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Vascular endothelial growth factor

Journal of Neuro-Oncology, 1997
Vascular endothelial growth factor (VEGF) is a hypoxia-inducible angiogenesis and vascular permeability factor which is expressed in high amounts in perinecrotic palisading cells in human glioblastomas. In vitro VEGF gene expression is enhanced approximately ten times by hypoxia.
Plate, Karlheinz, Warnke, Peter C.
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Intravitreal vascular endothelial growth factor

Graefe's Archive for Clinical and Experimental Ophthalmology, 2014
To evaluate whether a specific pre-analytical stabilization regimen is needed for naïve vitreous taps to detect true values of intrinsic VEGF levels.Fourteen consecutive patients with different vitreomacular pathologies without blood-retina-barrier breakdown were scheduled for standard 23-gauge three-port pars plana vitrectomy, and naïve vitreous taps ...
Thomas, Bertelmann   +6 more
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Vascular Endothelial Growth Factor

2003
The striking structural and anatomical parallels between the vasculature and the nervous system is reflected by the fact that these two organ systems appear to use related mechanisms during their development. Thus, it is not surprising that an increasing number of vascular biologists and researchers in the neuroscience field are fascinated by molecules
D GABRILOVICH, M DIKOV
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Vascular Endothelial Growth Factor and Vascular Homeostasis

Proceedings of the American Thoracic Society, 2011
Vascular endothelial growth factor (VEGF) is the angiogenic factor promoting and orchestrating most, if not all, processes of neovascularization taking place in the embryo and the adult. VEGF is also required to sustain newly formed vessels and plays additional multiple roles in the maintenance and function of certain mature vascular beds ...
Alon, Lazarus, Eli, Keshet
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Vascular endothelial growth factor

The International Journal of Biochemistry & Cell Biology, 1998
Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis in development, in cancer and in other important diseases. VEGF regulates multiple endothelial cell functions including mitogenesis, permeability, vascular tone, and the production of vasoactive molecules.
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Role of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptors in Vascular Development

1999
Distinct cellular processes mediate blood-vessel formation during embryogenesis (Beck and D’Amore 1997; Carmeliet and Collen 1998a; Folkman and D’Amore 1996; Noden 1989; Risau 1997; Wilting and Christ 1996) (Fig. 1). Initially, mesodermal cells differentiate in situ into early haemangioblasts and form cellular aggregates (blood islands), in which the ...
P, Carmeliet, D, Collen
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Multimodality imaging of vascular endothelial growth factor and vascular endothelial growth factor receptor expression

Frontiers in Bioscience, 2007
Angiogenesis is a critical process in both physiological development and many pathological processes. Vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) signaling pathway plays a pivotal role in regulating angiogenesis. Many therapeutic agents targeting VEGF and VEGFR are currently in preclinical and clinical development.
Weibo, Cai, Xiaoyuan, Chen
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Vascular Endothelial Growth Factor Causes Endothelial Proliferation After Vascular Injury

Biochemical and Biophysical Research Communications, 1995
Vascular endothelial growth factor was infused into rat carotid arteries for 3 minutes immediately after endothelial denudation by balloon injury. Endothelial proliferation was determined by immunohistochemical labelling of proliferating cell nuclear antigen using Häutchen preparations.
P A, Burke   +2 more
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Vascular Endothelial Growth Factor in Cervical Carcinoma

Obstetrics & Gynecology, 1999
To quantitate vascular endothelial growth factor of cervical carcinoma and elucidate its clinical correlation.Intratumoral protein levels of vascular endothelial growth factor were measured in 104 cervical cancer patients and in 30 cervical tissue specimens of benign gynecologic diseases as controls. The concentrations were correlated with clinical and
W F, Cheng   +5 more
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