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Vascular nitric oxide resistance in type 2 diabetes

open access: yesCell Death and Disease, 2023
Vascular nitric oxide (NO•) resistance, manifested by an impaired vasodilator function of NO• in both the macro- and microvessels, is a common state in type 2 diabetes (T2D) associated with developing cardiovascular events and death.
Z. Bahadoran   +3 more
semanticscholar   +2 more sources

Calculating vascular resistances [PDF]

open access: yesClinical Cardiology, 1997
AbstractVascular resistance calculations often affect decisions regarding therapeutic options encountered by physicians and their patients. However, many of the terms, units, and methods used when calculating vascular resistances are ambiguous. This report attempts to clarify some of these ambiguities and suggests methods for predicting normal vascular
J W, Skimming, S, Cassin, W W, Nichols
openaire   +2 more sources

Obesity, Adipose Tissue and Vascular Dysfunction.

open access: yesCirculation Research, 2021
Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity are strongly associated with comorbidities such as hypertension and insulin resistance, which collectively contribute to the development of cardiovascular diseases ...
M. Koenen, M. Hill, P. Cohen, J. Sowers
semanticscholar   +1 more source

Sunitinib resistance in renal cell carcinoma: From molecular mechanisms to predictive biomarkers.

open access: yesDrug resistance updates, 2023
Currently, renal cell carcinoma (RCC) is the most prevalent type of kidney cancer. Targeted therapy has replaced radiation therapy and chemotherapy as the main treatment option for RCC due to the lack of significant efficacy with these conventional ...
Juan Jin   +9 more
semanticscholar   +1 more source

Calcium signals that determine vascular resistance

open access: yesWiley Interdisciplinary Reviews: Systems Biology and Medicine, 2019
Small arteries in the body control vascular resistance, and therefore, blood pressure and blood flow. Endothelial and smooth muscle cells in the arterial walls respond to various stimuli by altering the vascular resistance on a moment to moment basis ...
Matteo Ottolini   +2 more
semanticscholar   +1 more source

Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes

open access: yesDiabetes, obesity and metabolism, 2015
To determine the effects of empagliflozin on blood pressure (BP) and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes mellitus (T2DM).
R. Chilton   +6 more
semanticscholar   +1 more source

An MKP-MAPK protein phosphorylation cascade controls vascular immunity in plants

open access: yesScience Advances, 2022
Global crop production is greatly reduced by vascular diseases. These diseases include bacterial blight of rice and crucifer black rot caused by Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas campestris pv. campestris (Xcc). The molecular mechanisms
Hui Lin   +15 more
semanticscholar   +1 more source

Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.

open access: yesComprehensive Physiology, 2017
Vascular tone of resistance arteries and arterioles determines peripheral vascular resistance, contributing to the regulation of blood pressure and blood flow to, and within the body's tissues and organs.
N. Tykocki, E. Boerman, W. Jackson
semanticscholar   +1 more source

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