Results 31 to 40 of about 2,150,532 (298)

Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries. [PDF]

open access: yes, 2012
Vascular interstitial cells (VICs) are non-contractile cells with filopodia previously described in healthy blood vessels of rodents and their function remains unknown.
Reddy, M   +10 more
core   +1 more source

α-Smooth Muscle Actin and ACTA2 Gene Expressions in Vasculopathies

open access: yesBrazilian Journal of Cardiovascular Surgery, 2015
α-smooth muscle actin, encoded by ACTA2 gene, is an isoform of the vascular smooth muscle actins, typically expressed in the vascular smooth muscle cells contributing to vascular motility and contraction. ACTA2 gene mutations cause a diversity of diffuse
Shi-Min Yuan
doaj   +1 more source

Dietary salt initiates redox signaling between endothelium and vascular smooth muscle through NADPH oxidase 4

open access: yesRedox Biology, 2022
Prevention of phenotype switching of vascular smooth muscle cells is an important determinant of normal vascular physiology. Hydrogen peroxide (H2O2) promotes osteogenic differentiation of vascular smooth muscle cells through expression of Runt related ...
Kai er Ying   +7 more
doaj   +1 more source

Vascular Smooth Muscle Updated [PDF]

open access: yesCirculation Research, 1973
• This brief review of the rapidly developing research on vascular smooth muscle presents the state of the art as I see it from within my own frame of reference. For a more objective, detailed insight into the workings of vascular smooth muscle, several substantial reviews and compendiums may be read (1-7).
openaire   +2 more sources

Notch signaling pathway in human vascular smooth muscle cell differentiation [PDF]

open access: yes, 2006
Notch receptor-ligand interactions are a highly conserved mechanism, originally described in developmental studies using Drosophilae, that regulate inter-cell communication and dictate, in part, vascular smooth muscle cell (VSMC) fate in response to ...
Scheller, Agnieszka
core   +2 more sources

Smooth muscle cells and vascular diseases [PDF]

open access: yesCardiovascular Research, 2012
Vascular smooth muscle cells (VSMCs) are the stromal cells of the vascular wall, and, due to their myosin/actin interactions, they are also responsible for arterial contractile tonus and regulating blood pressure and flow in relation to specific metabolic demands.
Jean-Baptiste, Michel   +2 more
openaire   +2 more sources

Lack of α8 integrin leads to morphological changes in renal mesangial cells, but not in vascular smooth muscle cells

open access: yesBMC Cell Biology, 2010
Background Extracellular matrix receptors of the integrin family are known to regulate cell adhesion, shape and functions. The α8 integrin chain is expressed in glomerular mesangial cells and in vascular smooth muscle cells.
Hilgers Karl F   +9 more
doaj   +1 more source

Highly effective non-viral gene transfer into vascular smooth muscle cells of cultured resistance arteries demonstrated by genetic inhibition of sphingosine-1-phosphate-induced vasoconstriction [PDF]

open access: yes, 2003
The linkage of vascular genes to specific functions will lead to a better understanding of cardiovascular pathophysiology. We developed an experimental model that enables the introduction of one or multiple gene(s) into vascular smooth muscle cells ...
Pohl, U., Bolz, S. S.
core   +2 more sources

Mebendazole reduces vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice.

open access: yesPLoS ONE, 2014
Mebendazole is an antihelminthic drug that exerts its effects via interference with microtubule function in parasites. To determine the utility of mebendazole as a potential treatment for vascular diseases involving proliferation of vascular smooth ...
Jintao Wang   +8 more
doaj   +1 more source

Endothelial cell-derived extracellular vesicles alter vascular smooth muscle cell phenotype through high-mobility group box proteins

open access: yesJournal of Extracellular Vesicles, 2020
The vascular endothelium and smooth muscle form adjacent cellular layers that comprise part of the vascular wall. Each cell type can regulate the other’s structure and function through a variety of paracrine effectors.
Michael J. Boyer   +7 more
doaj   +1 more source

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