Results 91 to 100 of about 289,601 (306)

Soluble adhesion molecules and angiotensin-converting enzyme in dementia

Neurobiology of Disease, 2007
We aimed to determine plasma and cerebrospinal fluid (CSF) levels of angiotensin-converting enzyme (ACE) and the soluble forms of intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1) and platelet endothelial cell ...
Henrietta M. Nielsen, Elisabet Londos, Lennart Minthon, Sabina M. Janciauskiene   +3 more
doaj   +1 more source

Persistent inflammation and endothelial activation in HIV-1 infected patients after 12 years of antiretroviral therapy. [PDF]

PLoS ONE, 2013
The study investigated markers of inflammation and endothelial activation in HIV infected patients after 12 years of successful combination antiretroviral treatment (cART).Inflammation and endothelial activation were assessed by measuring levels of ...
Frederikke F Rönsholt, Henrik Ullum, Terese L Katzenstein, Jan Gerstoft, Sisse R Ostrowski   +4 more
doaj   +1 more source

The role of cellular adhesion molecules in virus attachment and entry [PDF]

, 2015
As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome.
Bhella, David
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Association of adipokines and adhesion molecules with indicators of obesity in women undergoing mammography screening

Nutrition & Metabolism, 2012
Background The soluble cell adhesion molecules and adipokines are elevated in patients with obesity, hypertension, type 2 diabetes mellitus, breast cancer and atherosclerosis.
Isoppo de Souza Caroline, Rosa Daniela Dornelles, Ettrich Betina, Cibeira Gabriela Hermann, Giacomazzi Juliana, Tusset Paloma, Ashton-Prolla Patrícia, Medeiros Lidia Rosi, Caleffi Maira, Neto Eurico Camargo, Moriguchi Emilio Hideyuki, Graudenz Marcia Silveira   +11 more
doaj   +1 more source

Expression of cell adhesion in molecules in murine placentas and a placental cell line [PDF]

, 1999
Integrins and vascular cell adhesion molecule-1 (VCAM-1) are required for normal placental development. In this study, integrin subunits α4, αv, β1, and β3, and VCAM-1 were investigated for expression in uteroplacental units (gestation day [g.d.] 6 and 8)
Bowen, Jeffery, Hunt, J. S.
core   +1 more source

VEGF(164)-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization [PDF]

, 2003
Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted.
Adamis, AP, Amano, S, Ambati, J, D'Amore, PA, Gragoudas, ES, Hida, T, Ishida, S, Kaji, Y, Miller, JW, Ng, YS, Oguchi, Y, Ogura, Y, Shima, DT, Usui, T, Yamashiro, K   +14 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice [PDF]

, 2013
Type 1 diabetes (T1D) results from the autoimmune destruction of insulin-producing beta-cells in the pancreas. Recruitment of inflammatory cells is prerequisite to beta-cell-injury.
Aurrand-Lions, Michel, Bayer, Monika, Christen, Selina, Christen, Urs, Coppieters, Ken, Herrath, Matthias G. von, Hintermann, Edith, Holdener, Martin, Imhof, Beat A., Pfeilschifter, Josef Martin (Prof. Dr.), Rose, Kerstin   +10 more
core   +3 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source