Results 91 to 100 of about 1,251,100 (314)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Vascular disorders of the liver: recommendations from the Italian Association for the Study of the Liver (AISF) ad hoc committee. [PDF]

, 2011
This review summarizes the document elaborated by the Italian Association for the Study of the Liver (AISF) ad hoc committee "Vascular disorders of the liver" on the primary circulatory liver diseases, which include Budd-Chiari syndrome, obstruction of ...
Riggio O, Sacerdoti D, Senzolo M, Primignani M, Italian Association for the Study of the Liver AISF ad hoc committee Vascular disorders of the liver, SACERDOTI, DAVID   +5 more
core   +1 more source

MicroRNAs in Vascular Eye Diseases [PDF]

, 2020
Since the discovery of the first microRNA (miRNA) decades ago, studies of miRNA biology have expanded in many biomedical research fields, including eye research.
Jing Chen, Chi-Hsiu Liu, William R. Britton, Shuo Huang   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Impact of vascular diseases on the progression of mild cognitive impairment to Alzheimer’s disease [PDF]

, 2015
Introduction: Mild cognitive impairment does not meet the criteria for the diagnosis of dementia, but reaching this diagnosis raises concern about the future state of a patient due to the possibility of the conversion to Alzheimer’s disease.
Maria Barcikowska, Tomasz Nesteruk, Maria Styczyńska, Marta Nesteruk   +3 more
core   +1 more source

Outpatient Treatment in Low-Risk Pulmonary Embolism Patients Receiving Direct Acting Oral Anticoagulants Is Associated With Cost Savings

Clinical and Applied Thrombosis/Hemostasis, 2020
Direct oral anticoagulants (DOAC) are first line treatment for pulmonary embolism (PE). Treatment of acute PE is traditionally hospital based and associated with high costs.
Raein Ghazvinian MD, Johan Elf MD, Sofia Löfvendahl Economist, Jan Holst MD, Anders Gottsäter MD   +4 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Modern treatments of inflammatory vascular diseases [PDF]

Inflammatory vascular diseases are a significant group of conditions with high prevalence and varied symptoms affecting multiple organs, potentially leading to lifelong impairment.
Yousef, Omar Ahmed Elsayed
core  

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? [PDF]

, 2009
<p><b>Background:</b> Circulating inflammatory markers may more strongly relate to risk of fatal versus nonfatal cardiovascular disease (CVD) events, but robust prospective evidence is lacking.
Jukema, J.W., Westendorp, R.G.J., Lowe, G.D., Murray, H.M., Cobbe, S., de Craen, A.J.M., Blauw, G.J., Ford, I., Welsh, P.I., Murphy, M.B., Buckley, B.M., Macfarlane, P.W., Stott, D.J., Sattar, N.A., Shepherd, J.   +14 more
core   +1 more source