Results 261 to 270 of about 706,179 (309)

Vascular Endothelial Growth Factor-C A Growth Factor for Lymphatic and Blood Vascular Endothelial Cells

Trends in Cardiovascular Medicine, 1998
The endothelial cells lining all vessels of the circulatory system have been recognized as key players in a variety of physiological and pathological settings. They act as regulators of vascular tone via the inducible nitric oxide system and in angiogenesis, the formation of blood vessels de novo. Aberrant regulation of endothelial cells contributes to
B, Enholm   +3 more
openaire   +2 more sources

Vascular Endothelial Growth Factor A in Intraocular Vascular Disease

Ophthalmology, 2013
The vascular beds supplying the retina may sustain injury as a result of underlying disease such as diabetes, and/or the interaction of genetic predisposition, environmental insults, and age. The vascular pathologic features observed in different intraocular vascular diseases can be categorized broadly as proliferation, exemplified by proliferative ...
Joan W, Miller   +3 more
openaire   +2 more sources

Co-regulatory potential of vascular endothelial growth factor–A and vascular endothelial growth factor–C in thyroid carcinoma

Human Pathology, 2013
Vascular endothelial growth factor (VEGF) promotes growth of blood or lymphatic vessels. The aim of the current study is to identify relationships between VEGF-A and VEGF-C, and their impact in angiogenesis and metastases in thyroid cancers. VEGF-A and VEGF-C mRNA and protein expression was investigated in 136 thyroid cancers (123 papillary thyroid ...
Salajegheh, Ali   +9 more
openaire   +3 more sources

Prognostic Importance of Vascular Endothelial Growth Factor-A Expression and Vascular Endothelial Growth Factor Polymorphisms in Epithelial Ovarian Cancer

International Journal of Gynecological Cancer, 2009
Vascular endothelial growth factors (VEGFs) play a central role in angiogenesis and consequently, in various steps of ovarian carcinogenesis. Gene polymorphisms within the VEGF system have revealed a correlation with prognosis in some malignancies. The aim of the present study was to examine the possible importance of 2 VEGF polymorphisms and VEGF-A ...
Smerdel, Maja   +5 more
openaire   +3 more sources

Lidocaine inhibits vascular endothelial growth factor-A-induced angiogenesis

Journal of Anesthesia, 2020
Angiogenesis is closely related to the pathophysiology of diseases such as cancer or ischemia. Here, we investigated the effect of lidocaine at clinically effective blood concentrations on vascular endothelial growth factor A (VEGF-A)-induced angiogenesis.
Shogo Suzuki   +4 more
openaire   +2 more sources

Vascular Endothelial Growth Factor (VEGF) Inhibition - A Critical Review

Anti-Cancer Agents in Medicinal Chemistry, 2007
Angiogenesis, or formation of new blood capillaries from preexisting vessels, plays both beneficial and damaging roles in the organism. It is a result of a complex balance of positive and negative regulators, and vascular endothelial growth factor (VEGF) is one of the most important pro-angiogenic factors involved in tumor angiogenesis.
Irina Sousa, Moreira   +2 more
openaire   +2 more sources

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

Science, 1989
Vascular endothelial growth factor (VEGF) was purified from media conditioned by bovine pituitary folliculostellate cells (FC). VEGF is a heparin-binding growth factor specific for vascular endothelial cells that is able to induce angiogenesis in vivo. Complementary DNA clones for bovine and human VEGF were isolated from cDNA libraries prepared from FC
D W, Leung   +4 more
openaire   +2 more sources

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