Results 81 to 90 of about 10,815,340 (358)

Empagliflozin on top of metformin treatment improves arterial function in patients with type 1 diabetes mellitus

Cardiovascular Diabetology, 2018
Background Deteriorated arterial function and high incidence of cardiovascular events characterise diabetes mellitus. Metformin and recent antidiabetic drugs, SGLT2 inhibitors, reduce cardiovascular events.
Mojca Lunder, Miodrag Janić, Miha Japelj, Andrej Juretič, Andrej Janež, Mišo Šabovič   +5 more
doaj   +1 more source

Effectiveness and safety of anticoagulant versus antiplatelet therapy in patients after endovascular revascularisation of the lower limb

Zdravniški Vestnik, 2022
Background: After revascularisation, patients with peripheral arterial disease (PAD) are routinely prescribed antiplatelet treatment (APT). Patients who receive anticoagulant treatment (ACT) due to comorbidity are an exception.
Kevin Pelicon, Klemen Petek, Anja Boc, Vinko Boc, Nataša Kejžar, Tjaša Vižintin Cuderman, Aleš Blinc   +6 more
doaj   +1 more source

MicroRNA‐125b in vascular diseases: An updated systematic review of pathogenetic implications and clinical applications

Journal of Cellular and Molecular Medicine, 2019
Epigenetic changes, particularly non‐coding RNAs, have been implicated extensively in the pathogenesis of vascular diseases. Specific miRNAs are involved in the differentiation, phenotypic switch, proliferation, apoptosis, cytokine production and matrix ...
C. Chao, Hsiang-Yuan Yeh, T. Yuan, C. Chiang, Huei-Wen Chen   +4 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Multimodal optical diagnostics of the microhaemodynamics in upper and lower limbs [PDF]

, 2019
The introduction of optical non-invasive diagnostic methods into clinical practice can substantially advance in the detection of early microcirculatory disorders in patients with different diseases.
Dremin, Viktor V., Dunaev, Andrey V., Goltsov, Alexey, Makovik, Irina N., Rafailov, Edik U., Sokolovski, Sergei G., Zherebtsov, Evgeny A., Zherebtsova, Angelina I.   +7 more
core   +4 more sources

Intravitreal Anti-VEGF Drugs and Signals of Dementia and Parkinson-Like Events: Analysis of the VigiBase Database of Spontaneous Reports [PDF]

, 2020
Introduction: Since vascular endothelial growth factor (VEGF) regulates several aspects of the central nervous system, particularly in dopaminergic neurons, VEGF inhibitors may be linked to Parkinson-like events and dementia, or variants of these ...
Avery, Bergvall, Caballero, Campochiaro, Cutroneo, de Jong, De Rossi, Evans, Ferrara, Ferrara, Kumar, Lim, Lindquist, McColl, Meyer, Robinson, Sanchez, Sharma, Sheikh, Simó, Steen, Storkebaum, Sultana, Thulliez, Tian, Trifirò, Ueta, Wong, Yasuhara, Ylä-Herttuala, Zachary   +30 more
core   +4 more sources

Anticoagulant management in an antithrombin-deficient pregnant woman with a history of venous thromboembolism: a case report

Thrombosis Journal
Background Antithrombin deficiency (ATD) in pregnant patients significantly increases the risk of venous thromboembolism (VTE), but guidelines for managing anticoagulation during pregnancy, labour, and postpartum in patients with ATD are limited.
Matija Kozak, Tjaša Vižintin Cuderman, Mojca Božič Mijovski, Miha Lučovnik, Marko Miklič, Gregor Tratar, Tamara Rojnik   +6 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Arteriogenesis versus angiogenesis: similarities and differences [PDF]

, 2007
Cardiovascular diseases account for more than half of total mortality before the age of 75 in industrialized countries. To develop therapies promoting the compensatory growth of blood vessels could be superior to palliative surgical surgical ...
Eitenmüller, Inka, Heil, Matthias, Schaper, Wolfgang, Schmitz-Rixen, Thomas   +3 more
core   +1 more source

Efficacy and safety of mechanical pulmonary valve replacement: a comprehensive systematic review and meta-analysis

Journal of Cardiothoracic Surgery
Background Pulmonary valve replacement (PVR) is the most common valve replacement procedure for pulmonary valve dysfunction in congenital heart diseases (CHD).
Ali Rafati, Sina Rashedi, Yeganeh Pasebani, Milad Vahedinejad, Hamed Ghoshouni, Yaser Toloueitabar, Mostafa Mousavizadeh, Sedigheh Saedi, Amirhosein Jalali, Zahra Khajali, Hassan Tatari, Fahimeh Farrokhzadeh, Hooman Bakhshandeh, Maziar Gholampour Dehaki, Behshid Ghadrdoost, Parham Sadeghipour   +15 more
doaj   +1 more source