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Vascular Calcification

2002
Vascular calcification is a pathological calcification process. Its pathogenesis involves active mineralization by chondrogenic and osteogenic cells. Since cartilaginous metaplasia has been found in several vascular diseases, this process may represent one of vascular remodeling in response to vascular injury.
openaire   +2 more sources

Warfarin and Vascular Calcification

The American Journal of Medicine, 2016
The vitamin K antagonist, warfarin, is the most commonly prescribed oral anticoagulant. Use of warfarin is associated with an increase in systemic calcification, including in the coronary and peripheral vasculature. This increase in vascular calcification is due to inhibition of the enzyme matrix gamma-carboxyglutamate Gla protein (MGP).
Timothy J, Poterucha   +1 more
openaire   +2 more sources

Mechanisms of Vascular Calcification

Advances in Chronic Kidney Disease, 2007
Vascular calcification is highly prevalent and correlated with high rates of cardiovascular mortality in chronic kidney disease patients. Recent evidence suggests that mineral, hormonal, and metabolic imbalances that promote phenotype change in vascular cells as well as deficiencies in specific mineralization inhibitory pathways may be important ...
Mohga, El-Abbadi, Cecilia M, Giachelli
openaire   +2 more sources

Vascular calcification

2015
Abstract Vascular calcification (VC) is a common feature of patients with advanced CKD and it could be, at least in part, the cause of increased cardiovascular mortality in these patients. From a morphologic point of view, there are at least two types of pathologic calcium phosphate deposition in the arterial wall—namely, intima ...
Adrian Covic   +3 more
openaire   +1 more source

Circulating uromodulin inhibits vascular calcification by interfering with pro-inflammatory cytokine signaling.

Cardiovascular Research, 2020
AIMS Uromodulin is produced exclusively in the kidney and secreted into both urine and blood. Serum levels of uromodulin are correlated with kidney function and reduced in chronic kidney disease (CKD) patients, but physiological functions of serum ...
I. Alesutan   +21 more
semanticscholar   +1 more source

SGLT2 inhibitor canagliflozin alleviates vascular calcification through suppression of NLRP3 inflammasome.

Cardiovascular Research, 2023
An Chen   +14 more
semanticscholar   +1 more source

Vascular Calcifications

2018
Abstract Vascular calcifications lie within the artery wall, and appear to be linear, usually in association with blood vessels. The parallel or “tram-track” appearance of the calcifications in opposite walls of the artery is pathognomonic. They are more prevalent with age.
openaire   +1 more source

Calcium intake, vascular calcification, and vascular disease

Nutrition Reviews, 2013
Recent research has reported a possible link between calcium supplementation and increased risk of cardiovascular disease and its endpoints in healthy, older adults. To evaluate the current evidence regarding the impact of calcium supplementation on cardiovascular disease risk and to address research gaps, the present review was conducted.
Lisa A, Spence, Connie M, Weaver
openaire   +2 more sources

An update on vascular calcification and potential therapeutics

Molecular Biology Reports, 2021
Anubha Singh, S. Tandon, C. Tandon
semanticscholar   +1 more source

Oxidative Stress in Vascular Calcification.

Clinica chimica acta; international journal of clinical chemistry, 2021
Chu-Ting Hu   +7 more
semanticscholar   +1 more source

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