Results 21 to 30 of about 11,970,410 (409)

Protein engineering to develop a redox insensitive endothelial nitric oxide synthase

Redox Biology, 2014
The zinc tetrathiolate (ZnS4) cluster is an important structural feature of endothelial nitric oxide synthase (eNOS). The cluster is located on the dimeric interface and four cysteine residues (C94 and C99 from two adjacent subunits) form a cluster with ...
Ruslan Rafikov, Sanjiv Kumar, Saurabh Aggarwal, Daniel Pardo, Fabio V. Fonseca, Jessica Ransom, Olga Rafikova, Qiumei Chen, Matthew L. Springer, Stephen M. Black   +9 more
doaj   +1 more source

Rheopheresis in vascular diseases [PDF]

Clinical Hemorheology and Microcirculation, 2017
Rheopheresis is an extracorporal selective double-filtration procedure. In the first part of the treatment the blood is passes through the plasma filter, which separates blood cells from the plasma. Then the plasma flow to a second filter called MONET (Membranefiltration Optimised Novel Extracorporal Treatment).
Vass, Melinda, Diószegi, Ágnes, Németh, Norbert, Somogyi, Viktória, Baráth, Sándor, Szalai, Eszter, Módis, László, Soltész, Pál   +7 more
openaire   +3 more sources

Drug treatment of hypertension: focus on vascular health [PDF]

, 2016
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C., Lang, Ninian N., Touyz, Rhian M.   +2 more
core   +1 more source

Sex Differences in Stroke Subtypes, Severity, Risk Factors, and Outcomes Among Elderly Patients with Acute Ischemic Stroke

Frontiers in Aging Neuroscience, 2015
Background: Although the age-specific incidence and mortality of stroke is higher among men, stroke has a greater clinical effect on women. However, the sex differences in stroke among elderly patients are unknown.
Changshen eYu, Zhongping eAn, Wenjuan eZhao, Wanjun eWang, Chunlin eGao, Shoufeng eLiu, Jinghua eWang, Jialing eWu   +7 more
doaj   +1 more source

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.

New England Journal of Medicine, 2020
BACKGROUND Progressive respiratory failure is the primary cause of death in the coronavirus disease 2019 (Covid-19) pandemic. Despite widespread interest in the pathophysiology of the disease, relatively little is known about the associated morphologic ...
M. Ackermann, S. Verleden, M. Kuehnel, A. Haverich, T. Welte, F. Laenger, A. Vanstapel, C. Werlein, Helge Stark, A. Tzankov, William Li, V. Li, S. Mentzer, D. Jonigk   +13 more
semanticscholar   +1 more source

Pregnancy complications and maternal cardiovascular risk: opportunities for intervention and screening? [PDF]

, 2002
The link between defective nutrition of the fetus and vascular disease in later life is now well established. Naveed Sattar and Ian Greer report on the intriguing probability that complications in pregnancy also predispose mothers to later vascular and ...
Greer, I., Sattar, N.
core   +2 more sources

Blood pressure variability and cardiovascular risk in the PROspective study of pravastatin in the elderly at risk (PROSPER) [PDF]

, 2012
Variability in blood pressure predicts cardiovascular disease in young- and middle-aged subjects, but relevant data for older individuals are sparse. We analysed data from the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) study of ...
A Frattola, AJ Webb, Anton J. M. de Craen, AV Chobanian, C Geeganage, Christopher J. Packard, David J. Stott, E O'Brien, E Pringle, G Mancia, G Parati, G Parati, I Ford, Ian Ford, J Shepherd, J Shepherd, J. Wouter Jukema, Jacobijn Gussekloo, JS Grove, K Keenan, M Kikuya, M Tozawa, Naveed Sattar, OH Klungel, P Muntner, PM Rothwell, PM Rothwell, PM Rothwell, RJ Havlik, RL Cuffe, Robert Clarke, Rosalinde K. E. Poortvliet, Rudi G. J. Westendorp, S Lewington, SC Howard, Simon P. Mooijaart, Suzanne M. Lloyd, T Marshall, TG Pickering, Wouter de Ruijter, Y Hata, Y Hata   +41 more
core   +7 more sources

Long‐Term Outcomes of Patients With Mediastinal Radiation–Associated Severe Aortic Stenosis and Subsequent Surgical Aortic Valve Replacement: A Matched Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundCardiac disease after mediastinal radiotherapy for thoracic malignancy (chest radiotherapy [XRT]) often manifests as progressive aortic stenosis.
Eoin Donnellan, Ahmad Masri, Douglas R. Johnston, Gosta B. Pettersson, L. Leonardo Rodriguez, Zoran B. Popovic, Eric E. Roselli, Nicholas G. Smedira, Lars G. Svensson, Brian P. Griffin, Milind Y. Desai   +10 more
doaj   +1 more source

Oral contraception and eye disease: findings in two large cohort studies [PDF]

, 1997
AIM : To investigate the relation between oral contraceptive use and certain eye diseases. \ud \ud METHODS : Abstraction of the relevant data from the two large British cohort studies of the effects of oral contraception, the Royal College of General ...
Chappell, D., Frith, P., Hannaford, P., Mant, J.W.F., Painter, R., Vessey, M.P.   +5 more
core   +2 more sources

Autophagy in Vascular Disease [PDF]

Circulation Research, 2015
Autophagy is a reparative, life-sustaining process by which cytoplasmic components are sequestered in double-membrane vesicles and degraded on fusion with lysosomal compartments. Growing evidence reveals that basal autophagy is an essential in vivo process mediating proper vascular function.
G. D. De Meyer, M. Grootaert, Cédéric F. Michiels, A. Kurdi, D. Schrijvers, W. Martinet   +5 more
semanticscholar   +5 more sources