Results 51 to 60 of about 5,143,177 (255)

Increased serum galectin-3 level is associated with endothelial dysfunction and cardiovascular events in patients with hypertension

Heliyon
Background: Endothelial dysfunction can lead to various harmful cardiovascular complications. The importance of galectin-3 (Gal-3) has been proposed in some cardiac diseases related to chronic inflammation.
Hui-Sheng Wang, Bang-Gee Hsu, Ji-Hung Wang, Chiu-Fen Yang   +3 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Difference between ejection times measured at two different peripheral locations as a novel marker of vascular stiffness. [PDF]

PLoS ONE, 2017
Pulse wave velocity (PWV) has been recommended as an arterial damage assessment tool and a surrogate of arterial stiffness. However, the current technology does not allow to measure PWV both continuously and in real-time.
Yurie Obata, Pavel Ruzankin, Dan E Berkowitz, Jochen Steppan, Viachaslau Barodka   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Endothelium-independent effect of CNP on vascular reactivity.

, 2016
Endothelium-independent effect of CNP on vascular reactivity.
Carolina Caniffi (444744), María L. Sueiro (3391457), María A. Costa (3391460), Cristina Arranz (444749), Flavia M. Cerniello (3391451), María N. Gobetto (3391454)   +5 more
core   +1 more source

Association between NT-pro-BNP levels and endothelial dysfunction assessed by digital thermal monitoring in patients with coronary artery disease

Frontiers in Cardiovascular Medicine
ObjectiveEndothelial dysfunction is a key mechanism in the progression of coronary artery disease (CAD). N-terminal pro-B-type natriuretic peptide (NT-pro-BNP), a biomarker of myocardial wall stress, has been associated with vascular abnormalities beyond
Ji-Hung Wang, Ji-Hung Wang, Ji-Hung Wang, I-Min Su, I-Min Su, I-Min Su, Bang-Gee Hsu, Bang-Gee Hsu, Bang-Gee Hsu, Bang-Gee Hsu   +9 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Endothelium-dependent effect of CNP on vascular reactivity.

, 2016
Endothelium-dependent effect of CNP on vascular reactivity.
Carolina Caniffi (444744), María L. Sueiro (3391457), María A. Costa (3391460), Cristina Arranz (444749), Flavia M. Cerniello (3391451), María N. Gobetto (3391454)   +5 more
core   +1 more source

Blunted Microvascular Reactivity in Psoriasis Patients in the Absence of Cardiovascular Disease, as Assessed by Laser Speckle Contrast Imaging

Life, 2022
Psoriasis is associated with accelerated rates of cardiovascular disease (CVD). Laser Speckle Contrast Imaging (LSCI) is a novel, non-interventional technique for the dynamic assessment of microvascular endothelial dysfunction, which represents an early ...
Anastasia Margouta, Panagiota Anyfanti, Antonios Lazaridis, Barbara Nikolaidou, Konstantinos Mastrogiannis, Anastasia Malliora, Aikaterini Patsatsi, Areti Triantafyllou, Stella Douma, Michael Doumas, Eugenia Gkaliagkousi   +10 more
doaj   +1 more source