Results 51 to 60 of about 1,018,275 (289)

Double-Layered Circular Advancement Flap for Reconstruction of Inguinal Defects

Turkish Journal of Plastic Surgery, 2017
Objective: Vascular graft infections are rare complications but can lead to life-threatening outcomes for the patient. Conventional treatment methods are the removal of the vascular graft and an extra-anatomic by-pass procedure.
Enver Arpaci, Serdar Altun
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Complex endovascular aortic repair after infected vascular graft reconstruction with bovine pericardial graft: A case report and review of the literature

JVS-Vascular Insights
This report describes the management of a vascular graft infection using a bovine pericardial graft and its subsequent use as a distal landing zone to perform complex endovascular aortic repair.
Kay C.G. Smeenk, BSc, Emiel W.M. Huistra, BSc, Ignace F.J. Tielliu, MD, PhD, Clark J. Zeebregts, MD, PhD   +3 more
doaj   +1 more source

Determinants of successful synthetic hemodialysis vascular access graft placement [PDF]

, 2003
Objective: Synthetic vascular grafts, the most common type of permanent dialysis graft used in the United States, are associated with great morbidity and expense.
Knauss, Jill, Brayman, Kenneth, Joffe, Marshall, Burns, J.Eileen, Rosas, Sylvia E., Feldman, Harold I.   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Computer-assisted ex vivo, normothermic small bowel perfusion [PDF]

, 2000
Background: In the present study, a technique for computer-assisted, normothermic, oxygenated, ex vivo, recirculating small bowel perfusion was established as a tool to investigate organ pretreatment protocols and ischemia/reperfusion phenomena.
Theodorou, D., Hammer, C., Schildberg, Friedrich Wilhelm, Eder, M., Land, W., Stangl, M. J., Krapp, J.   +6 more
core   +1 more source

Patterns of vascular graft infection in 18F-FDG PET/CT [PDF]

, 2020
BACKGROUND: 18F-FDG PET/CT has become an important tool in diagnosis of prosthetic vascular graft infections (PVGI). The aim of the study was to identify the patterns of vascular graft infection in 18F-FDG PET/CT.
Zubilewicz, Tomasz; Chair and Department of Vascular Surgery and Angiology, Medical University of Lublin, Nocuń, Anna; Chair and Department of Nuclear Medicine, Medical University of Lublin, Wolski, Andrzej; Department of Interventional Radiology and Neuroradiology, Medical University of Lublin, Lublin, Poland, Terelecki, Piotr; Chair and Department of Vascular Surgery and Angiology, Medical University of Lublin, Chrapko, Beata E.; Chair and Department of Nuclear Medicine, Medical University of Lublin, Chrapko, Marek; Chair and Department of Vascular Surgery and Angiology, Medical University of Lublin, Mitura, Jakub; Chair and Department of Nuclear Medicine, Medical University of Lublin, Stefaniak, Bogusław; Chair and Department of Nuclear Medicine, Medical University of Lublin   +7 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

NK Cells: Not Just Followers But Also Initiators of Chronic Vascular Rejection

Transplant International
Chronic graft rejection represents a significant threat to long-term graft survival. Early diagnosis, understanding of the immunological mechanisms and appropriate therapeutic management are essential to improve graft survival and quality of life for ...
Mathilde Chambon, Alice Koenig, Alice Koenig, Alice Koenig   +3 more
doaj   +1 more source