Results 251 to 260 of about 398,069 (306)

A Periosteum‐Inspired Janus Piezoelectric Scaffold Using Bioenergetic‐Driven H‐Type Vascularization for Diabetic Bone Regeneration

Advanced Science, EarlyView.
A periosteum‐inspired Janus piezoelectric scaffold converts micromechanical forces into electrical signals and synergizes with controlled resveratrol release. This dual action reprograms endothelial metabolism, drives H‑type vessel formation, and restores bone–vessel coupling in diabetic bone defects.
Kai Wang, Kai Jiang
wiley   +1 more source

Bioinspired Polymeric Scaffolds for Improvement of Angiogenesis and Tissue Engineering: A Review. [PDF]

Polymers (Basel)
Jigar V, Nensi R, Puja V, Prajapati B, Panraksa P, Singh S, Chittasupho C.   +6 more
europepmc   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source

Immunosuppression and vascular remodeling after liver transplantation: Mechanisms, surrogate markers, and modifiable pathways. [PDF]

World J Transplant
Jahangir S, Zohery M, Diaz Lopez C, Hamed JC, Sarfraz S, Ashraf H, Rafiq T, Ali H, Raza M, Dahiya DS, Khalaf M, Ali H.   +11 more
europepmc   +1 more source

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Orchestration of Endothelial and Osteogenic Marker Expression During Osteogenesis. [PDF]

Int J Mol Sci
Chen S, Zhao Y, Chen N, Wu X, Zhang L, Jing Z, Qi L, Cai X, Boström KI, Yao Y.   +9 more
europepmc   +1 more source

Microglia-vascular interactions after spinal cord injury: regulatory mechanisms and therapeutic advances. [PDF]

Front Immunol
Zhao Y, Wang W, Li S, Li M, Zhang W, Lu T, Wang L, Han T, Ren W.   +8 more
europepmc   +1 more source

The Aging Microenvironment Shapes Angiogenic Remodeling in IBD-Associated Colorectal Carcinogenesis. [PDF]

Aging Cell
Duan R, Chen Q, Xu Y, Yan Y, Jiang S.
europepmc   +1 more source

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Vascular endothelial growth factor

The International Journal of Biochemistry & Cell Biology, 1998
Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis in development, in cancer and in other important diseases. VEGF regulates multiple endothelial cell functions including mitogenesis, permeability, vascular tone, and the production of vasoactive molecules.
GILBERT TERESA, CONKLIN DARREL C, HART CHARLES E, NYGAARD SEAN, SHEPPARD PAUL O   +4 more
openaire   +4 more sources