Results 21 to 30 of about 64,967 (266)

Evaluate the Correlation between the TIMI Frame Count, IMR, and CFR in Coronary Microvascular Disease

Journal of Interventional Cardiology, 2022
Objective. To evaluate the correlation between the TIMI frame count, IMR, and CFR in coronary microvascular disease (slow flow phenomenon). Methods.
Xinye Xu, Jinbao Zhou, Yongzhen Zhang, Qian Li, Lijun Guo, Yanyang Mao, Liyun He   +6 more
doaj   +1 more source

Safety and efficacy of larval therapy on treating leg ulcers: a protocol for systematic review and meta-analysis

BMJ Open, 2020
Introduction Leg ulcers (LUs) not only seriously affect life and work of patients, but also bring huge economic burden to the society. As a potential underused biological debridement, larval therapy provides help for the treatment of LUs.
Xiao Yang, Weijing Fan, Baozhong Yang, Xiaoming Hu, Chenyan Shi, Guobin Liu   +5 more
doaj   +1 more source

Pharmacological Targeting of the RAGE-NFκB Signalling Axis Impedes Monocyte Activation under Diabetic Conditions through the Repression of SHP-2 Tyrosine Phosphatase Function

Cells, 2023
Monocytes play a vital role in the development of cardiovascular diseases. Type 2 diabetes mellitus (T2DM) is a major CVD risk factor, and T2DM-induced aberrant activation and enhanced migration of monocytes is a vital pathomechanism that leads to ...
Marc Dorenkamp, Madina Nasiry, Dilvin Semo, Sybille Koch, Ivonne Löffler, Gunter Wolf, Holger Reinecke, Rinesh Godfrey   +7 more
doaj   +1 more source

In patients with superficial vein thrombosis the inflammatory response is increased and related to the recanalization rate

Archives of Medical Science, 2019
Introduction Little is known about pathogenetic mechanisms of superficial venous thrombosis (SVT). We aimed to investigate the systemic inflammatory response in the acute phase of SVT, the time course of inflammatory markers and involvement of ...
Pavel Poredoš, Ana Spirkoska, Mateja Kaja Ježovnik   +2 more
doaj   +1 more source

Prognostic role of MUC5B rs35705950 genotype in patients with idiopathic pulmonary fibrosis (IPF) on antifibrotic treatment

Respiratory Research, 2021
Background A common variant located in the promoter region of MUC5B (rs35705950) is the strongest risk factor for sporadic and familiar IPF, as well as a predictor of outcome.
Davide Biondini, Elisabetta Cocconcelli, Nicol Bernardinello, Giulia Lorenzoni, Chiara Rigobello, Sara Lococo, Gioele Castelli, Simonetta Baraldo, Manuel G. Cosio, Dario Gregori, Marina Saetta, Elisabetta Balestro, Paolo Spagnolo   +12 more
doaj   +1 more source

Clinical Applications of Endobronchial Ultrasound (EBUS) Scope: Challenges and Opportunities

Diagnostics, 2023
Endobronchial Ultrasound (EBUS) has been widely used to stage lung tumors and to diagnose mediastinal diseases. In the last decade, this procedure has evolved in several technical aspects, with new tools available to optimize tissue sampling and to ...
Davide Biondini, Mariaenrica Tinè, Umberto Semenzato, Matteo Daverio, Francesca Scalvenzi, Erica Bazzan, Graziella Turato, Marco Damin, Paolo Spagnolo   +8 more
doaj   +1 more source

Apoptosis in Vascular Disease

European Journal of Vascular and Endovascular Surgery, 2001
densation and the formation of membrane-bound Since the original morphological description of apovesicles called apoptotic bodies. These are phagoptosis many molecular mechanisms that characterise cytosed by adjacent cells and macrophages without the apoptotic pathway have been identified. Apoptosis inducing an inflammatory response. In contrast, necis
A.W. Bradbury, D. Mosquera, A.G. Morris, T.C.F. Sykes   +3 more
openaire   +3 more sources

Circulating choline levels are associated with prognoses in patients with pulmonary hypertension: a cohort study

BMC Pulmonary Medicine, 2023
Backgrounds Mounting evidences have highlighted the association between metabolites and cardiovascular diseases. Our previous works have demonstrated that circulating metabolite, trimethylamine oxide, was associated with prognosis of patients with ...
Yicheng Yang, Beilan Yang, Bingyang Liu, Yanru Liang, Qin Luo, Zhihui Zhao, Zhihong Liu, Qixian Zeng, Changming Xiong   +8 more
doaj   +1 more source

Autophagy in Vascular Disease [PDF]

Circulation Research, 2015
Autophagy is a reparative, life-sustaining process by which cytoplasmic components are sequestered in double-membrane vesicles and degraded on fusion with lysosomal compartments. Growing evidence reveals that basal autophagy is an essential in vivo process mediating proper vascular function.
De Meyer, Guido R.Y., Grootaert, Mandy, Michiels, Cédéric F., Kurdi, Ammar, Schrijvers, Dorien M., Martinet, Wim   +5 more
openaire   +4 more sources

Vascular Diseases and Gangliosides [PDF]

International Journal of Molecular Sciences, 2019
Vascular diseases, such as myocardial infarction and cerebral infarction, are most commonly caused by atherosclerosis, one of the leading causes of death worldwide. Risk factors for atherosclerosis include lifestyle and aging. It has been reported that lifespan could be extended in mice by targeting senescent cells, which led to the suppression of ...
Norihiko Sasaki, Masashi Toyoda
openaire   +2 more sources