Results 81 to 90 of about 1,251,100 (314)

BMP signaling in vascular diseases [PDF]

open access: yes, 2012
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-β (TGF-β) family that signal via type I and type II serine/threonine kinase receptors and intracellular Smad transcription factors.
Cai, J.   +11 more
core   +1 more source

Slovenian recommendations for the detection and treatment of venous thrombosis

open access: yesZdravniški Vestnik, 2016
 * no ...
Matija Kozak   +7 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Cancer Therapy by Targeting Vascular Endothelial Cell Growth Factor- and Non-Vascular Endothelial Cell Growth Factor-Mediated Angiogenesis [PDF]

open access: yes, 2010
Both genetic alterations and epigenetic factors contribute to the switch of the angiogenic phenotype in pathological tissues. Although signaling pathways of individual angiogenic factors are relatively well characterized, the complex interplay between ...
Cao, Y,, Yihai Cao
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Outcome of primary PCI – An Indian tertiary care center experience

open access: yesIndian Heart Journal, 2014
Objective: To assess the feasibility and outcomes of primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) in Indian Scenario.
Vijayakumar Subban   +11 more
doaj   +1 more source

Assessment of resting myocardial blood flow in regions of known transmural scar to confirm accuracy and precision of 3D cardiac positron emission tomography

open access: yesEJNMMI Research, 2023
Background Composite invasive and non-invasive data consistently demonstrate that resting myocardial blood flow (rMBF) in regions of known transmural myocardial scar (TMS) converge on a value of ~ 0.30 mL/min/g or lower.
Robert M. Bober   +3 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

B-flow Ultrasonography of Peripheral Vascular Diseases [PDF]

open access: yes, 2005
B-flow ultrasonography (US) is a new US technology, which has recently been utilized for the investigation of vascular diseases. In this pictorial essay, we demonstrate the B-flow US imaging presentations of various peripheral vascular diseases ...
Wang, Hsin-Kai   +4 more
core   +1 more source

FAK Family Kinases in Vascular Diseases [PDF]

open access: yes, 2020
In various vascular diseases, extracellular matrix (ECM) and integrin expression are frequently altered, leading to focal adhesion kinase (FAK) or proline-rich tyrosine kinase 2 (Pyk2) activation.
Kyuho Jeong   +2 more
core   +1 more source

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