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Diabetic vascular diseases: molecular mechanisms and therapeutic strategies
Signal Transduction and Targeted Therapy, 2023 Vascular complications of diabetes pose a severe threat to human health. Prevention and treatment protocols based on a single vascular complication are no longer suitable for the long-term management of patients with diabetes.
Yiwen Li +7 more
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Experimental and Molecular Medicine, 2023 Senescence compromises the essential role that the endothelium plays in maintaining vascular homeostasis, so promoting endothelial dysfunction and the development of age-related vascular diseases.
Yeaeun Han, Sung Young Kim
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Eye, 2021 The angopoietin/tyrosine kinase with immunoglobulin and epidermal growth factor homology domains (Ang/Tie) pathway is an emerging key regulator in vascular development and maintenance.
A. Joussen +5 more
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Cerebral Vascular Disease [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1965 Russell Ross
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Ferroptosis of Endothelial Cells in Vascular Diseases
Nutrients, 2022 Endothelial cells (ECs) line the inner surface of blood vessels and play a substantial role in vascular biology. Endothelial dysfunction (ED) is strongly correlated with the initiation and progression of many vascular diseases. Regulated cell death, such
Hanxu Zhang +8 more
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Frontiers in Pharmacology, 2021 Traditional Chinese medicine plays a significant role in the treatment of various diseases and has attracted increasing attention for clinical applications.
Xiaopeng Ai +8 more
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MicroRNA-34a: the bad guy in age-related vascular diseases
Cellular and Molecular Life Sciences, 2021 The age-related vasculature alteration is the prominent risk factor for vascular diseases (VD), namely, atherosclerosis, abdominal aortic aneurysm, vascular calcification (VC) and pulmonary arterial hypertension (PAH).
A. Raucci +5 more
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Longevity Factor FOXO3: A Key Regulator in Aging-Related Vascular Diseases
Frontiers in Cardiovascular Medicine, 2021 Forkhead box O3 (FOXO3) has been proposed as a homeostasis regulator, capable of integrating multiple upstream signaling pathways that are sensitive to environmental changes and counteracting their adverse effects due to external changes, such as ...
Yan Zhao, Youshuo Liu
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Ventilatory efficiency in pulmonary vascular diseases
European Respiratory Review, 2021 Cardiopulmonary exercise testing (CPET) is a frequently used tool in the differential diagnosis of dyspnoea. Ventilatory inefficiency, defined as high minute ventilation (V′E) relative to carbon dioxide output (V′CO2), is a hallmark characteristic of ...
J. Weatherald +3 more
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Mitochondrial Dynamics: Pathogenesis and Therapeutic Targets of Vascular Diseases
Frontiers in Cardiovascular Medicine, 2021 Vascular diseases, particularly atherosclerosis, are associated with high morbidity and mortality. Endothelial cell (EC) or vascular smooth muscle cell (VSMC) dysfunction leads to blood vessel abnormalities, which cause a series of vascular diseases. The
Yi Luan +4 more
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