Results 281 to 290 of about 813,839 (343)
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Vascular endothelial growth factor
Ophthalmology, 2007Vascular endothelial growth factor (VEGF) signalling is a key stimulant of tumour neovascular growth, survival and capillary permeability, which are critical to solid tumour progression. The intracellular signalling responses that induce an angiogenic phenotype are dependent upon VEGF binding to specific transmembrane receptors on the endothelium and ...
Neil Swanson, Anthony Gershlick
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Vascular endothelial growth factor
Journal of Neuro-Oncology, 1997Vascular endothelial growth factor (VEGF) is a hypoxia-inducible angiogenesis and vascular permeability factor which is expressed in high amounts in perinecrotic palisading cells in human glioblastomas. In vitro VEGF gene expression is enhanced approximately ten times by hypoxia.
Plate, Karlheinz, Warnke, Peter C.
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Intravitreal vascular endothelial growth factor
Graefe's Archive for Clinical and Experimental Ophthalmology, 2014To evaluate whether a specific pre-analytical stabilization regimen is needed for naïve vitreous taps to detect true values of intrinsic VEGF levels.Fourteen consecutive patients with different vitreomacular pathologies without blood-retina-barrier breakdown were scheduled for standard 23-gauge three-port pars plana vitrectomy, and naïve vitreous taps ...
Thomas, Bertelmann +6 more
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Vascular Endothelial Growth Factor
2003The striking structural and anatomical parallels between the vasculature and the nervous system is reflected by the fact that these two organ systems appear to use related mechanisms during their development. Thus, it is not surprising that an increasing number of vascular biologists and researchers in the neuroscience field are fascinated by molecules
D GABRILOVICH, M DIKOV
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Vascular Endothelial Growth Factor and Vascular Homeostasis
Proceedings of the American Thoracic Society, 2011Vascular endothelial growth factor (VEGF) is the angiogenic factor promoting and orchestrating most, if not all, processes of neovascularization taking place in the embryo and the adult. VEGF is also required to sustain newly formed vessels and plays additional multiple roles in the maintenance and function of certain mature vascular beds ...
Alon, Lazarus, Eli, Keshet
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Vascular endothelial growth factor
The International Journal of Biochemistry & Cell Biology, 1998Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis in development, in cancer and in other important diseases. VEGF regulates multiple endothelial cell functions including mitogenesis, permeability, vascular tone, and the production of vasoactive molecules.
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1999
Distinct cellular processes mediate blood-vessel formation during embryogenesis (Beck and D’Amore 1997; Carmeliet and Collen 1998a; Folkman and D’Amore 1996; Noden 1989; Risau 1997; Wilting and Christ 1996) (Fig. 1). Initially, mesodermal cells differentiate in situ into early haemangioblasts and form cellular aggregates (blood islands), in which the ...
P, Carmeliet, D, Collen
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Distinct cellular processes mediate blood-vessel formation during embryogenesis (Beck and D’Amore 1997; Carmeliet and Collen 1998a; Folkman and D’Amore 1996; Noden 1989; Risau 1997; Wilting and Christ 1996) (Fig. 1). Initially, mesodermal cells differentiate in situ into early haemangioblasts and form cellular aggregates (blood islands), in which the ...
P, Carmeliet, D, Collen
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Vascular Endothelial Growth Factor and Angiogenesis
Pharmacological Reviews, 2004Angiogenesis is a hallmark of wound healing, the menstrual cycle, cancer, and various ischemic and inflammatory diseases. A rich variety of pro- and antiangiogenic molecules have already been discovered. Vascular endothelial growth factor (VEGF) is an interesting inducer of angiogenesis and lymphangiogenesis, because it is a highly specific mitogen for
Ann, Hoeben +5 more
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Frontiers in Bioscience, 2007
Angiogenesis is a critical process in both physiological development and many pathological processes. Vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) signaling pathway plays a pivotal role in regulating angiogenesis. Many therapeutic agents targeting VEGF and VEGFR are currently in preclinical and clinical development.
Weibo, Cai, Xiaoyuan, Chen
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Angiogenesis is a critical process in both physiological development and many pathological processes. Vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) signaling pathway plays a pivotal role in regulating angiogenesis. Many therapeutic agents targeting VEGF and VEGFR are currently in preclinical and clinical development.
Weibo, Cai, Xiaoyuan, Chen
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