Results 31 to 40 of about 202,499 (165)
VASOMOTOR FUNCTION OF THE ENDOTHELIUM IN PATIENTS WITH CHRONIC KIDNEY DISEASE AND HYPERTENSION
Український Журнал Нефрології та Діалізу, 2017 Investigation of the functional state of the vascular endothelium contributes to the further study of the mechanisms of development and pharmacological correction, particularly in hypertensive patients with chronic kidney disease.
N. V. Demikhova +3 more
doaj +1 more source
Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice. [PDF]
PLoS ONE, 2016 Endothelial-mesenchymal transition (EndMT) drives endothelium to contribute to normal development and disease processes. Here, we report that EndMTs occur in the diabetic endothelium of Ins2Akita/wt mouse, and show that induction of sex determining ...
Pierre J Guihard +5 more
doaj +1 more source
Bioactive Materials, 2023 Native-like endothelium regeneration is a prerequisite for material-guided small-diameter vascular regeneration. In this study, a novel strategy is proposed to achieve phase-adjusted endothelial healing by step-wise modification of parallel-microgroove ...
Bingcheng Yi +5 more
doaj +1 more source
Novel Therapies Targeting Vascular Endothelium
Endothelium, 2006 Endothelial dysfunction has been identified as a major mechanism involved in all the stages of atherogenesis. Evaluation of endothelial function seems to have a predictive role in humans, and therapeutic interventions improving nitric oxide bioavailability in the vasculature may improve the long-term outcome in healthy individuals, high-risk subjects ...
Tousoulis, Dimitris +6 more
openaire +3 more sources
Journal of Pharmacological Sciences, 2009 We previously reported that endothelium-derived hyperpolarizing factor (EDHF)– mediated response time-dependently suppressed methoxamine-induced vasoconstriction in mesenteric vascular beds isolated from 8-week-old rats.
Xin Jin +8 more
doaj +1 more source
Physiological Reports, 2021 The health benefits of the natural polyphenol trans‐resveratrol may play an important role in preventing a variety of diseases. Resveratrol has been shown to reduce blood pressure and improve metabolic diseases such as type 2 diabetes mellitus and ...
Ian R. VanAntwerp +3 more
doaj +1 more source
Vascular Endothelium in Neonatal Sepsis: Basic Mechanisms and Translational Opportunities
Frontiers in Pediatrics, 2019 Neonatal sepsis remains a major health issue worldwide, especially for low-birth weight and premature infants, with a high risk of death and devastating sequelae.
Carlo Pietrasanta +18 more
doaj +1 more source
Microcirculatory disorders in scleroderma systematica: an association with vascular wall stiffness
Научно-практическая ревматология, 2013 Objective: to study the specific features of regulation of peripheral vascular tone and their association with the endothelial structure and function of large vessels in patients with scleroderma systematica (SDS). Subjects and methods. The investigation
Ulyana Yuryevna Ruzhentsova
doaj +1 more source
Cells, 2020 Clinical studies have established a connection between oxidative stress, aging, and atherogenesis. These factors contribute to senescence and inflammation in the endothelium and significant reductions in endothelium-dependent vasoreactivity in aged ...
Ellen E. Salmon +2 more
doaj +1 more source
PLoS ONE, 2019 In healthy arteries, blood flow is regulated by microvascular tone assessed by changes in blood flow volume and vascular resistance to endothelium-dependent and -independent vasodilators.
Scott Kinlay +8 more
doaj +1 more source