Results 1 to 10 of about 2,150,532 (298)

Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundDespite recent improvements in angioplasty and placement of drug‐eluting stents in treatment of atherosclerosis, restenosis and in‐stent thrombosis impede treatment efficacy and cause numerous deaths. Research efforts are needed to identify new
Yufeng Yao, Zhenkun Hu, Jian Ye, Changqing Hu, Qixue Song, Xingwen Da, Yubin Yu, Hui Li, Chengqi Xu, Qiuyun Chen, Qing Kenneth Wang   +10 more
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Effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aorta

Бюллетень сибирской медицины, 2010
In preparations of rat aorta, used as a model of muscular type arteries, the method mehanografii studied the effect of hydrogen sulfide on the reduction of isolated of vascular smooth muscle.
M. B. Baskakov, S. V. Gusakova, A. S. Zheludeva, L. V. Smagly, I. V. Kovalyov, T. A. Vtorushina, D. S. Nosov, K. V. Yeryomenko, M. A. Medvedev, S. N. Orlov   +9 more
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The Bone-Vascular Axis: A Key Player in Chronic Kidney Disease Associated Vascular Calcification

Kidney Diseases
Background: The bone-vascular axis plays a key role in the pathogenesis of vascular calcification (VC) in patients with chronic kidney disease (CKD). Understanding and managing the role of the bone-vascular axis in CKD-mineral and bone disorder (CKD-MBD)
Yingjing Shen, Chen Yu
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The epigenetic basis of vascular calcification: focus on histone modifications

European Journal of Medical Research
Histone modifications, including methylation, acetylation, and phosphorylation, are increasingly recognized as key contributors to the development of vascular calcification.
Junmin Huang, Changheng Li, Yunan Wang, Zekun Zhong, Tongtong Ma, Lu Chen, Hongying Luo, Ziqian Bi, Tianyang Wang, Huafeng Liu, Junfeng Hao, Peng Wang, Yongzhi Xu   +12 more
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Dipeptidyl peptidase-4 inhibitor gemigliptin protects against vascular calcification in an experimental chronic kidney disease and vascular smooth muscle cells.

PLoS ONE, 2017
Although dipeptidyl peptidase-4 inhibitors, a class of antidiabetic drugs, have various pleiotropic effects, it remains undetermined whether gemigliptin has a beneficial effect on vascular calcification.
Soon-Youn Choi, Hye-Myung Ryu, Eun-Joo Oh, Ji-Young Choi, Jang-Hee Cho, Chan-Duck Kim, Yong-Lim Kim, Sun-Hee Park   +7 more
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Specialized mouse embryonic stem cells for studying vascular development

Stem Cells and Cloning: Advances and Applications, 2014
Drew E Glaser,1 Andrew B Burns,2 Rachel Hatano,2 Magdalena Medrzycki,3 Yuhong Fan,3 Kara E McCloskey1 1School of Engineering, University of California, Merced, CA, USA; 2School of Natural Sciences, University of California, Merced, CA, USA; 3School of ...
Glaser DE, Burns AB, Hatano R, Medrzycki M, Fan Y, McCloskey KE   +5 more
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Somatic PDGFRB activating variants promote smooth muscle cell phenotype modulation in intracranial fusiform aneurysm

Journal of Biomedical Science
Background The fusiform aneurysm is a nonsaccular dilatation affecting the entire vessel wall over a short distance. Although PDGFRB somatic variants have been identified in fusiform intracranial aneurysms, the molecular and cellular mechanisms driving ...
Li Hao, Xiaolong Ya, Jiaye Wu, Chuming Tao, Ruochen Ma, Zhiyao Zheng, Siqi Mou, Yiming Ling, Yingxi Yang, Jiguang Wang, Yan Zhang, Qing Lin, Jizong Zhao   +12 more
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NKX2-5 regulates vessel remodeling in scleroderma-associated pulmonary arterial hypertension

JCI Insight
NKX2-5 is a member of the homeobox-containing transcription factors critical in regulating tissue differentiation in development. Here, we report a role for NKX2-5 in vascular smooth muscle cell phenotypic modulation in vitro and in vascular remodeling ...
Ioannis Papaioannou, Athina Dritsoula, Ping Kang, Reshma S. Baliga, Sarah L. Trinder, Emma Cook, Xu Shiwen, Adrian J. Hobbs, Christopher P. Denton, David J. Abraham, Markella Ponticos   +10 more
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Role of α‐SMA, NOX4, Fibronectin, and HIF‐1α in Pulmonary Microvascular Remodeling in COPD Patients Without Pulmonary Arterial Hypertension

The Clinical Respiratory Journal
Background Pulmonary arterial hypertension (PAH) is a severe chronic obstructive pulmonary disease (COPD) complication, with vascular remodeling occurring early in disease progression.
Guo Xiaotong, Fan Yuchun, Ji Ting, Cao Xia, Jiang Haifeng, Chen Juan, Xin Hongxia   +6 more
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Exosomal micro ribonucleic acid-154-5p derived from vascular smooth muscle cell mediates intracranial aneurysm phenotype in vitro via myosin light chain kinase targeting

Journal of International Medical Research
Objective The molecular pathogenesis of intracranial aneurysms remains undefined despite its central role in aneurysmal subarachnoid hemorrhage, a major cause of stroke and shock.
Jinhai Song, Wenkang Luan, Liang Chu, Pengjie Pan, Yao Qian, Yunpeng Lu   +5 more
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