Results 1 to 10 of about 11,718,656 (303)
Engineering Organ-on-a-Chip Systems for Vascular Diseases. [PDF]
Arterioscler Thromb Vasc Biol, 2023 Vascular diseases, such as atherosclerosis and thrombosis, are major causes of morbidity and mortality worldwide. Traditional in vitro models for studying vascular diseases have limitations, as they do not fully recapitulate the complexity of the in vivo
Shakeri A +6 more
europepmc +2 more sources
Uncoupling protein 2: a key player and a potential therapeutic target in vascular diseases [PDF]
Oxidative Medicine and Cellular Longevity, 2017 Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane protein that belongs to the uncoupling protein family and plays an important role in lowering mitochondrial membrane potential and dissipating metabolic energy with prevention of oxidative ...
Forte, Maurizio +6 more
core +3 more sources
Diabetic vascular diseases: molecular mechanisms and therapeutic strategies
Signal Transduction and Targeted Therapy, 2023 Vascular complications of diabetes pose a severe threat to human health. Prevention and treatment protocols based on a single vascular complication are no longer suitable for the long-term management of patients with diabetes.
Yiwen Li +7 more
semanticscholar +1 more source
Experimental and Molecular Medicine, 2023 Senescence compromises the essential role that the endothelium plays in maintaining vascular homeostasis, so promoting endothelial dysfunction and the development of age-related vascular diseases.
Yeaeun Han, Sung Young Kim
semanticscholar +1 more source
Eye, 2021 The angopoietin/tyrosine kinase with immunoglobulin and epidermal growth factor homology domains (Ang/Tie) pathway is an emerging key regulator in vascular development and maintenance.
A. Joussen +5 more
semanticscholar +1 more source
Ferroptosis of Endothelial Cells in Vascular Diseases
Nutrients, 2022 Endothelial cells (ECs) line the inner surface of blood vessels and play a substantial role in vascular biology. Endothelial dysfunction (ED) is strongly correlated with the initiation and progression of many vascular diseases. Regulated cell death, such
Hanxu Zhang +8 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2021 Traditional Chinese medicine plays a significant role in the treatment of various diseases and has attracted increasing attention for clinical applications.
Xiaopeng Ai +8 more
semanticscholar +1 more source
MicroRNA-34a: the bad guy in age-related vascular diseases
Cellular and Molecular Life Sciences, 2021 The age-related vasculature alteration is the prominent risk factor for vascular diseases (VD), namely, atherosclerosis, abdominal aortic aneurysm, vascular calcification (VC) and pulmonary arterial hypertension (PAH).
A. Raucci +5 more
semanticscholar +1 more source
Longevity Factor FOXO3: A Key Regulator in Aging-Related Vascular Diseases
Frontiers in Cardiovascular Medicine, 2021 Forkhead box O3 (FOXO3) has been proposed as a homeostasis regulator, capable of integrating multiple upstream signaling pathways that are sensitive to environmental changes and counteracting their adverse effects due to external changes, such as ...
Yan Zhao, Youshuo Liu
semanticscholar +1 more source
Journal of Vascular Surgery Cases and Innovative Techniques, 2022 A 68-year-old man developed aneurysmal degeneration of the aortic arch and proximal descending aorta after an open ascending graft for a type A aortic dissection. A three-branched endovascular aortic arch repair was performed with patency of all branches
Martijn L. Dijkstra, MD, PhD +4 more
doaj +1 more source