Results 61 to 70 of about 1,018,275 (289)

Moderate LMWH Anticoagulation Improves Success Rate of Hind Limb Allotransplantation in Mice

Plastic and Reconstructive Surgery, Global Open, 2023
Background:. The mouse hind limb model represents a powerful research tool in vascularized composite tissue allotransplantation, but its applicability is limited due to poor graft survival (62%–83%).
Barbara Kern, MD, Muhammad-Imtiaz Ashraf, PhD, Anja Reutzel-Selke, PhD, Joerg Mengwasser, PhD, Dietrich Polenz, Edward Michaelis, MD, Johann Pratschke, MD, PhD, Stefan G. Tullius, MD, PhD, Christian Witzel, MD, PhD, Igor M. Sauer, MD, PhD   +9 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Preliminary In Vivo Evaluation of a Hybrid Armored Vascular Graft Combining Electrospinning and Additive Manufacturing Techniques

, 2016
In this study, we tested in vivo effectiveness of a previously developed poly-L-lactide/poly-8-caprolactone armored vascular graft releasing heparin. This bioprosthesis was designed in order to overcome the main drawbacks of tissue-engineered vascular ...
Federico De Marco, Fraser W.H. Sutherland, Massimo Chello, Francesco Nappi, Cristiano Spadaccio, Alberto Rainer, Pietro Sedati, Marcella Trombetta   +7 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Application of self-sealing vascular graft and expanded polytetrafluoroethylene vascular graft in establishment of vascular access

Linchuang shenzangbing zazhi, 2019
Objective To compare application effects of self-sealing vascular graft(Acuseal) and expanded polytetrafluoroethylene(ePTFE) vascular grafts in establishment of arteriovenous fistula in maintenance hemodialysis patients, so as to provide reference for ...
肖光辉, 詹申, 王玉柱, 张丽红
doaj  

Silk Fibroin Vascular Graft: From Design to In Vitro and In Vivo Test

, 2019
Silk Fibroin Vascular Graft: From Design to In Vitro and In Vivo ...
Freddi, G, Settembrini, A, Settembrini, P, Dal Pra, I, Chiarini, A, Alessandrino, A   +5 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Half of synthetic conduits are discarded in open cardiac and vascular surgeries

JVS-Vascular Insights
Objective: This report aims to quantify discarded vascular graft material during cardiovascular surgeries and evaluate the associated financial implications.
David Derish, MDCM, Kent MacKenzie, MDCM, FRCPSC, Kevin Lachapelle, MDCM, FACS, FRCPSC   +2 more
doaj   +1 more source

Endovascular rescue of long-term vascular graft implants and need for continuous surveillance

Journal of Vascular Surgery Cases and Innovative Techniques, 2018
We present two cases of vascular graft degradation after long-term implantation. In both patients, endovascular techniques were employed to effect continued graft patency and function.
Brian M. Leoce, BS, Herbert Dardik, MD, FACS, Phillip Bahramipour, MD, Thomas R. Bernik, MD, FACS   +3 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source