welding presents a core position in the health sector. This process has had an outstanding impact on the surgical procedures from many medical areas, such as on vascular and nervous surgeries.
Diogo Francisco Gomes   +2 more
doaj   +1 more source

Connexin 43 plays a role in pulmonary vascular reactivity in mice [PDF]

open access: yes, 2018
Pulmonary arterial hypertension (PAH) is a chronic condition characterized by vascular remodeling and increased vaso-reactivity. PAH is more common in females than in males (~3:1).
Andrew Shaw   +11 more
core   +1 more source

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