Results 21 to 30 of about 202,499 (165)
Contribution of Oxidative Stress to Endothelial Dysfunction in Hypertension
Frontiers in Physiology, 2012 Endothelial dysfunction is the hallmark of hypertension, which is a multifactorial disorder. In the cardiovascular system reactive oxygen species play a pivotal role in controlling the endothelial function and vascular tone.
Bruno Rodrigues Silva +2 more
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Hydrogen Peroxide Is an Endothelium-Derived Hyperpolarizing Factor in Animals and Humans
Journal of Pharmacological Sciences, 2003 Vascular endothelium plays an important role in maintaining vascular homeostasis by synthesizing and releasing several vasodilating factors, such as prostacyclin, nitric oxide (NO), and a yet unidentified endothelium-derived hyperpolarizing factor (EDHF).
Matoba Tetsuya, Hiroaki Shimokawa
doaj +1 more source
AntioxidantsThe NADPH oxidase NOX4 that releases H2O2 can mediate vasoprotective mechanisms under pathophysiological conditions in conductive arteries. However, the role of NOX4 in resistance arteries and in perivascular adipose tissue is not well understood.
Patrick Diaba-Nuhoho +4 more
doaj +1 more source
ENDOTHELIUM-DEPENDENT VASCULAR REACTIVITY IN DIABETES MELLITUS TYPE 2
Клиническая практика, 2017 The review presents modern information on the development of disorders of endothelium-dependent vascular reactivity in diabetes mellitus (DM) type 2. In type 2 DM, disorders of endothelium-dependent vascular reactivity associated with hyperglycemia and ...
K Yu Nikolaev +3 more
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NADPH Oxidase 4: Crucial for Endothelial Function under Hypoxia—Complementing Prostacyclin
AntioxidantsAim: The primary endothelial NADPH oxidase isoform 4 (NOX4) is notably induced during hypoxia, with emerging evidence suggesting its vasoprotective role through H2O2 production. Therefore, we aimed to elucidate NOX4′s significance in endothelial function
Heike Brendel +9 more
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THE SENSITIVITY OF VASCULAR ENDOTHELIUM AND ITS PREDICTORS IN PATIENTS WITH CARDIOVASCULAR PATHOLOGY
Кардиоваскулярная терапия и профилактика, 2014 Aim. To estimate the role of endogenous metabolic factors in formation of vascular endothelium reactivity in patients with different genesis cardiovascular regulation disorders.Materials and methods.
E. O. Andreeva +3 more
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Endocardial Endothelium and Cardiac Contractility
Journal of Biological Research, 2003 Following the observation by Furchgott and Zawadski (1980) about the obligatory role of vascular endothelium in vasomotor tone, several in vitro and in vivo studies provided experimental evidences that cardiac endothelium plays a similar role in ...
G. Alloatti
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The Cell Surface, 2023 Multiple blood-borne pathogens infecting mammals establish close interactions with the host vascular endothelium as part of their life cycles. In this work, we investigate differences in the interactions of three Trypanosoma species: T.
Sara Silva Pereira +4 more
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, 2018 Over the last 40 years, research on the vascular endothelium has provided important clues for the understanding of vascular disease. This new knowledge is finding its way into clinical medicine. In this review we deal with some areas where significant advances in the prevention and treatment of cardiovascular research has been achieved and with some of
openaire +3 more sources
AntioxidantsEndothelin-1 is a key regulator of vascular tone and blood pressure in health and disease. We have recently found that ET-1 production in human microvascular endothelial cells (HMECs) can be promoted by angiotensin II (Ang II) through a novel mechanism ...
Michael Adu-Gyamfi +12 more
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