Results 11 to 20 of about 200,188 (263)

Malaria and Vascular Endothelium

Arquivos Brasileiros de Cardiologia, 2014
Involvement of the cardiovascular system in patients with infectious and parasitic diseases can result from both intrinsic mechanisms of the disease and drug intervention.
Aristóteles Comte de Alencar Filho, Marcus Vinícius Guimarães de Lacerda, Katashi Okoshi, Marina Politi Okoshi   +3 more
doaj   +6 more sources

Mechanosensing by Vascular Endothelium. [PDF]

Annu Rev Physiol
Mechanical forces influence different cell types in our bodies. Among the earliest forces experienced in mammals is blood movement in the vascular system. Blood flow starts at the embryonic stage and ceases when the heart stops. Blood flow exposes endothelial cells (ECs) that line all blood vessels to hemodynamic forces.
Lim XR, Harraz OF.
europepmc   +3 more sources

Extracellular matrix and nitric oxide based functional coatings for vascular stents

Engineered Regeneration, 2022
Cardiovascular diseases cause huge morbidity and mortality worldwide. Recently, vascular stents have been most frequently used to treat cardiovascular diseases thanks to their effectiveness at dilating blood vessels and maintaining the circulation of ...
Quhan Cheng, Muhammad Shafiq, Muhammad Rafique, Li Shen, Xiumei Mo, Kai Wang   +5 more
doaj   +1 more source

Cigarette smoke extract counteracts atheroprotective effects of high laminar flow on endothelial function

Redox Biology, 2017
Tobacco smoking and hemodynamic forces are key stimuli in the development of endothelial dysfunction and atherosclerosis. High laminar flow has an atheroprotective effect on the endothelium and leads to a reduced response of endothelial cells to ...
Sindy Giebe, Natalia Cockcroft, Katherine Hewitt, Melanie Brux, Anja Hofmann, Henning Morawietz, Coy Brunssen   +6 more
doaj   +1 more source

Nanomechanics of vascular endothelium [PDF]

Cell and Tissue Research, 2014
The mechanical characteristics of endothelial cells reveal four distinct compartments, namely glycocalyx, cell cortex, cytoplasm and nucleus. There is accumulating evidence that endothelial nanomechanics of these individual compartments control vascular physiology.
Fels, Johannes, Jeggle, Pia, Liashkovich, Ivan, Peters, Wladimir, Oberleithner, Hans   +4 more
openaire   +2 more sources

The vascular endothelium

Anales de la Facultad de Medicina, 2014
Over the last 40 years, research on the vascular endothelium has provided important clues for the understanding of vascular disease. This new knowledge is finding its way into clinical medicine.
Salvador Moncada
doaj   +1 more source

New Molecular Mechanisms for Cardiovascular Disease: Contribution of Endothelium-Derived Hyperpolarizing Factor in the Regulation of Vasoconstriction in Peripheral Resistance Arteries

Journal of Pharmacological Sciences, 2011
.: Endothelium regulates vascular tone via release of endothelium-derived relaxing factors (EDRF) including nitric oxide (NO), prostaglandin I2 (PGI2), and endothelium-derived hyperpolarizing factor (EDHF).
Xin Jin, Yukiko Satoh-Otonashi, Yoshito Zamami, Shingo Takatori, Narumi Hashikawa-Hobara, Yoshihisa Kitamura, Hiromu Kawasaki   +6 more
doaj   +1 more source

Organ-Specific Endothelial Dysfunction Following Total Body Irradiation Exposure

Toxics, 2022
As the single cell lining of the heart and all blood vessels, the vascular endothelium serves a critical role in maintaining homeostasis via control of vascular tone, immune cell recruitment, and macromolecular transit.
Guru Prasad Sharma, Heather A. Himburg
doaj   +1 more source

Endothelium-Derived Relaxing Factor–Mediated Vasodilation in Mouse Mesenteric Vascular Beds

Journal of Pharmacological Sciences, 2012
The endothelium in rat mesenteric vascular beds has been demonstrated to regulate vascular tone by releasing mainly endothelium-derived hyperpolarizing factor (EDHF), which is involved in the activation of K+ channels and gap-junctions.
Hiroki Fujiwara, Yoshihiro Wake, Narumi Hashikawa-Hobara, Kento Makino, Shingo Takatori, Yoshito Zamami, Yoshihisa Kitamura, Hiromu Kawasaki   +7 more
doaj   +1 more source

Influenza A(H1N1)pdm09 Virus Alters Expression of Endothelial Factors in Pulmonary Vascular Endothelium in Rats

Viruses, 2022
Influenza virus infection may cause endothelial activation and dysfunction. However, it is still not known to what extent the influenza virus can dysregulate the expression of various endothelial proteins. The aim of the study is to identify the level of
Vladimir Marchenko, Darya Mukhametdinova, Irina Amosova, Dmitry Lioznov, Irina Zhilinskaya   +4 more
doaj   +1 more source