The myeloproliferative neoplasms (MPN), a heterogeneous group of disorders characterized by specific genetic mutations, have the development of arterial and venous thrombosis as their main complication.
Anca Drăgan +5 more
doaj +1 more source
Hemangiopericytoma - The need for a protocol-based treatment plan
Hemangiopericytoma is a vascular tumor which comprises only 1% of all vascular tumors. The frequency of occurrence in the head and neck accounts for about 16-33% of all hemangiopericytomas.
Murugesan Krishnan +2 more
doaj +1 more source
The Current State of Vascular Surgery Presence in Bilibili Video Platform of China
BackgroundWith the development of the Internet, more and more patients search for disease-related information on video platforms during the treatment process, and physicians also look for learning materials through these video platforms.
Haoliang Wu +14 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Vascular risk and depression in outpatients at Groote Schuur Hospital memory clinic [PDF]
Includes bibliographical references (leaves 59-67).Background and Objective: Depression in the elderly has been linked with stroke, and with white matter lesions, particularly in frontal-subcortical regions responsible for mood regulation.
Kinnear, H
core +1 more source
Case Report: Decoding genetic risks of vascular parkinsonism: a case series
BackgroundVascular parkinsonism (VaP) is a subtype of parkinsonism which needs better characterization of its risks and determinants.ObjectiveThe aim of this report is to present an understanding of genetic risks of vascular parkinsonism.MethodsFive ...
Ali Shalash +8 more
doaj +1 more source
The formation of new blood vessel networks occurs via angiogenesis during development, tissue repair, and disease. Angiogenesis is regulated by intracellular endothelial signalling pathways, induced downstream of vascular endothelial growth factors ...
Kazuhide S Okuda +11 more
doaj +1 more source
Reply to Eker et al. Comment on Kilian et al. Comparing Characteristics and Treatment of Brain Vascular Malformations in Children and Adults with HHT. J. Clin. Med. 2023, 12, 2704. [PDF]
We are grateful to Eker et al. for their thoughtful analysis and response to our publication titled Comparing Characteristics and Treatment of Brain Vascular Malformations in Children and Adults with HHT [...]
The Brain Vascular Malformation Consortium HHT Investigator Group, +29 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Role of Vascular-Immune Interactions in Modulating Chemotherapy Induced Neuropathic Pain
Chemotherapy causes sensory disturbances in cancer patients that results in neuropathies and pain. As cancer survivorships has dramatically increased over the past 10 years, pain management of these patients is becoming clinically more important. Current
Tameille Valentine +4 more
doaj +1 more source

