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Hyperleptinemia Is a Risk Factor for the Development of Vascular Reactivity Impairment in Patients with Hypertension [PDF]

open access: yesMedicina
Background and Objectives: Endothelial dysfunction represents an early indicator of cardiovascular disease in individuals with hypertension. Leptin, an adipokine that regulates vascular homeostasis and metabolism, has been linked to vascular impairment ...
I-Min Su   +3 more
doaj   +2 more sources

Elevated Serum Trimethylamine N-Oxide Predicts Impaired Vascular Reactivity in Patients with Hypertension [PDF]

open access: yesDiagnostics
Background/Objectives: Trimethylamine N-oxide (TMAO), a gut microbiota-derived metabolite influenced by diet, has been linked to cardiovascular disease. Endothelial dysfunction, an early sign of vascular damage, is common in hypertension.
I-Min Su   +3 more
doaj   +2 more sources

Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from vascular reactivity index assessment [PDF]

open access: yesRenal Failure
Background Patients with maintenance hemodialysis (MHD) present endothelial dysfunction (ED), which is characterized by impaired vasodilation and a pro-inflammatory state. Lipoprotein(a) (Lp(a)) has pro-inflammatory and pro-atherogenic properties.
Wen-Lin Lo   +5 more
doaj   +2 more sources

Serum Osteoprotegerin Levels and the Vascular Reactivity Index in Patients with Hypertension [PDF]

open access: yesMedicina, 2023
Background and Objectives: Osteoprotegerin (OPG), a soluble glycoprotein found in serum, has been associated with both the presence and severity of atherosclerosis.
Yen-Liang Chen   +4 more
doaj   +2 more sources

Effects of ouabain on vascular reactivity [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 1997
Ouabain is an endogenous substance occurring in the plasma in the nanomolar range, that has been proposed to increase vascular resistance and induce hypertension. This substance acts on the a-subunit of Na+,K+-ATPase inhibiting the Na+-pump activity.
Vassallo D.V.   +3 more
doaj   +4 more sources

Serum N-Terminal Pro-B-Type Natriuretic Peptide Level is Negatively Associated with Vascular Reactivity Index by Digital Thermal Monitoring in Patients with Hypertension [PDF]

open access: yesReviews in Cardiovascular Medicine
Background: B-type natriuretic peptide (BNP) coordinates endothelial homeostasis and remodeling, with endothelial dysfunction associated with cardiovascular mortality in the general population without heart failure.
Chien-Hao Hsiao   +3 more
doaj   +2 more sources

Cerebral Vascular Reactivity in Frail Older Adults with Vascular Cognitive Impairment

open access: yesBrain Sciences, 2019
Background: Frailty, a state of increased vulnerability, could play a role in the progression of vascular dementia. We aim to describe the changes in cerebrovascular reactivity of older adults with frailty and vascular-type mild cognitive impairment ...
Sara G. Aguilar-Navarro   +6 more
doaj   +3 more sources

Melatonin Reduces Oxidative Stress in the Right Ventricle of Newborn Sheep Gestated under Chronic Hypoxia

open access: yesAntioxidants, 2021
Pulmonary arterial hypertension of newborns (PAHN) constitutes a critical condition involving both severe cardiac remodeling and right ventricle dysfunction. One main cause of this condition is perinatal hypoxia and oxidative stress. Thus, it is a public
Alejandro Gonzaléz-Candia   +7 more
doaj   +1 more source

Cardioprotective Antioxidant and Anti-Inflammatory Mechanisms Induced by Intermittent Hypobaric Hypoxia

open access: yesAntioxidants, 2022
More than 80 million people live and work (in a chronic or intermittent form) above 2500 masl, and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated that 100,000 people work in high-altitude shifts, where stays in the ...
Alejandro González-Candia   +7 more
doaj   +1 more source

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