Results 121 to 130 of about 202,499 (165)

Vascular Endothelium and Blood Flow

2006
Major advances have been made over the last decade towards the elucidation of the molecular mechanisms involved in the endothelium-dependent regulation of vascular tone and blood flow. While the primary endothelium-derived vasodilator autacoid is nitric oxide, it is clear that epoxyeicosatrienoic acids and other endothelium-derived hyperpolarising ...
R, Busse, I, Fleming
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Hemodynamics and the Vascular Endothelium

Journal of Biomechanical Engineering, 1993
The endothelium, once thought to be a passive, non-thrombogenic barrier, is now recognized as being a dynamic participant in vascular biology and pathobiology. Part of its dynamic nature is due to the influence of the mechanical environment imposed by the hemodynamics of the vascular system.
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Regulated Secretion in Vascular Endothelium

1991
Eukaryotic cells secrete proteins through both regulated and constitutive pathways (1). In the regulated pathway, exocytosis of stored material is coupled to an external stimulus which produces transient elevations in [Ca2+]i, cAMP or other secondary messengers (2, 3).
B M, Ewenstein, B C, Jacobson, K A, Birch   +2 more
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The Vascular Endothelium in Scleroderma

International Reviews of Immunology, 1995
(1995). The Vascular Endothelium in Scleroderma. International Reviews of Immunology: Vol. 12, No. 2-4, pp. 227-245.
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Eicosanoids and the Vascular Endothelium

2006
Cyclooxygenase (COX) enzymes catalyse the biotransformation of arachidonic acid to prostaglandins which subserve important functions in cardiovascular homeostasis. Prostacyclin (PGI2) and prostaglandin (PG)E2, dominant products of COX activityin macro- and microvascular endothelial cells, respectively, in vitro, modulate the interaction of blood cells ...
K, Egan, G A, FitzGerald
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Leukocyte Adhesion to Vascular Endothelium

Journal of Reconstructive Microsurgery, 1992
Leukocyte adhesion and emigration are controlled by soluble mediators and effected by various adhesion molecules. Currently, three major families of adhesion receptors are known to contribute to this process: integrins, vascular selectins, and immunoglobulin-like receptors. These adhesion systems are not additive and mutually replaceable, but appear to
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Immunobiology of human vascular endothelium

Immunologic Research, 1999
The author's laboratory studies interactions between human T lymphocytes and vascular endothelial cells (EC). Our work is organized around three hypotheses. First, we propose that vascular EC can initiate secondary (i.e., recall) immune reactions by presenting antigenic peptide-major histocompatibility complex (MHC) complexes to those circulating ...
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The Vascular Endothelium in Hypertension

2006
The vascular endothelium plays a fundamental role in the basal and dynamic regulation of the circulation. Thus, it has a crucial role in the pathogenesis of hypertension. A spectrum of vasoactive substances is synthesised in the endothelium; of these, nitric oxide (NO), prostacyclin (PGI2) and endothelin (ET)-1 are the most important.
L E, Spieker, A J, Flammer, T F, Lüscher   +2 more
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Vascular Endothelium and Hypovolemic Shock

Current Vascular Pharmacology, 2016
Endothelium is a site of metabolic activity and has a major reservoir of multipotent stem cells. It plays a vital role in the vascular physiological, pathophysiological and reparative processes. Endothelial functions are significantly altered following hypovolemic shock due to ischemia of the endothelial cells and by reperfusion due to resuscitation ...
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Vascular endothelium, haemostasis and thrombosis

Blood Reviews, 1988
The vascular endothelium consists of a monolayer of cells. Integrity of the endothelium is essential for maintenance of blood fluidity as the subendothelium is composed of structures which rapidly activate platelets and coagulation. Recent research indicates that the endothelium is involved in other processes particularly vasoactivity, immune reactions
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