Results 101 to 110 of about 1,333,578 (308)
BMC Medical ImagingObjective To develop and validate a clinical-radiomics model based on multiparametric MRI for differentiating solitary primary spinal tumors from solitary spinal metastases.
Chenxi Wang +4 more
doaj +1 more source
Thyroid Hormone and Vascular Remodeling
Journal of Atherosclerosis and Thrombosis, 2016 Both hyperthyroidism and hypothyroidism affect the cardiovascular system. Hypothyroidism is known to be associated with enhanced atherosclerosis and ischemic heart diseases. The accelerated atherosclerosis in the hypothyroid state has been traditionally ascribed to atherogenic lipid profile, diastolic hypertension, and impaired endothelial function ...
openaire +3 more sources
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
Advanced Healthcare Materials, EarlyView.This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Complement C3a/C3aR inhibition alleviates the formation of aortic aneurysm in Marfan syndrome mice
BMC Cardiovascular DisordersMutations in fibrillin 1 (FBN1) is the main cause of Marfan syndrome (MFS) with thoracic aortic aneurysm (TAA) as the main complication. Activation of the complement system plays a key role in the formation of thoracic and abdominal aortic aneurysms ...
Fan Zhang +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park +5 more
wiley +1 more source
Arteriogenesis, Angiogenesis and Vascular Remodeling
Understanding the mechanisms responsible for vascular remodeling and growth is of utmost importance to developing the most suitable therapies for vascular occlusive diseases in order to save patients' lives and improve their health. This Reprint provides
core +1 more source
Calcium channel blockers increase the risk of aortic aneurysm and dissection
Nature CommunicationsAortic aneurysm and dissection (AAD) are life-threatening conditions without effective medications. Impaired contractility of vascular smooth muscle cells (VSMCs) is strongly linked to AAD, but the role of calcium channel blockers (CCBs), which directly ...
Tianfeng Ma +19 more
doaj +1 more source
Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers
Advanced Healthcare Materials, EarlyView.Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li +9 more
wiley +1 more source
Molecular Imaging of Angiogenesis and Vascular Remodeling in Cardiovascular Pathology
, 2016 Angiogenesis and vascular remodeling are involved in a wide array of cardiovascular diseases, from myocardial ischemia and peripheral arterial disease, to atherosclerosis and aortic aneurysm.
Reza Golestani +2 more
core +1 more source
STAR ProtocolsSummary: Human pluripotent stem cells (hPSCs) hold great promise for applications in regenerative medicine and disease modeling. Here, we present a protocol for establishing edited hPSC cell lines utilizing visualized orthogonal selective reporters.
Yun Zhao +8 more
doaj +1 more source