Results 1 to 10 of about 10,815,340 (358)

Diabetic vascular diseases: molecular mechanisms and therapeutic strategies

open access: yesSignal Transduction and Targeted Therapy, 2023
Vascular complications of diabetes pose a severe threat to human health. Prevention and treatment protocols based on a single vascular complication are no longer suitable for the long-term management of patients with diabetes.
Yiwen Li   +7 more
semanticscholar   +1 more source

Endothelial senescence in vascular diseases: current understanding and future opportunities in senotherapeutics

open access: yesExperimental and Molecular Medicine, 2023
Senescence compromises the essential role that the endothelium plays in maintaining vascular homeostasis, so promoting endothelial dysfunction and the development of age-related vascular diseases.
Yeaeun Han, Sung Young Kim
semanticscholar   +1 more source

Engineering Organ-on-a-Chip Systems for Vascular Diseases.

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2023
Vascular diseases, such as atherosclerosis and thrombosis, are major causes of morbidity and mortality worldwide. Traditional in vitro models for studying vascular diseases have limitations, as they do not fully recapitulate the complexity of the in vivo
A. Shakeri   +6 more
semanticscholar   +1 more source

Folate and retinal vascular diseases

open access: yesBMC Ophthalmology, 2023
Folate, a pteroylglutamic acid derivative, participates in fundamental cellular metabolism. Homocysteine, an amino acid, serves as an intermediate of the methionine cycle and can be converted back to methionine.
Jinyue Gu, C. Lei, Meixia Zhang
semanticscholar   +1 more source

Angiopoietin/Tie2 signalling and its role in retinal and choroidal vascular diseases: a review of preclinical data

open access: yesEye, 2021
The angopoietin/tyrosine kinase with immunoglobulin and epidermal growth factor homology domains (Ang/Tie) pathway is an emerging key regulator in vascular development and maintenance.
A. Joussen   +5 more
semanticscholar   +1 more source

Berberine: A Review of its Pharmacokinetics Properties and Therapeutic Potentials in Diverse Vascular Diseases

open access: yesFrontiers in Pharmacology, 2021
Traditional Chinese medicine plays a significant role in the treatment of various diseases and has attracted increasing attention for clinical applications.
Xiaopeng Ai   +8 more
semanticscholar   +1 more source

MicroRNA-34a: the bad guy in age-related vascular diseases

open access: yesCellular and Molecular Life Sciences, 2021
The age-related vasculature alteration is the prominent risk factor for vascular diseases (VD), namely, atherosclerosis, abdominal aortic aneurysm, vascular calcification (VC) and pulmonary arterial hypertension (PAH).
A. Raucci   +5 more
semanticscholar   +1 more source

Ferroptosis of Endothelial Cells in Vascular Diseases

open access: yesNutrients, 2022
Endothelial cells (ECs) line the inner surface of blood vessels and play a substantial role in vascular biology. Endothelial dysfunction (ED) is strongly correlated with the initiation and progression of many vascular diseases. Regulated cell death, such
Hanxu Zhang   +8 more
semanticscholar   +1 more source

Crushing of a bridging stent during follow-up of endovascular branched aortic arch repair: A novel mode of failure

open access: yesJournal of Vascular Surgery Cases and Innovative Techniques, 2022
A 68-year-old man developed aneurysmal degeneration of the aortic arch and proximal descending aorta after an open ascending graft for a type A aortic dissection. A three-branched endovascular aortic arch repair was performed with patency of all branches
Martijn L. Dijkstra, MD, PhD   +4 more
doaj   +1 more source

Longevity Factor FOXO3: A Key Regulator in Aging-Related Vascular Diseases

open access: yesFrontiers in Cardiovascular Medicine, 2021
Forkhead box O3 (FOXO3) has been proposed as a homeostasis regulator, capable of integrating multiple upstream signaling pathways that are sensitive to environmental changes and counteracting their adverse effects due to external changes, such as ...
Yan Zhao, Youshuo Liu
semanticscholar   +1 more source

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