Results 141 to 150 of about 1,333,578 (308)

Comparative In Vitro Studies of Materials Properties of Uncoated and Multifunctional/Biocompatible Ultrananocrystalline Diamond (UNCD) Coated‐Bioactive Bovine Nanohydroxyapatite Scaffolds for Transformational Bone Tissue Engineering

open access: yesAdvanced Materials Interfaces, EarlyView.
Research/technology development demonstrated physicochemical/mechanical properties of transformational integration of hydroxyapatite (HAp) scaffolds and HAp scaffolds coated with a unique breakthrough biocompatible ultrananocrystalline diamond (UNCD) coating produced by microwave plasma chemical vapor deposition (MPCVD) process.
Angelica M. Castillo‐Paz   +6 more
wiley   +1 more source

Organelle‐Targeted Photosensitizer‐Loaded Nanodiscs for Improved Tumor Photoimmunotherapy

open access: yesAggregate
Photodynamic therapy (PDT) is a promising cancer treatment with minimal invasiveness and high selectivity, but its efficacy depends heavily on subcellular reactive oxygen species (ROS) localization.
Yunxue Xu   +3 more
doaj   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

open access: yesAdvanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn   +5 more
wiley   +1 more source

Depleting LCAT Aggravates Atherosclerosis in LDLR-deficient Hamster with Reduced LDL-Cholesterol Level

open access: yesJournal of Advanced Research
Introduction: Lecithin cholesterol acyltransferase (LCAT) plays a crucial role in acyl-esterifying cholesterol in plasma, which is essential for reverse cholesterol transport (RCT).
Xiao Lin   +15 more
doaj   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani   +2 more
wiley   +1 more source

Pulmonary vascular remodeling.

open access: yes, 2015
At 8 weeks, lungs were harvested, processed, and stained with Masson’s trichrome to examine pulmonary vascular remodeling. Representative images from A) sham and B-D) embolization models with similar patterns of remodeling, including luminal encroachment
Roger J. Hajjar (142214)   +9 more
core   +1 more source

Apolipoprotein C3 exacerbates vascular calcification by promoting ferroptosis via the TLR2/AMPK pathway in vascular smooth muscle cells

open access: yesRedox Biology
Background: Vascular calcification (VC) is prevalent in patients with chronic renal failure (CRF), and it is closely related to the morbidity and mortality of cardiovascular diseases; however, no medical treatments are available for this condition ...
Zihao Zhou   +18 more
doaj   +1 more source

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

open access: yesAdvanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti   +4 more
wiley   +1 more source

Extrusion‐Based Bioprinting of Living Bioinks for Tissue and Organ Engineering

open access: yesAdvanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting is presented as the most versatile route for fabricating living, heterogeneous tissues. Its ability to combine diverse bioinks, support matrices, and advanced printhead geometries transforms familiar constraints into powerful biofabrication opportunities.
Eric Silberman   +4 more
wiley   +1 more source

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