Vascular stiffness in insulin resistance and obesity [PDF]
Obesity, insulin resistance, and type 2 diabetes are associated with a substantially increased prevalence of vascular fibrosis and stiffness, with attendant increased risk of cardiovascular and chronic kidney disease. Although the underlying mechanisms and mediators of vascular stiffness are not well understood, accumulating evidence supports the role ...
Guanghong Jia +2 more
exaly +4 more sources
Calculating vascular resistances [PDF]
AbstractVascular resistance calculations often affect decisions regarding therapeutic options encountered by physicians and their patients. However, many of the terms, units, and methods used when calculating vascular resistances are ambiguous. This report attempts to clarify some of these ambiguities and suggests methods for predicting normal vascular
J W, Skimming, S, Cassin, W W, Nichols
openaire +2 more sources
Impaired decidual natural killer cell regulation of vascular remodelling in early human pregnancies with high uterine artery resistance [PDF]
During human pregnancy, natural killer (NK) cells accumulate in the maternal decidua, but their specific roles remain to be determined. Decidual NK (dNK) cells are present during trophoblast invasion and uterine spiral artery remodelling.
Cartwright, JE +6 more
core +1 more source
Absence of reflex vascular responses from the intrapulmonary circulation in anaesthetised dogs [PDF]
The aim of this investigation was to determine whether reflex cardiovascular responses were obtained to localised distension of the intrapulmonary arterial and venous circulations in a preparation in which the stimuli to other major reflexogenic areas ...
Drinkhill, M.J. +3 more
core +1 more source
Vascular smooth muscle contraction in hypertension [PDF]
Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia and chronic kidney disease.
Alves-Lopes, Rheure +6 more
core +1 more source
Mitigation of Radiation Induced Pulmonary Vascular Injury by Delayed Treatment with Captopril [PDF]
Background and Objective: A single dose of 10 Gy radiation to the thorax of rats results in decreased total lung angiotensin-converting enzyme (ACE) activity, pulmonary artery distensibility and distal vascular density while increasing pulmonary ...
Fish, Brian L. +5 more
core +2 more sources
Maternal haemodynamic function differs in pre‐eclampsia when it is associated with a small‐for‐gestational‐age newborn: a prospective cohort study [PDF]
Objective To describe maternal haemodynamic differences in gestational hypertension with small‐for‐gestational‐age babies (HDP + SGA), gestational hypertension with appropriate‐for‐gestational‐age babies (HDP‐only) and control pregnancies.
Binder, J +4 more
core +1 more source
Microvascular alterations in hypertension and vascular aging [PDF]
Hypertension and aging are characterized by vascular remodelling and stiffness as well as endothelial dysfunction. Endothelial function declines with age, since aging is associated with senescence of the endothelium due to increased rate of apoptosis and
Battistoni, Allegra +5 more
core +1 more source
Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. [PDF]
BACKGROUND: Riociguat, a member of a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension. METHODS: In this phase 3,
CHEST-1 Study Group, +13 more
core +1 more source
METOCLOPRAMIDE AND RENAL VASCULAR RESISTANCE
We have studied the effect of i.v. metoclopramide on renal vascular resistance in nine healthy volunteers. Peak systolic and end-diastolic frequencies were measured using duplex Doppler ultrasound of a renal interlobar artery, before and after the administration of i.v. metoclopramide 10 mg, and the resistance index derived.
A R, Manara +4 more
openaire +2 more sources

