Results 1 to 10 of about 969,324 (357)

The anti-atherogenic effects of thiazolidinediones [PDF]

open access: yes, 2007
The thiazolidinediones (TZDs) rosiglitazone (ROS) and pioglitazone (PIO) are insulin-sensitising agents widely used to treat patients with type 2 diabetes mellitus (T2DM). Thiazolidinediones significantly improve glycaemic control in diabetics by reduced
Honisett, Suzy   +2 more
core  

Amiloride reduces portal hypertension in rat liver cirrhosis [PDF]

open access: yes, 2010
Objective This study aimed to investigate the effect of amiloride on portal hypertension. Amiloride is known to inhibit Na(+)/H(+) exchangers on activated hepatic stellate cells.
Beitinger, Frigga   +6 more
core   +1 more source

METOCLOPRAMIDE AND RENAL VASCULAR RESISTANCE

open access: yesBritish Journal of Anaesthesia, 1991
We have studied the effect of i.v. metoclopramide on renal vascular resistance in nine healthy volunteers. Peak systolic and end-diastolic frequencies were measured using duplex Doppler ultrasound of a renal interlobar artery, before and after the administration of i.v. metoclopramide 10 mg, and the resistance index derived.
A R, Manara   +4 more
openaire   +2 more sources

Persuasive antimicrobial stewardship intervention in the context of a KPC outbreak: a controlled interrupted time series analysis

open access: yesAntimicrobial Resistance and Infection Control, 2020
Introduction Antimicrobial resistance is a major public health threat. Antimicrobial stewardship (AMS) is one of the key strategies to overcome resistance, but robust evidence on the effect of specific interventions is lacking.
Nuno Rocha-Pereira   +8 more
doaj   +1 more source

Use of Prostaglandin E1 in Neonates with Severe Persistent Pulmonary Hypertension (PPHN): A Narrative Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Persistent Pulmonary Hypertension of the Newborn (PPHN) is a significant health issue characterised by the inadequate circulatory transitions at birth, subsequent to considerable hypoxaemia and increased Pulmonary Vascular Resistance (PVR).
Ravi Kiran Kumar Reddy   +4 more
doaj   +1 more source

Short-term therapy with rosiglitatzone, a PPAR-¿ agonist improves metabolic profile and vascular function in non-obese lean wistar rats [PDF]

open access: yes, 2012
A number of preclinical and clinical studies have reported blood-pressure-lowering benefits of thiazolidinediones in diabetic subjects and animal models of diabetes.
Abubakari, Abdul-Razak   +3 more
core   +1 more source

A PARTICLE FILTER BASED FRAMEWORK FOR THE PROGNOSIS OF ATHEROSCLEROSIS VIA LUMPED CARDIOVASCULAR MODELING

open access: yesInternational Journal of Prognostics and Health Management, 2019
Atherosclerosis refers to the plaque deposition in the arteries that can eventually lead to any of the three cardiovascular diseases, namely, heart attack, stroke, or peripheral vascular disease, depending upon the site of the blockage in the human ...
Karan Jain, Arijit Guha, Amit Patra
doaj   +1 more source

Primary Role of the Kidney in Pathogenesis of Hypertension

open access: yesLife
Previous transplantation studies and the concept of ‘nephron underdosing’ support the idea that the kidney plays a crucial role in the development of essential hypertension.
Gheun-Ho Kim
doaj   +1 more source

Maternal Cardiovascular Impairment in Pregnancies Complicated by Severe Fetal Growth Restriction [PDF]

open access: yes, 2012
—Fetal growth restriction and preeclampsia are both conditions of placental etiology and associated to increased risk for the long-term development of cardiovascular disease in the mother. At presentation, preeclampsia is associated with maternal global
Liberati, M   +3 more
core   +1 more source

Angiotensin receptor blockade with Losartan attenuates pressor response to handgrip contraction and enhances natriuresis in salt loaded hypertensive subjects: a quasi-experimental study among Nigerian adults

open access: yesThe Pan African Medical Journal, 2019
INTRODUCTION: Sympathetic and Renin-Angiotensin-Aldosterone systems play crucial roles in blood pressure response to increased salt intake. This study investigated the effects of angiotensin receptor blocker (ARB) and sympathetic excitation on the ...
Francis Muyiwa Agbaraolorunpo   +3 more
doaj   +1 more source

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