Results 11 to 20 of about 202,499 (165)
Molecular Therapy: Nucleic Acids, 2016 The regulation of function of endothelial cell–cell junctions is fundamental in sustaining vascular integrity. The polycistronic microRNA (miR) complexes containing miR-23a-27a-24-2, and 23b-27b-24-1 are predicted to target the majority of major ...
Jia Li +6 more
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Extracellular matrix and nitric oxide based functional coatings for vascular stents
Engineered Regeneration, 2022 Cardiovascular diseases cause huge morbidity and mortality worldwide. Recently, vascular stents have been most frequently used to treat cardiovascular diseases thanks to their effectiveness at dilating blood vessels and maintaining the circulation of ...
Quhan Cheng +5 more
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Redox Biology, 2017 Tobacco smoking and hemodynamic forces are key stimuli in the development of endothelial dysfunction and atherosclerosis. High laminar flow has an atheroprotective effect on the endothelium and leads to a reduced response of endothelial cells to ...
Sindy Giebe +6 more
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Nanomechanics of vascular endothelium [PDF]
Cell and Tissue Research, 2014 The mechanical characteristics of endothelial cells reveal four distinct compartments, namely glycocalyx, cell cortex, cytoplasm and nucleus. There is accumulating evidence that endothelial nanomechanics of these individual compartments control vascular physiology.
Fels, Johannes +4 more
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Anales de la Facultad de Medicina, 2014 Over the last 40 years, research on the vascular endothelium has provided important clues for the understanding of vascular disease. This new knowledge is finding its way into clinical medicine.
Salvador Moncada
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Journal of Pharmacological Sciences, 2011 .: Endothelium regulates vascular tone via release of endothelium-derived relaxing factors (EDRF) including nitric oxide (NO), prostaglandin I2 (PGI2), and endothelium-derived hyperpolarizing factor (EDHF).
Xin Jin +6 more
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Organ-Specific Endothelial Dysfunction Following Total Body Irradiation Exposure
Toxics, 2022 As the single cell lining of the heart and all blood vessels, the vascular endothelium serves a critical role in maintaining homeostasis via control of vascular tone, immune cell recruitment, and macromolecular transit.
Guru Prasad Sharma, Heather A. Himburg
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Endothelium-Derived Relaxing Factor–Mediated Vasodilation in Mouse Mesenteric Vascular Beds
Journal of Pharmacological Sciences, 2012 The endothelium in rat mesenteric vascular beds has been demonstrated to regulate vascular tone by releasing mainly endothelium-derived hyperpolarizing factor (EDHF), which is involved in the activation of K+ channels and gap-junctions.
Hiroki Fujiwara +7 more
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Viruses, 2022 Influenza virus infection may cause endothelial activation and dysfunction. However, it is still not known to what extent the influenza virus can dysregulate the expression of various endothelial proteins. The aim of the study is to identify the level of
Vladimir Marchenko +4 more
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Vascular endothelium in diabetes [PDF]
American Journal of Physiology-Renal Physiology, 2017 Three decades ago a revolutionary idea was born that ascribed to dysfunctional endothelia some manifestations of diabetes, the Steno hypothesis, so named after the Steno Diabetes Center, Gentofte, in Denmark. Here I briefly outline the accomplishments accrued in the past 15 years to buttress this hypothesis.
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