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Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1

Nature, 2005
Increased expression of vascular cell adhesion molecule 1 (VCAM1) is associated with a variety of chronic inflammatory conditions, making its expression and function a target for therapeutic intervention. We have recently identified CAM741, a derivative of a fungus-derived cyclopeptolide that acts as a selective inhibitor of VCAM1 synthesis in ...
Jürgen, Besemer   +9 more
openaire   +2 more sources

Vascular Cell Adhesion Molecule-1 (VCAM-1)

2016
Expressed on activated endothelial cells, vascular cell adhesion molecule-1 (VCAM-1) is an immunoglobulin-like adhesion molecule. It is not expressed under baseline conditions; however it is quickly induced in response to inflammatory stimuli, such as the cytokines tumour necrosis factor and in proatherosclerotic conditions including in early lesions ...
openaire   +1 more source

Vascular Cell Adhesion Molecule-1

1991
Roy Lobb   +2 more
openaire   +1 more source

αdβ2 Integrin Is a Ligand for Vascular Cell Adhesion Molecule–1

International Archives of Allergy and Immunology, 1999
M H, Grayson   +6 more
openaire   +2 more sources

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