Results 21 to 30 of about 11,507,104 (364)

Long‐Term Outcomes of Patients With Mediastinal Radiation–Associated Severe Aortic Stenosis and Subsequent Surgical Aortic Valve Replacement: A Matched Cohort Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
Background Cardiac disease after mediastinal radiotherapy for thoracic malignancy (chest radiotherapy [XRT]) often manifests as progressive aortic stenosis. In patients with XRT‐induced severe aortic stenosis undergoing surgical aortic valve replacement (
Eoin Donnellan   +10 more
doaj   +1 more source

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.

open access: yesNew England Journal of Medicine, 2020
BACKGROUND Progressive respiratory failure is the primary cause of death in the coronavirus disease 2019 (Covid-19) pandemic. Despite widespread interest in the pathophysiology of the disease, relatively little is known about the associated morphologic ...
M. Ackermann   +13 more
semanticscholar   +1 more source

Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease

open access: yesAntioxidants, 2022
Oxidative stress and chronic inflammation play an important role in the pathogenesis of atherosclerosis. Atherosclerosis develops as the first step of vascular endothelial dysfunction induced by complex molecular mechanisms.
Y. Higashi
semanticscholar   +1 more source

Evaluate the Correlation between the TIMI Frame Count, IMR, and CFR in Coronary Microvascular Disease

open access: yesJournal of Interventional Cardiology, 2022
Objective. To evaluate the correlation between the TIMI frame count, IMR, and CFR in coronary microvascular disease (slow flow phenomenon). Methods.
Xinye Xu   +6 more
doaj   +1 more source

Apoptosis in Vascular Disease

open access: yesEuropean Journal of Vascular and Endovascular Surgery, 2001
densation and the formation of membrane-bound Since the original morphological description of apovesicles called apoptotic bodies. These are phagoptosis many molecular mechanisms that characterise cytosed by adjacent cells and macrophages without the apoptotic pathway have been identified. Apoptosis inducing an inflammatory response. In contrast, necis
A.W. Bradbury   +3 more
openaire   +3 more sources

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I

open access: yesEuropean Heart Journal, 2013
Hyperglycemia and insulin resistance are key players in the development of atherosclerosis and its complications. A large body of evidence suggest that metabolic abnormalities cause overproduction of reactive oxygen species (ROS).
F. Paneni   +3 more
semanticscholar   +1 more source

In patients with superficial vein thrombosis the inflammatory response is increased and related to the recanalization rate

open access: yesArchives of Medical Science, 2019
Introduction Little is known about pathogenetic mechanisms of superficial venous thrombosis (SVT). We aimed to investigate the systemic inflammatory response in the acute phase of SVT, the time course of inflammatory markers and involvement of ...
Pavel Poredoš   +2 more
doaj   +1 more source

Safety and efficacy of larval therapy on treating leg ulcers: a protocol for systematic review and meta-analysis

open access: yesBMJ Open, 2020
Introduction Leg ulcers (LUs) not only seriously affect life and work of patients, but also bring huge economic burden to the society. As a potential underused biological debridement, larval therapy provides help for the treatment of LUs.
Xiao Yang   +5 more
doaj   +1 more source

WNT Signaling in Cardiac and Vascular Disease

open access: yesPharmacological Reviews, 2018
WNT signaling is an elaborate and complex collection of signal transduction pathways mediated by multiple signaling molecules. WNT signaling is critically important for developmental processes, including cell proliferation, differentiation and tissue ...
S. Foulquier   +5 more
semanticscholar   +1 more source

Prognostic role of MUC5B rs35705950 genotype in patients with idiopathic pulmonary fibrosis (IPF) on antifibrotic treatment

open access: yesRespiratory Research, 2021
Background A common variant located in the promoter region of MUC5B (rs35705950) is the strongest risk factor for sporadic and familiar IPF, as well as a predictor of outcome.
Davide Biondini   +12 more
doaj   +1 more source

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