Results 141 to 150 of about 982,599 (398)

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Expression of angiogenic factors in neurofibromas [PDF]

open access: yes, 2003
: We studied the expression of angiogenic factors (vascular endothelial growth factor, basic fibroblast growth factor, platelet-derived growth factor and hepatocyte growth factor) in cutaneous neurofibroma samples from patients with neurofibromatosis-1 ...
Ichikawa Eiko   +5 more
core   +2 more sources

Hypercholesterolemia-induced increase in plasma oxidized LDL abrogated pro angiogenic response in kidney grafts

open access: yesJournal of Translational Medicine, 2019
Background Renal transplantation is increasingly associated with the presence of comorbidity factors such as dyslipidemia which could influence the graft outcome.
Thomas Kerforne   +9 more
doaj   +1 more source

A Spatial Model of Tumor-Host Interaction: Application of Chemotherapy [PDF]

open access: yesMath. Biosci. Eng. 6(3):521-545, 2009, 2008
In this paper we consider chemotherapy in a spatial model of tumor growth. The model, which is of reaction-diffusion type, takes into account the complex interactions between the tumor and surrounding stromal cells by including densities of endothelial cells and the extra-cellular matrix.
arxiv  

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor.

open access: yesCancer Research, 2006
Malignant gliomas are highly lethal cancers dependent on angiogenesis. Critical tumor subpopulations within gliomas share characteristics with neural stem cells.
S. Bao   +9 more
semanticscholar   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Factors of angiogenesis in the development of physiological and pathological processes of the female gonads

open access: yesБюллетень сибирской медицины, 2016
The literature review focuses on the role of various growth factors in the developing vasculature of the ovary. Vascularization plays an important role in physiological processes such as development and atresia of a follicle, the formation of the yellow ...
V. G. Zenkina
doaj   +1 more source

Mechanisms of vascular damage in SSc—implications for vascular treatment strategies [PDF]

open access: yes, 2017
Vascular abnormalities are a major component of SSc, but little is known about the events or mechanisms that initiate vascular injury and prevent its repair.
Distler, J. H. W.   +3 more
core  

Gremlin is a novel agonist of the major pro-angiogenic receptor VEGFR2 [PDF]

open access: yes, 2010
The bone morphogenic protein antagonist gremlin is expressed during embryonic development and under different pathologic conditions, including cancer. Gremlin is a proangiogenic protein belonging to the cystine-knot superfamily that includes transforming
Ballmer-Hofer K   +7 more
core   +1 more source

Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model

open access: yesVeterinární Medicína, 2016
Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are platelet concentrates which have been used to improve healing and regeneration of damaged tissues.
J. Vokurka   +4 more
doaj   +1 more source

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