Results 141 to 150 of about 10,815,340 (358)
Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi +13 morewiley +1 more sourceEffects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial [PDF]
, 2019 Background
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy.Abano, Nenette, Abbdul-saheb, Mudhar, Adedoyin, Temi, Adell, Victoria, Adesina, Tolu, Adie, Katja, Adil-Smith, Jennifer, Ahmad, Nasar, Ahmed, Ashraf, Ahmed, Iman, Al-Mayhani, Talal, Al-Shahi Salman, Rustam, Al-Shahi Salman, Rustam, Alam, Mohammad Irfan, Albazzaz, Mo, Ali, Ali, Alipio, Francis, Allen, Christopher, Allison, Joanna, Amey, Isobel, Amis, Elaine, Amlani, Sageet, Amoils, Shannon, Amor, Kelly, Anderson, Rosemary, Andole, Sreeman, Anjum, Talat, Ankolekar, Sandeep, Annamalai, Arunkumar, Anthony, Alpha, Anversha, Ajmal, Anwar, Ijaz, Anwar, Sajjad, Appleton, Jason, Argandona, Lucia, Armitage, Jane, Ashton, Amy, Atkinson, Natalie, Auld, Grace, Avis, Joanne, Aweid, Basaam, Ayres, Georgina, Azhar, Khalid, Bagnall, Caroline, Baig, Farrukh, Baigent, Colin, Bailey, Duncan, Baird, Yolanda, Bakawala, Rehana, Baker, John, Baker, Pauline, Balazikova, Olga, Balian, Linda, Baliga, Vidya, Balitska, Olesia, Ball, Julie, Ball, Margaret, Ballantine, Robert, Bamford, John, Banaras, Azra, Barber, Mark, Barbon, Emma, Barker, James, Barr, Charlotte, Barrie, Elizabeth, Barron, Luke, Barry, Adrian, Bateman, Gavin, Bates, Michelle, Bathula, Rajaram, Battersby-Wood, Emma, Bayliss, Pauline, Beadle, Hannah, Bearne, Helen, Beaty, Teresa, Beaves, Emily, Bell, Angela, Bell, Jo, Bell, Murdina, Bellfield, Ruth, Beranova, Eva, Bergin, Adrian, Bhakri, Harbens, Bhalla, Ajay, Bharaj, Kiranjit, Bhargava, Maneesh, Bhaskaran, Biju, Bhatnagar, Priya, Bhatnagar, Priya, Birchall, Kathryn, Birns, Jonathan, Black, Toby, Blades, Alex, Blair, Caroline, Blair, Caroline, Blair, Gordon, Blane, Sujata, Blank, Catrin, Blight, Adrian, Board, Joanne, Board, Sarah, Bokhari, Maria, Bond, Kirsty, Bowring, Angela, Boxall, Cherish, Breeds, Joanna, Brew, Helen, Brezitski, Maria, Bridger, Hayley, Brodie, Fiona, Brotherton, Lucy, Broughton, David, Brown, Claire, Brown, Ellen, Brown, Pauline, Brown, Sarah, Bruce, David, Buchanan, David, Buck, Amanda, Buckle, Steve, Buckle, Steve, Buckley, Clare, Bunea, George, Burger, Ilse, Burgess, Laura, Burgess, Seona, Burssens, Evelyne, Butler, Adrian, Butler, Donna, Butler, Rebecca, Butterworth-Cowin, Nicola, Button, Denise, Buxton, Jean, Byrne, Anthony, Cageao, Julie, Caine, Sarah, Campbell, Robert, Carpenter, Michael, Carpio, Racquel, Carrie, Johanna, Cassidy, Tim, Causley, Chelsea, Chadbourn, Indra, Chadha, Dinesh, Chamberlain, Angela, Chan, kelly, Chandrakumar, Aberami, Chapman, Kath, Chapman, Nicola, Charles, Bethan, Chatterjee, Kausic, Chaudhry, Afnan, Chauhan, Meena, Chenna, Srikanth, Cherian, Suja, Cheripelli, Bharath Kumar, Chopra, Neha, Choulerton, James, Choy, Lillian, Clarke, Brian, Clarke, Caroline, Clarke, Judith, Clarke, Natasha, Clarke, Rebecca, Clarke, Samantha, Clarkson, Emma, Clay, Caroline, Clayton, Susan, Clayton-Evans, Lisa, Cluckie, Gillian, Cochrane, Helen, Codd, Laura, Cohen, David, Collins, Kayleigh, Connor, Lynda, Constantin, Carmen, Cook, Angela, Cooper, Martin, Copeland, Claire, Cosier, Tracey, Courtauld, Gillian, Couser, Mandy, Coward, Lucy, Cowie, Linda, Cox, Chantel, Cox, Chloe, Cox, Penelope, Crabtree, Karen, Crawford, Pam, Crawford, Susan, Creeden, Robyn, Crisp, Sarah, Cronin, Julie, Crook, Luci, Crosbie, Caroline, Crouch, Nichola, Crown, Rachel, Crowther, Hannah, Cuddy, Sarah, Cuenoud, Larissa, Cullen, Claire, Culmsee, Charlotte, Cunningham, James, Cunningham, Mishell, Cvoro, Vera, Dacey, Lynne, Dakin, Katy, Dallol, Bander, Dangri, Puneet, Datta, Prabal, Davey, Richard, David, Anette, David, Owen, Davies, Caroline, Davies, Ruth, Davies, Silvie, Davis, Fiona, Davis, Michelle, Day, Nicola, Dayal, Nilofer, De Berker, Henry, Deary, Ann, Denic, Hayley, Dennis, Martin, Dennis, Martin S, Denniss, Carol, Devine, Joseph, Devitt, Nicola, Dewar, Richard, Dhakal, Mahesh, Dhar, Saikat, Dickinson, Christina, Dickson, Christine, Dima, Sofia, Dinsmore, Lynn, Dixon, Lynn, Dobson, Tracey, Dodd, Angela, Dodd, Emily, Doherty, Mandy, Doherty, Mandy, Donaldson, Denise, Donnelly, Richard, Doubal, Fergus, Dow, Lindsey, Downham, Susan, Doyle, Clare, Doyle, Donna, Drever, Jonathan, du Plessis, Johann C, du Plessis, Johannes, Dube, Judith, Duberley, Stephen, Dunn, Linda, Dunne, Karen, Durairaj, Ramesh, Durman, Helen, Dutta, Dipankar, Dynan, Kevin, Edwards, Mandy, Egerton, Shuna, Eglinton, Charlotte, Eglinton, Charlotte, El Tawil, Salwa, Elfandi, Khaled, Elliot, Jennifer, Elliott, Emma, Ellis, Sam, Emberson, Jonathan, Emsley, Hedley, England, Timothy, Epstein, Daniel, Erande, Renuka, Erumere, Esther, Esisi, Bernard, Esisi, Bernard, Esson, Derek, Esson, Derek, Evans, Rachel, Evans, Sue, Eveson, David, Ewing, Jordan, Fathima, Razik, Fawcett, Michelle, Feerick, Shez, Fennelly, Ruth, Ferdinand, Phillip, Findlay, Paul, Finlay, Sarah, Finney, Kay, Fitzell, Pauline, Fitzsimmons, Paul, Fletcher, Glyn, Fletcher, Jo, Fong, Rosanna, Foot, Jayne, Foote, Leanne, Ford, Gary, Foster, Eliza, Fotherby, Ken, Fox, Charlotte, Francia, Nina, Francis, Jobbin, Fraser, Ruth, Fraser, Ruth, Fuller, Tracy, Fulton, Ailsa, Furnace, Jacqueline, Gadapa, Naveen, Gainard, Glyn, Gainsborough, Nicola, Gallagher, Jill, Gallagher, Louise, Gallifent, Rachel, Gamble, Ed, Garcia, Tatiana, Gardener, Léjeune, Garfield-Smith, Joanne, Garside, Mark, Gartrell, Imogen, Gascoyne, Rachel, Gattringer, Thomas, Gautam, Nikki, Gaylard, Jane, Gbadamoshi, Lukuman, Geraghty, Olivia, Ghaly, George, Ghatala, Rita, Ghosh, Sandip, Giallombardo, Elio, Gilham, Ellie, Gilmour, Danielle, Gilzeane, Nicola, Glass, Jon, Gleave, Laura, Glover, Rachel, Godfrey, Margi, Goff, Anita, Goorah, Neetish, Gott, Valerie, Gow, Heather, Graham, Carol, Graham, Ruth, Gray, Jane, Green, Carole, Greenwood, Richard, Gregory, Bindu, Greig, Jill, Grimwood, Gemma, Grocott, Jeanette, Grue, Rebecca, Gulliver, Diane, Guo, Fenglin, Gupwell, Karin, Guthrie, Lucy Belle, Guy, Helen, Guyler, Paul, Hague, Adam, Haider, Syed, Hairsine, Brigid, Hakim, Eluzai, Hall, Andrea, Halse, Omid, Handley, Dominic, Hann, Gail, Hannon, Niamh, Hansen, Christian, Haque, Mohammad, Hardwick, Anne, Harkness, Kirsty, Harrington, Frances, Harrington-Davies, Yasmin, Harrison, Louise, Harrison, Melanie, Harrison, Thomas, Harston, George, Harvey, Kirsten, Harvey, Miriam, Hassan, Ahamad, Hassan, Hardi, Havard, Diane, Hayes, Anne, Hayhoe, Helen, Hayman, Rachel, Hays, Carole, Hazel, Beth, Hedstrom, Amanda, Hedstrom, Amanda, Hemsley, Anthony, Henry, Margo, Herman, Jane, Hervey, Simon, Hewitt, Jonathan, Hiden, Joanne, Hogan, Caroline, Hogg, Valerie, Holden, Melinda, Holmes, Clare, Homan, Jane, Hooley, Michaela, Horan, Kathleen, Horton, Sarah, Hostettler, Isabel, Hove, Dionne, Howaniec, Laura, Howard, Gabriella, Howard, Joanne, Howard, Peter, Howcroft, Deborah, Howe, Jo, Huang, Xuya, Huggett, Isabel, Hughes, Chloe, Hughes, Claire, Hughes, Tom, Humphreys, Louise, Humphries, Fiona, Hunt, Benjamin, Hunt, Nicholas, Hunter, Annemarie, Hunter, Neil, Hurford, Frances, Hurley, Jennifer, Hussain, Malik, Hutchison, Aidan, Hyams, Benjamin, Hyatt, Lisa, Imam, Javed, Ingham, Andrea, Ingram, Tanya, Innes, Karen, Iqbal, Arshi, Iqbal, Mohammad Shazad, Irvine, Janice, Ispoglou, Sissy, Ivatts, Simone, Jackson, Benjamin, Jackson, Linda, Jagger, Jenny, Jagpal, Baljit, James, Ali, James, Claire, James, Martin, Jarapa, Rowilson, Jarrett, David, Jeffs, Carol, Jelley, Benjamin, Jenkins, Colin, Jennings-Preece, Karla, Jeyaraj, Naomi, Jha, Ratneshwari, Jinks, Emma, Johnes, Mary, Johnson, Sharon, Jones, Ifan, Jones, Ifan, Jones, Kirsty, Jones, Rachael, Jones, Stephanie, Jones, Terry, Jones, Val, Jordan, Carla, Jose, Deepa, Jose, Josin, Joshi, Yogish, Joshi, Yogish, Joyson, Anu, Jupp, Becky, Justin, Frances, Kakar, Puneet, Kalathil, Latheef, Kalladka, Dheeraj, Kamara, Christine, Kambafwile, Mary, Kane, Ingrid, Kar, Arindam, Keegan, Breffni, Keeling, Elizabeth, Keenan, Samantha, Kelavkar, Shyam, Kelly, Christine, Kelly, Debs, Kelly, Jim, Kelly, Siobhan, Keltos, Marketa, Kennedy, James, Kennedy, Kate, Kenton, Antony, Kerin, Lourda, Kerr, Enda, Kerr, Gillian, Keshvara, Rekha, Khan, Mohammad, Khan, Shagufta, Khan, Usman, Khan, Uzma, Kibutu, Faith, King, Sam, Kingwell, Hayley, Kini, Manohar, Klaasen, Katrina, Knops, Kerstin, Krishnamoorthy, Shrivakumar, Krishnamurthy, Ramesh, Krishnamurthy, Vinodh, Krishnan, Kailash, Krishnan, Manju, Krommyda, Magdalini, Kullane, Sagal, Kumar, Balakrishna, Kumar, Pradeep, Kunhunny, Swapna, Lam, Man Yee, Lambert, Caroline, Landers, Geraldine, Langhorne, Peter, Lasserson, Daniel, Latter, Laura, Law, Zhe, Lawrence, Tara, Lawson, Heidi, Leason, Sandra, Lee, Stephanie, Leggett, Jacqui, Lenti, Giulia, Lerpiniere, Christine, Lerpiniere, Christine, Licenik, Radim, Lindert, Ralf, Little, Victoria, Littleton, Edward, Ljubez, Anja, Loganathan, Thayalini, Longland, Barbara, Lopez, Paula, Lovelock, Caroline, Lowe, Gordon, Lucas, Linda, Lucas, Suzanne, Luder, Robert, Lyjko, Sue, Maanoosi, Mehran, Maatouk, Ahmad, Macaden, Ashish, MacInnes, Brian, MacLennan, Beverly, Macleod, Malcolm, MacLeod, Mary, MacLiver, Linda, MacRaild, Allan, Maddula, Mohana, Madigan, Barbara, Maguire, Holly, Maguire, Stuart, Maiden, Susan, Majis, Arshad, Majmudar, Nikhil, Makawa, Linetty, Mangion, David, Manning, Lisa, Manoj, Aravind, Mardania, Rina, Marigold, James Richard, Markova, Skarlet, Marks, Katherine, Marsden, Tracy, Marshall, Sally, Martin, Irene, Mashate, Sheila, Mason, Cathy, Mate, Abhijit, Mathieson, Philip, Matias, Oliver, Matthews, Christopher, Maund, Bev, McAlpine, Christine, McArdle, Damian, Mcauley, Sean, McCann, Stephanie, McCarron, Mark, McClelland, Beverley, McCormick, Katrina, McCormick, Katrina, McDonald, Shanni, McDonald, Susan, Mcgee, Joanne, McGhee, Caroline, McGill, Connor, McGrath, Aileen, McIlmoyle, James, McKee, Jacqueline, McLoughlin, Alison, McVerry, Ferghal, Mead, Denise, Mead, Gillian, Meir, Julie, Menon, Nisha, Mercer, Lily, Metcalf, Kneale, Miller, Keniesha, Miller, Richard, Milligan, Josette, Minks, David, Minks, David P., Miriam, Skelton, Mistri, Amit, Mitchell, Jennifer, Mitra, Dipayan, Mitra, Dipayan, Mohammed, Niaz, Mohd Nor, Azlisham, Mokoena, Betty, Moores, Andrew, Moqsith, Mohammed, Morell, Jordi, Moreton, Fiona, Morgan, Debbie, Moroney, Helen, Morse, Bethan, Moseley, Sally, Motherwell, Nichola, Moynihan, Barry, Mpelembue, Mushiya, Mudd, Paul, Muddegowda, Girish, Muir, Keith, Mukherjee, Indranil, Murali, Elodie, Murphy, Peter, Murray, Gordon D, Musarrat, Kashif, Myint, Min, Naeem, Muhammad, Naing, Zin, Nair, Anand, Nallasivan, Arumugam, Nasar, Mohammad, Nasim, Ashraf, Naylor, Charde, Needle, Ann, Nelson, Sandra, Newby, David E, Newton, Sophie, Ng, Kheng Xiong, Ngo, David, Nguyen, Vinh, Ngwako, Mmua, Ni, Hlaing, Nicholas, Paul, Nicolson, Anne, Niranchanan, Rangah, Nisar, Nabeela, Njoku, Kelechi, Nott, Claire, Nott, Claire, Nozedar, Tarn, Nyabadza, Sheila, O'Brien, Eoin, O'Brien, Richard, O'Brien, Richard, O'Connell, Susan, O'Loughlin, Victoria, O'Reilly, Joanna, O'Toole, Sarah, OConnell, Janice, Oji, Nnebuife, Orath Prabakaran, Rajalakshmi, Orefo, Chukwuka, Orugun, Enoch, Osborn, Mairead, Osborne, Emily, Oshodi, Anne, Osman, Ahmed, Ovington, Catherine, Owings, Paula, Owoyele, Emmanuelle, Owusu-Agyei, Peter, Pai, Yogish, Palmer, Jeb, Papavasileiou, Vasileios, Parakramawansha, Ruwan, Parker, Richard, Parry, Anthea, Parry-Jones, Adrian, Pasco, Kath, Patel, Bhavini, Patel, Champa, Patel, Farzana, Patel, Krishna, Patterson, Chris, Paulton, Ruth, Pawley, Corinne, Peixoto, Cassilda, Penge, Justin, Perez, Jane, Perfitt, Rebekah, Perkins, Charlotte, Perry, David, Perry, Jack, Persad, Nicola, Peters, Jenny, Pettitt, Kerry, Phiri, Duke, Pitt-Ford, Alexandra, Pitt-Kerby, Tressy, Plewa, Catherine, Poku, Philip, Ponnambath, Suheil, Poultney, Una, Pound, Susan, Power, Michael, Pressly, Vanessa, Price, Fiona, Proeschel, Harald, Punekar, Shuja, Punter, Martin, Pusalkar, Aparna, Putterill, Janet, Quinn, Leanne, Quinn, Outi, Qureshi, Sammie, Ragab, Suzanne, Raghunathan, Senthil, Rahman, Bithi, Rai, Baljinder, Raj, Sonia, Rajapakse, Anoja, Rajkumar, Chakravarthi, Ramachandran, Sankaranarayana, Ramadan, Hawraman, Ramshaw, Alex, Rana, Pratap, Randall, Marc, Rashed, Khalid, Rashmi, Sindhu, Ravenhill, Garth, Rayessa, Rayessa, Reckless, Ian, Reddan, Julie, Reddan, Julie, Redgrave, Jessica, Redjep, Ozlem, Remegoso, Alda, Richard, Bella, Richards, Emma, Rinkel, Gabriel, Roberts, Josh, Robinson, Matthew, Robinson, Naomi, Rodgers, Alicia, Rodrigues, Mark A, Rodriguez, Aryelly, Roffe, Christine, Roffe, Jack, Roganova, Tatjana, Rogers, Emily, Rogers, Gill, Rojas, Javier, Ross, Sarah, Roughan, Caroline, Rudd, Tony, Rudenko, Hannah, Saada, Janak, Saastamoinen, Kari, Sajid, Mahmud, Sakka, Eleni, Salehin, Maqsud, Salek-Haddadi, Afraim, Salih, Isam, Sally, Moore, Sandercock, Peter A G, Sangombe, Mirriam, Sangster, Graeme, Sanyal, Ranjan, Sarah, Procter, Sarah, Procter, Sattar, Naweed, Sattar, Saira, Saulat, Afaq, Saulat, Afaq, Schofield, Christine, Schulz, Ursula, Schumacher, Natasha, Schwarz, Stefan, Seagrave, Samantha, Sekaran, Lakshmanan, Sesay, Juliana, Sethuraman, Sakthivel, Shackcloth, Daniela, Shah, Alex, Shah, Sweni, Shahmehri, Shahrzad, Sharma, Nikhil, Sharpe, Simon, Shaw, Kelly Marie, Shaw, Louise, Sheikh, Saima, Shekhar, Raj, Shelton, Faye, Shinh, Naval, Shread, Ian, Shukla, Avani, Siddegowda, Prasad, Siddiq, Muhammad, Siddiqui, Amber, Siddiqui, Anwer, Sigsworth, Andrew, Simon, Rohan, Sims, Don, Singh, Arun, Sinha, Devesh, Skinner, Helen, Slade, Peter, Smart, Amanda, Smith, Andrew, Smith, Fiona, Smith, Gemma Marie, Smith, Simon, Smith, Wilma, Smyth, Nigel, Spencer, Jayne, Sprigg, Nikola, Sprigg, Nikola, Srinivasan, Meena, Stafford, Samantha, Stafford, Samantha, Stanners, Andrew, Steele, Amy, Stephen, Jacqueline, Stephens, Claire, Stevens, Angela, Stevens, Stephanie, Stevenson, Sarah, Stewart, Kelvin, Stocks, Kathy, Stone, Andrew, Storton, Sharon, Strain, David, Subramonian, Santhosh, Sudlow, Cathie, Sudlow, Cathie L M, Sukdeo, Varthi, Sullivan, Frank, Sultan, Sulaiman, Suttling, Anne, Sutton, Claire, Sutton, Patrick, Sutton, Victoria, Sword, Jane, Sykes, Lucy, Symonds, Stuart, Szabo, Susan, Tallantyre, Emma, Tanate, Alfonso, Tandy, Jane, Tate, Margaret, Tauro, Suzanne, Tayler, Michelle, Taylor, Pat, Taylor, Vicky, Teal, Rachel, Temple, Natalie, Thant, Hlaing, Thavanesan, Kamy, Thomas, Isobel, Thomas, Kelly, Thomas, Philip, Thomas, Sarah, Thompson, Philip, Thompson, Susan, Thompson, Teresa, Thompson-Jones, Helen, Thomson, Audrey, Thornthwaite, Sarah, Thorpe, Kevin, Tilley, Victoria, Tiwari, Divya, Tomlin, Dawn, Tomlinson, Benjamin, Treadwell, Shelley, Tribbeck, Michele, Trippier, Sarah, Triscott, Claire, Triscott, Claire, Tryambake, Dinesh, Tucker, Laura, Tucker, Susan, Turfrey, Jennifer, Tysoe, Sharon, Ullah, Khalil, Valentine, Stacey, van Someren, Chloe, Varquez, Resti, Vasileiadis, Evangelos, Vassallo, Joseph, Venter, Marius, Veraque, Emelda, Verrion, Anna, Vettimootal Johnson, Venetia, Vickers, Carinna, Walford, Jamie, Walker, Allan, Walker, Marion, Walker, Pauli, Walker, Susannah, Wallace, Aine, Wallace, Rebecca, Wallace, Rebecca, Walstow, Deborah, Walter, Deborah, Walters, Ashleigh, Wani, Mushtaq, Ward, Deborah, Wardlaw, Joanna M, Watchurst, Caroline, Waterfield, Kelly, Waterfield, Kelly, Watson, Fran, Waugh, Dean, Webb, Tom, Webber, Adam, Webster, Timothy, Weinling, Marie, Weir, Nic, Weir, Pauline, Welch, Angela, Werring, David, Werring, David J, Whitcher, Alison, White, James, White, Julie, White, Philip M, White, Susan, Whiteley, William, Whiteley, William N, Whiteman, Jessica, Whiteman, Jessica, Whiting, Robert, Whittamore, Katherine, Wiggam, Ivan, Wilding, Peter, Wilkes, Gwendoline, Wilkinson, Mark, Willberry, Angela, Williams, Carol, Williams, Rebecca, Williams-Yesson, Barbara, Willmot, Mark, Wilson, David, Wilson, Duncan, Wilson, Jenny, Wilson, Lisa, Wilson, Sarah, Wiltshire, Alison, Wood, Diane, Wood, Edith, Wood, Lisa, Woodward, Stephen, Wright, Fiona, Wroath, Belinda, Wynter, Inez, Yadava, Rajendra, Yip, Brigitte, Young, Andrew, Zachariah, George, Zahoor, Tajammal, Zoe, Mellor +966 morecore +5 more sourcesVascular Teams in Peripheral Vascular Disease
Journal of the American College of Cardiology, 2019 Peripheral vascular disease affects millions of individuals worldwide, and results in significant morbidity and mortality. The complex nature of the disease, the presence of multiple comorbidities, and the existence of a wide variety of therapeutic options suggests that a multidisciplinary approach to treatment has the potential to improve care of ...Dhaval, Kolte, Sahil A, Parikh, Gregory, Piazza, Mehdi H, Shishehbor, Joshua A, Beckman, Christopher J, White, Michael R, Jaff, Alexander, Iribarne, Tom C, Nguyen, James B, Froehlich, Kenneth, Rosenfield, Herbert D, Aronow +11 moreopenaire +2 more sourcesCalcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter
FEBS Open Bio, EarlyView.Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata +7 morewiley +1 more sourceElevated serum levels of macrophage migration inhibitory factor and stem cell growth factor β in patients with idiopathic and systemic sclerosis associated pulmonary arterial hypertension. [PDF]
, 2015 Pulmonary arterial hypertension (PAH) can be idiopathic or secondary to autoimmune diseases, and it represents one of the most threatening complications of systemic sclerosis (SSc).Alessandri, Cristiano, Badagliacca, Roberto, Pendolino, Monica, Poscia, Roberto, Riccieri, Valeria, Sciarra, Iliana, Stefanantoni, Katia, Valesini, Guido, Vasile, M, Vizza, Carmine Dario +9 morecore +2 more sourcesDDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan +7 morewiley +1 more source
