Intravitreal Anti-VEGF Drugs and Signals of Dementia and Parkinson-Like Events: Analysis of the VigiBase Database of Spontaneous Reports [PDF]
, 2020 Introduction: Since vascular endothelial growth factor (VEGF) regulates several aspects of the central nervous system, particularly in dopaminergic neurons, VEGF inhibitors may be linked to Parkinson-like events and dementia, or variants of these ...
Avery +30 more
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Walking on the tightrope: the shared roles of the bridging pericytes in the brain
Frontiers in Cellular NeuroscienceThe vasculature of the central nervous system (CNS) is a highly specialized structure that delivers oxygen and nutrients to energy-demanding neural cells while protecting them from the toxicity of blood-borne substances.
Audrey Chagnot +5 more
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Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review. [PDF]
, 2019 As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimer's disease (AD) pathology may manifest
Honma, Patrick +2 more
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Interactive effects of vascular risk burden and advanced age on cerebral blood flow. [PDF]
, 2014 Vascular risk factors and cerebral blood flow (CBF) reduction have been linked to increased risk of cognitive impairment and Alzheimer's disease (AD); however the possible moderating effects of age and vascular risk burden on CBF in late life remain ...
Bangen, Katherine J +10 more
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Association of N-terminal pro-brain natriuretic peptide with cognitive function and depression in elderly people with type 2 diabetes [PDF]
, 2012 <p>Background: Type 2 diabetes mellitus is associated with risk of congestive heart failure (CHF), cognitive dysfunction and depression. CHF itself is linked both to poor cognition and depression.
, +7 more
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Investigation into the vascular contributors to dementia and the associated treatments
Exploration of Neuroscience, 2023 As the average lifespan has increased, memory disorders have become a more pressing public health concern. However, dementia in the elderly population is often neglected in light of other health priorities.
Caroline Grace Davidson +7 more
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Alzheimer and vascular brain diseases: Focal and diffuse subforms. [PDF]
, 2015 Alois Alzheimer is best known for his description of the pre-senile neurodegenerative disease named after him. However, his previous interest in vascular brain diseases, underlying cognitive and behavioral changes, was very strong. Besides describing the
Engelhardt, Eliasz, Grinberg, Lea T
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Alzheimer and vascular brain disease: Senile dementia. [PDF]
, 2015 Alois Alzheimer is best known for his description of a novel disease, subsequently named after him. However, his wide range of interests also included vascular brain diseases.
Engelhardt, Eliasz, Grinberg, Lea T
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An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis
Nature CommunicationsAtherosclerosis is the underlying cause of myocardial infarction and ischemic stroke. It is a lipid-triggered and cytokine/chemokine-driven arterial inflammatory condition.
Omar El Bounkari +36 more
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Diagnosis in vascular dementia, applying ‘Cochrane diagnosis rules’ to ‘dementia diagnostic tools’ [PDF]
, 2017 In this issue of Clinical Science, Biesbroek and colleagues describe recent work on magnetic resonance imaging (MRI)-based cerebral lesion location and its association with cognitive decline.
McCleery, Jenny, Quinn, Terence J.
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