Results 91 to 100 of about 115,507,522 (254)

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

Angiogenesis and expression of vascular endothelial growth factor and endostatin protein in myocardial infarction rat model

Bangladesh Journal of Pharmacology, 2016
The aim of this study was the effects of supplementing qi and herbs that promote neovascularization on angiogenesis and expressions of vascular endothelial growth factor and endostatin protein in experimentally induced acute myocardial infarction in rats.
Chenglong Zheng, Panchu Yang, Lu Zhang, Zhiyong Wang, Kun Chen, Yue Lan, Xing Zhai, Kun Huang, Shuwen Guo   +8 more
doaj   +1 more source

Mesoporous bioactive glass scaffolds for efficient delivery of vascular endothelial growth factor

, 2013
In this article, we, for the first time, investigated mesoporous bioactive glass scaffolds for the delivery of vascular endothelial growth factor. We have found that mesoporous bioactive glass scaffolds have significantly higher loading efficiency and ...
Wu, Chengtie, Xiao, Yin, Fan, Wei, Chang, Jiang   +3 more
core   +1 more source

Patterned ELR‐Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface Topography

Advanced Healthcare Materials, EarlyView.
Micro‐ and nano‐patterned elastin‐like recombinamer (ELR) hydrogels integrate bioactive matrix chemistry with defined surface topography. The combined cues promote rapid endothelial cell capture, alignment, and monolayer formation on soft substrates.
Jagoda Litowczenko, Yannick Richter, Martyna Michalska, Piotr Paczos, Karine Tadevosyan, Daniel Uribe, Jose Carlos Rodriguez‐Cabello, Ioannis Papakonstantinou, Angel Raya   +8 more
wiley   +1 more source

Placenta growth factor not vascular endothelial growth factor A or C can predict the early recurrence after radical resection of hepatocellular carcinoma

, 2009
The purpose of this study was to evaluate the relationship between the expression of PlGF in tumor tissue and clinical outcomes in HCC patients. Tumor PlGF and vascular endothelial growth factor (VEGF)-A and VEGF-C mRNA were analyzed.
何明志;陳炯年;李心予;謝豐舟;孫家棟;章齊倫;賴允婷;李伯皇, Ho, Ming-Chih; Chen, Chiung-Nien; Lee, Hsin-yu; Hsieh, Fon-Jou; Shun, Chia-Tung; Chang, Chi-Lun; Lai, Yeun-Tyng; Lee, Po-Huang   +1 more
core   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

Advanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira, Luisa de Roy, Anna‐Lotta Feldmeier, Mubashir Ahmad, Sofia Pilão, Maria Ahrens, Anita Ignatius, Carsten Linti, Andreas Martin Seitz   +8 more
wiley   +1 more source

Tumour cells expressing single VEGF isoforms display distinct growth, survival and migration characteristics [PDF]

, 2014
Vascular endothelial growth factor-A (VEGF) is produced by most cancer cells as multiple isoforms, which display distinct biological activities. VEGF plays an undisputed role in tumour growth, vascularisation and metastasis; nevertheless the functions of
Reyes-Aldasoro, Constantino C., Steele, A.J., Constantino C Reyes-Aldasoro, Harris Sheila, English William R., English, W. R., Kanthou, Chryso, Diane V Lefley, Reyes-Aldasoro, C.C., Sheila Harris (77307), Reyes-Aldasoro Constantino C., Lefley, D. V., Dos Santos, S. A., Andrew J Steele, English, William R., Dachs, G. U., English, W.R., Steele Andrew J., Sheila Harris, Dachs Gabi U., Greco, Olga, Gillian M. Tozer (167783), Claudia Coralli-Foxon, Kanthou Chryso, Reyes-Aldasoro, C. C., William R English, Steele, Andrew J., Tozer, G. M., Gabi U Dachs, Coralli-Foxon, Claudia, Olga Greco (614634), Harris, S., Olga Greco, Andrew J. Steele (614632), Sofia A. Dos Santos (614635), Dachs, G.U., Dos Santos, S.A., Claudia Coralli-Foxon (614633), Harris, Sheila, Sofia A Dos Santos, Coralli-Foxon Claudia, Greco Olga, Tozer Gillian M., Chryso Kanthou, Gillian M Tozer, Tozer, Gillian M., William R. English (184202), Dos Santos Sofia A., Kanthou, C., Lefley, Diane V., Dos Santos, Sofia A., Chryso Kanthou (22774), Greco, O., Gabi U. Dachs (614630), Steele, A. J., Lefley, D.V., Diane V. Lefley (614631), Dachs, Gabi U., Constantino C. Reyes-Aldasoro (324791), Lefley Diane V., Coralli-Foxon, C., Tozer, G.M.   +61 more
core   +2 more sources

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Measurement of plasma levels of vascular endothelial growth factor in prostate cancer patients: relationship with clinical stage, Gleason score, prostate volume, and serum prostate-specific antigen Medida da concentração plasmática do fator de crescimento do endotélio vascular em pacientes com câncer prostático: relação com estado clinico, gleason score, volume prostático e PSA sérico

Clinics, 2006
PURPOSE: This study focused on circulating levels of vascular endothelial growth factor in patients with prostate cancer compared to a normal population. METHODS: We analyzed 26 normal individuals and 80 patients with prostate cancer.
José Luis Ferreira Duque, Kevin R. Loughlin, Rosalyn M. Adam, Philip Kantoff, Eduardo Mazzucchi, Michael R. Freeman   +5 more
doaj   +1 more source

Angiogenesis-dependent and independent phases of intimal hyperplasia. [PDF]

, 2004
BACKGROUND: Neointimal vascular smooth muscle cell (VSMC) proliferation is a primary cause of occlusive vascular disease, including atherosclerosis, restenosis after percutaneous interventions, and bypass graft stenosis. Angiogenesis is implicated in the
De Muinck, E, Ferrara, N, Simons, M, Khurana, R, Zhuang, Z, Martin, JF, Murakami, M, Zachary, I, Bhardwaj, S, Yla-Herttuala, S   +9 more
core