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Current Vascular Pharmacology, 2017
Angiogenesis is defined as the physiological process by which new blood vessels develop from pre-existing vessels; either by sprouting or intussusception.
K. Siveen+8 more
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Angiogenesis is defined as the physiological process by which new blood vessels develop from pre-existing vessels; either by sprouting or intussusception.
K. Siveen+8 more
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Biology and therapeutic targeting of vascular endothelial growth factor A
Nature reviews. Molecular cell biology, 2023Lorena Pérez-Gutiérrez, N. Ferrara
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Vascular endothelial growth factors in cardiovascular medicine
Journal of Cardiovascular Medicine, 2008The discovery of vascular endothelial growth factors (VEGFs) and their receptors has considerably improved the understanding of the development and function of endothelial cells. Each member of the VEGF family appears to have a specific function: VEGF-A induces angiogenesis (i.e.
Ugo Testa+2 more
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Vascular endothelial growth factor in reproductive biology
Current Opinion in Obstetrics and Gynaecology, 1999The critical role of angiogenesis in embryology and tumor biology has been recognized for more than 20 years. However, the fact that neovascularization is essential to processes in mammalian female reproduction has only recently been appreciated widely. In this review we focus on a single angiogenic growth factor, vascular endothelial growth factor. As
Dan I. Lebovic+2 more
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Inhibitors of Vascular Endothelial Growth Factor in Cancer
Cardiovascular & Hematological Agents in Medicinal Chemistry, 2008Angiogenesis is a complex process that is regulated by pro- and antiangiogenic factors. These factors can emanate from diverse sources including cancer cells, stromal cells, blood and extracellular matrix. Their relative contribution is likely to change with tumor type and tumor site.
Mohammad H. Pourgholami, David L. Morris
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RPE and the Vascular Endothelial Growth Factor [PDF]
Vascular endothelial growth factor (VEGF) is a major pro-angiogenic cytokine, but also exerts many additional physiological functions in the retina. The retinal pigment epithelium (RPE) is a major source for VEGF in the retina, especially affecting the endothelium of choriocapillaris but also photoreceptors and the RPE itself. VEGF is regulated on many
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Vascular-endothelial-growth-factor-A-inhibitors
Reactions weekly, 2023Jan
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Vascular endothelial growth factors and angiogenesis.
Annales d'endocrinologie, 2000VEGF was discovered in 1989. Research -conducted over the past 10 years has -demonstrated that VEGF is a major regulator of angiogenesis and vasculogenesis. This paper reviews the molecular data on the multiple forms of VEGF, their signalling and accessory receptors. Five genes encoding VEGF-like proteins have been identified; the different isoforms of
Frelin, C., Ladoux, A., d'Angelo, Gisela
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Vascular endothelial growth factor and POEMS
Neurology, 2006In this issue, Kuwabara et al.1 report on the use of high-dose melphalan and autologous peripheral blood stem cell transplantation (auto-PBSCT, four patients) and high-dose melphalan only (eight patients) in treatment of POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes) syndrome, typical features of which are illustrated ...
Ja Nean K. Engelstad+2 more
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Vascular endothelial growth factor: a neurovascular target in neurological diseases
Nature Reviews Neurology, 2016Christian Lange+4 more
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