Results 1 to 10 of about 1,180,293 (286)

Higher Serum Leptin Levels Are Associated with Impaired Vascular Reactivity in Patients with Type 2 Diabetes Mellitus [PDF]

Biomedicines
Background/Objectives: Endothelial dysfunction represents an early stage of vascular injury in type 2 diabetes mellitus (T2DM) and contributes to increased cardiovascular risk. Leptin, a hormone involved in metabolic and inflammatory regulation, has been
I-Min Su, Shih-Yuan Ye, Jer-Chuan Li, Du-An Wu, Bang-Gee Hsu   +4 more
doaj   +2 more sources

Hyperleptinemia Is a Risk Factor for the Development of Vascular Reactivity Impairment in Patients with Hypertension [PDF]

Medicina
Background and Objectives: Endothelial dysfunction represents an early indicator of cardiovascular disease in individuals with hypertension. Leptin, an adipokine that regulates vascular homeostasis and metabolism, has been linked to vascular impairment ...
I-Min Su, Li-Liang Chuang, Ji-Hung Wang, Bang-Gee Hsu   +3 more
doaj   +2 more sources

Elevated Serum Trimethylamine N-Oxide Predicts Impaired Vascular Reactivity in Patients with Hypertension [PDF]

Diagnostics
Background/Objectives: Trimethylamine N-oxide (TMAO), a gut microbiota-derived metabolite influenced by diet, has been linked to cardiovascular disease. Endothelial dysfunction, an early sign of vascular damage, is common in hypertension.
I-Min Su, Ji-Hung Wang, Chin-Hung Liu, Bang-Gee Hsu   +3 more
doaj   +2 more sources

Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from vascular reactivity index assessment [PDF]

Renal Failure
Background Patients with maintenance hemodialysis (MHD) present endothelial dysfunction (ED), which is characterized by impaired vasodilation and a pro-inflammatory state. Lipoprotein(a) (Lp(a)) has pro-inflammatory and pro-atherogenic properties.
Wen-Lin Lo, Bang-Gee Hsu, Chih-Hsien Wang, Yu-Lin Lin, Chiu-Huang Kuo, Yu-Hsien Lai   +5 more
doaj   +2 more sources

Serum Osteoprotegerin Levels and the Vascular Reactivity Index in Patients with Hypertension [PDF]

Medicina, 2023
Background and Objectives: Osteoprotegerin (OPG), a soluble glycoprotein found in serum, has been associated with both the presence and severity of atherosclerosis.
Yen-Liang Chen, Po-Yu Huang, Jen-Pi Tsai, Ji-Hung Wang, Bang-Gee Hsu   +4 more
doaj   +2 more sources

Melatonin Reduces Oxidative Stress in the Right Ventricle of Newborn Sheep Gestated under Chronic Hypoxia

Antioxidants, 2021
Pulmonary arterial hypertension of newborns (PAHN) constitutes a critical condition involving both severe cardiac remodeling and right ventricle dysfunction. One main cause of this condition is perinatal hypoxia and oxidative stress. Thus, it is a public
Alejandro Gonzaléz-Candia, Pamela V. Arias, Simón A. Aguilar, Esteban G. Figueroa, Roberto V. Reyes, Germán Ebensperger, Aníbal J. Llanos, Emilio A. Herrera   +7 more
doaj   +1 more source

Cardioprotective Antioxidant and Anti-Inflammatory Mechanisms Induced by Intermittent Hypobaric Hypoxia

Antioxidants, 2022
More than 80 million people live and work (in a chronic or intermittent form) above 2500 masl, and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated that 100,000 people work in high-altitude shifts, where stays in the ...
Alejandro González-Candia, Alejandro A. Candia, Adolfo Paz, Fuad Mobarec, Rodrigo Urbina-Varela, Andrea del Campo, Emilio A. Herrera, Rodrigo L. Castillo   +7 more
doaj   +1 more source

Gestational Hypoxia and Blood-Brain Barrier Permeability: Early Origins of Cerebrovascular Dysfunction Induced by Epigenetic Mechanisms

Frontiers in Physiology, 2021
Fetal chronic hypoxia leads to intrauterine growth restriction (IUGR), which is likely to reduce oxygen delivery to the brain and induce long-term neurological impairments.
Emilio A. Herrera, Alejandro González-Candia   +1 more
doaj   +1 more source

Serum myostatin level is a positive predictor of endothelial function measured by digital thermal monitoring of vascular reactivity in kidney transplantation patients

Tzu Chi Medical Journal, 2022
Objectives: Myostatin is a myokine predominantly expressed and secreted in skeletal muscle in response to stimulations, including oxidative stress or inflammation.
Hsiu-Hsien Lin, Ching-Chun Ho, Yen-Cheng Chen, Guan-Jin Ho, Bang-Gee Hsu, Ming-Che Lee   +5 more
doaj   +1 more source

Cardioprotective Solutions Exposure For 1 Hour in Hypoxia and Low Temperatures Affects Vascular Reactivity Differently [PDF]

Brazilian Journal of Cardiovascular Surgery, 2021
Introduction: Heart preservation benefits cardiac performance after operations decreasing morbidity but the contribution of the vascular reactivity has been neglected.
Priscila Rossi de Batista, Dalton Valentim Vassallo, Maylla Ronacher Simões, Melchior Luiz Lima   +3 more
doaj   +1 more source